Development Level

Tbio 5 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
decreased fasted circulating g... 1 | 65
decreased large unstained cell... 1 | 11
decreased neutrophil cell numb... 1 | 42
impaired righting response 1 | 26
increased circulating total pr... 1 | 28
increased lymphocyte cell numb... 1 | 32
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Hypertension 5 | 396
Hypotension 5 | 82
Bradycardia 4 | 36
Breast cancer 4 | 3,578
Hypertensive disease 4 | 292
Arrhythmias, Cardiac 3 | 19
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Cardiac Arrhythmia 3 | 103
Cardiomyopathies 3 | 110
Cardiovascular Abnormalities 3 | 31
Cardiovascular Diseases 3 | 59
Cerebrovascular disease 3 | 238
Heart failure 3 | 162
Hyperalgesia 3 | 83
Kidney disease 3 | 430
Liver Cirrhosis 3 | 181
diabetes mellitus 3 | 1,728
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
ulcerative colitis 3 | 1,819
Acute kidney injury 2 | 70
Atherosclerosis 2 | 291
Bipolar Disorder 2 | 666
Carcinoma 2 | 11,493
Cardiomegaly 2 | 116
Coronary artery disease 2 | 268
Diabetes Mellitus, Experimental 2 | 108
Diabetic retinopathy 2 | 56
Diaphragmatic Hernia 2 | 40
Drug Overdose 2 | 2
Focal glomerulosclerosis 2 | 37
Glomerulosclerosis, Focal Segmental 2 | 28
Heart disease 2 | 306
Hernia, Diaphragmatic 2 | 40
Hyperaldosteronism 2 | 35
Hypertrophy 2 | 17
Hypertrophy, Left Ventricular 2 | 24
Hypokalemia 2 | 52
Inflammation 2 | 120
Kidney Diseases 2 | 114
Left Ventricular Hypertrophy 2 | 47
Liver Cirrhosis, Experimental 2 | 769
Lung disease 2 | 142
Major Depressive Disorder 2 | 301
Myocardial Ischemia 2 | 169
Myocardial Reperfusion Injury 2 | 37
Nephrosis 2 | 21
Obesity 2 | 678
Pain 2 | 103
Portal hypertension 2 | 20
Pre-Eclampsia 2 | 68
Pulmonary Fibrosis 2 | 106
Renal Insufficiency 2 | 90
Reperfusion Injury 2 | 86
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Unipolar Depression 2 | 250
Ureteral obstruction 2 | 33
Weight decreased 2 | 103
breast carcinoma 2 | 1,638
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
Acute Lung Injury 1 | 22
Albuminuria 1 | 21
Amnesia 1 | 17
Aneurysm, Dissecting 1 | 8
Anhedonia 1 | 27
Central Diabetes Insipidus 1 | 5
Cleft uvula 1 | 27
Craniopharyngioma 1 | 16
Diabetes insipidus 1 | 18
Erectile dysfunction 1 | 32
Gastrointestinal Hemorrhage 1 | 52
Heart Diseases 1 | 43
Hyponatremia 1 | 25
Hypopituitarism 1 | 40
Irritation - emotion 1 | 68
Langerhans-cell histiocytosis 1 | 12
Memory Disorders 1 | 40
Motion sickness 1 | 21
Mouth Abnormalities 1 | 14
Oral Ulcer 1 | 15
Peptic Ulcer 1 | 27
Peroneal nerve paralysis 1 | 11
Peroneal neuropathy 1 | 4
Polydipsia 1 | 15
Potter's facies 1 | 10
Premature canities 1 | 24
Respiratory Distress Syndrome, Adult 1 | 40
Retinopathy of prematurity 1 | 22
Septooptic dysplasia 1 | 19
Thin hypoplastic alae nasi 1 | 51
Thrombosis 1 | 46
Waardenburg's syndrome 1 | 17
blue iris (physical finding) 1 | 17

Tissue

Blood and immune system 5 | 16,909
Endocrine System 5 | 18,159
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Digestive Tract 4 | 17,369
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Respiratory system 4 | 16,393
Cardiovascular System 3 | 15,192
Nervous System 3 | 16,725

Target Family

Non-IDG 5 | 12,091

UniProt Keyword

Vasoconstrictor 5 | 5
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-3 EDN3 Tbio Non-IDG -2.96371 794.0 219
Endothelin-2 EDN2 Tbio Non-IDG -2.65568 390.3 131
Angiotensinogen AGT Tbio Non-IDG -3.24591 1711.3 695
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Vasopressin-neurophysin 2-copeptin AVP Tbio Non-IDG -3.92570 8381.2 203