Development Level

Tbio 9 | 11,445
Tchem 8 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

decreased bone mineral density 3 | 126
decreased grip strength 2 | 116
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal limb position 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating iron lev... 1 | 32
decreased heart rate 1 | 18
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
increased total body fat amoun... 1 | 134
prolonged RR interval 1 | 8
thin skin 1 | 2
trunk curl 1 | 16

Disease

Carcinoma 16 | 11,493
ovarian cancer 16 | 8,520
osteosarcoma 10 | 7,950
glioblastoma 9 | 5,792
subependymal giant cell astrocytoma 8 | 2,287
atypical teratoid / rhabdoid tumor 7 | 5,112
malignant mesothelioma 7 | 3,232
medulloblastoma, large-cell 7 | 6,241
non-small cell lung cancer 7 | 2,890
psoriasis 7 | 6,694
Autosomal recessive predisposition 6 | 1,442
Astrocytoma, Pilocytic 5 | 3,081
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
invasive ductal carcinoma 5 | 2,951
Cancer 4 | 2,499
Kidney cancer 4 | 2,613
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
primary pancreatic ductal adenocarcinoma 4 | 1,109
Acquired scoliosis 3 | 281
Breast cancer 3 | 3,578
Cataract 3 | 297
Congenital clubfoot 3 | 109
Curvature of spine 3 | 282
Lens Opacities 3 | 231
Multiple myeloma 3 | 1,332
Myopia 3 | 176
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Abnormality of metabolism/homeostasis 2 | 134
Atopic dermatitis 2 | 952
Blepharoptosis 2 | 231
Bruck syndrome 2 | 10
Cervical incompetence 2 | 6
Congestive heart failure 2 | 113
Crohn's disease 2 | 321
Degenerative polyarthritis 2 | 115
Ecchymosis 2 | 66
Ehlers-Danlos syndrome 2 | 43
Flexion contracture - elbow 2 | 32
Generalized osteopenia 2 | 99
Heart failure 2 | 162
Hernia, Inguinal 2 | 89
Hyperkyphosis 2 | 111
Increased tendency to bruise 2 | 66
Kyphosis deformity of spine 2 | 114
Low Vision 2 | 174
Muscle hypotonia 2 | 571
Nail dysplasia 2 | 52
Osteoarthritis 2 | 184
Osteogenesis imperfecta 2 | 34
Osteopenia 2 | 99
Osteoporosis 2 | 363
Pick disease 2 | 1,894
Platyspondyly 2 | 56
Polycythemia 2 | 25
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Retinal Diseases 2 | 55
Seizures 2 | 596
Visual Impairment 2 | 174
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
Acquired flat foot 1 | 72
Acute cystitis 1 | 35
CD40 deficiency 1 | 4
Cellulitis 1 | 20
Cystinuria 1 | 18
Gastroenteritis 1 | 41
Hematocrit increased 1 | 5
Hemiplegia and hemiparesis 1 | 38
Hemoglobin increased 1 | 6
Increased red blood cell mass 1 | 4
Joint laxity 1 | 54
Menkes disease 1 | 19
Osteogenesis imperfecta type III (disorder) 1 | 11
Persistent generalized lymphadenopathy 1 | 15
Pheochromocytoma 1 | 24
Pleural empyema 1 | 12
Shallow orbits 1 | 13
Ullrich congenital muscular dystrophy 1 | 5
osteogenesis imperfecta type 3 1 | 11

Tissue

Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Enzyme 17 | 4,145
Non-IDG 3 | 12,091

UniProt Keyword

Vitamin C 20 | 20
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane prolyl 4-hydroxylase P4HTM Tchem Enzyme -2.70235 473.8 159
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 OGFOD2 Tdark Enzyme 0.00000 86
Prolyl 3-hydroxylase 2 P3H2 Tbio Enzyme -2.49306 295.2 60
Peptidyl-glycine alpha-amidating monooxygenase PAM Tchem Enzyme -2.61669 398.2 81
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 PLOD2 Tbio Enzyme -2.34578 220.4 127
Egl nine homolog 2 EGLN2 Tchem Non-IDG -2.03430 0.00000 318
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 PLOD1 Tbio Enzyme -2.10120 119.8 88
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 ALKBH3 Tchem Enzyme -1.51372 33.2 194
Prolyl 3-hydroxylase 3 P3H3 Tbio Enzyme -1.97511 85.0 71
Prolyl 4-hydroxylase subunit alpha-2 P4HA2 Tbio Enzyme -1.04006 10.9 76