Development Level

Tbio 141 | 10,625
Tchem 30 | 1,890
Tdark 4 | 7,003
Tclin 1 | 602

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 7 | 633
abnormal behavior 3 | 226
cataract 3 | 26
embryonic lethality prior to o... 3 | 148
embryonic lethality prior to t... 3 | 187
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 107
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
decreased body length 2 | 108
decreased circulating alanine ... 2 | 53
decreased circulating aspartat... 2 | 27
decreased lean body mass 2 | 195
decreased lumbar vertebrae num... 2 | 62
decreased total body fat amoun... 2 | 186
increased body weight 2 | 42
increased circulating alkaline... 2 | 119
increased sacral vertebrae num... 2 | 62
male infertility 2 | 62
thrombocytopenia 2 | 46
abnormal bone structure 1 | 131
abnormal coat/ hair morphology 1 | 18
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal limb bud morphology 1 | 15
abnormal liver size 1 | 4
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta size 1 | 10
abnormal posture 1 | 5
abnormal spinal cord morpholog... 1 | 8
abnormal stomach morphology 1 | 4
abnormal tail movements 1 | 12
abnormal vocalization 1 | 21
absent heartbeat 1 | 6
anophthalmia 1 | 20
decreased CD4-positive, alpha ... 1 | 19
decreased KLRG1-positive NK ce... 1 | 9
decreased KLRG1-positive T-hel... 1 | 2
decreased Ly6C high monocyte n... 1 | 18
decreased NK T cell number 1 | 28
decreased NK cell number 1 | 16
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased follicular B cell nu... 1 | 4
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased lactate dehydrogenas... 1 | 14
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
enlarged lymph nodes 1 | 27
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased CD8-positive, alpha-... 1 | 11
increased Ly6C low monocyte nu... 1 | 8
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased blood uric acid leve... 1 | 5
increased body length 1 | 20
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating fructosa... 1 | 11
increased circulating phosphat... 1 | 24
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased total body fat amoun... 1 | 57
pale liver 1 | 5
pale yolk sac 1 | 12
pallor 1 | 13
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
small testis 1 | 37
tremors 1 | 34

Disease

Cancer 113 | 2,346
ovarian cancer 105 | 8,484
osteosarcoma 90 | 7,933
medulloblastoma, large-cell 74 | 6,234
lung cancer 69 | 4,466
psoriasis 69 | 6,685
glioblastoma 64 | 5,572
malignant mesothelioma 55 | 3,162
Breast cancer 50 | 3,094
atypical teratoid / rhabdoid tumor 49 | 4,369
Carcinoma 47 | 2,147
invasive ductal carcinoma 42 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 41 | 2,956
non-small cell lung cancer 41 | 2,798
oligodendroglioma 41 | 2,849
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,289
lung adenocarcinoma 37 | 2,713
pancreatic cancer 37 | 2,300
primitive neuroectodermal tumor 37 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 36 | 2,988
ependymoma 34 | 2,514
group 3 medulloblastoma 32 | 2,254
pituitary cancer 32 | 1,972
ulcerative colitis 32 | 2,087
lung carcinoma 30 | 2,844
subependymal giant cell astrocytoma 30 | 2,287
astrocytic glioma 28 | 2,241
ductal carcinoma in situ 28 | 1,745
pediatric high grade glioma 28 | 2,712
adult high grade glioma 26 | 2,148
medulloblastoma 26 | 1,524
pilocytic astrocytoma 26 | 3,086
astrocytoma 24 | 1,493
Pick disease 23 | 1,893
adrenocortical carcinoma 23 | 1,427
atypical teratoid/rhabdoid tumor 23 | 1,095
Neoplastic Syndromes, Hereditary 22 | 48
acute quadriplegic myopathy 22 | 1,157
breast carcinoma 22 | 1,614
colon cancer 22 | 1,475
cystic fibrosis 22 | 1,665
group 4 medulloblastoma 22 | 1,875
Mammary Neoplasms 20 | 410
diabetes mellitus 20 | 1,663
interstitial cystitis 20 | 2,299
Stomach Neoplasms 18 | 282
juvenile dermatomyositis 18 | 1,189
spina bifida 18 | 1,064
tuberculosis 18 | 1,557
Adenoma 17 | 165
Lung Neoplasms 17 | 171
cutaneous lupus erythematosus 17 | 1,056
nasopharyngeal carcinoma 17 | 1,056
Prostatic Neoplasms 16 | 471
esophageal adenocarcinoma 16 | 737
gastric carcinoma 16 | 832
posterior fossa group A ependymoma 16 | 1,511
primary pancreatic ductal adenocarcinoma 16 | 1,271
sonic hedgehog group medulloblastoma 16 | 1,482
Intellectual disability 15 | 573
Multiple myeloma 15 | 1,327
Liver carcinoma 14 | 217
dermatomyositis 14 | 933
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
Colorectal Neoplasms 13 | 217
non-small cell lung carcinoma 13 | 413
posterior fossa group B ependymoma 13 | 1,530
Pancreatic Neoplasm 12 | 79
Renal Cell Carcinoma 12 | 199
Rheumatoid Arthritis 12 | 1,160
Autistic Disorder 11 | 320
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 499
pancreatic carcinoma 11 | 567
primary Sjogren syndrome 11 | 789
active Crohn's disease 10 | 918
aldosterone-producing adenoma 10 | 664
fibroadenoma 10 | 557
mucosa-associated lymphoid tissue lymphoma 10 | 480
ovarian neoplasm 10 | 97
progressive supranuclear palsy 10 | 674
Amyotrophic Lateral Sclerosis 9 | 431
Atopic dermatitis 9 | 944
Colon Carcinoma 9 | 25
Colonic Neoplasms 9 | 126
Down syndrome 9 | 548
Endometriosis 9 | 535
Familial adenomatous polyposis 9 | 31
Melanoma 9 | 261
Mesothelioma 9 | 40
Multiple Sclerosis 9 | 498
hepatocellular carcinoma 9 | 532
tuberculosis and treatment for 3 months 9 | 327
Adenocarcinoma 8 | 115
Glioma 8 | 65
Peripheral Neuropathy 8 | 303
Prostate cancer 8 | 172
active ulcerative colitis 8 | 477
acute myeloid leukemia 8 | 780
chronic rhinosinusitis 8 | 512
non primary Sjogren syndrome sicca 8 | 840

Tissue

Blood and immune system 174 | 17,995
Digestive Tract 174 | 18,473
Endocrine System 174 | 18,512
Female tissues 174 | 18,647
Liver and Pancreas 174 | 18,136
Male tissues 174 | 17,969
Nervous System 174 | 18,561
Urinary Tract 174 | 18,444
Cardiovascular System 173 | 17,958
Respiratory system 172 | 17,484
Skin and soft tissues 172 | 18,115

Target Family

Non-IDG 90 | 11,971
Enzyme 41 | 4,146
Kinase 17 | 634
Transcription Factor 16 | 1,400
Epigenetic 7 | 242
GPCR 3 | 406
TF/Epigenetic 1 | 38
Transporter 1 | 473

UniProt Keyword

Tumor suppressor 176 | 176
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Programmed cell death protein 4 PDCD4 Tchem Non-IDG -2.40380 284.9 546
N-acetyltransferase 6 NAT6 Tbio Enzyme -0.82623 6.53 132
5'-3' exoribonuclease 1 XRN1 Tbio Enzyme -2.06818 114.2 45
Merlin NF2 Tbio Non-IDG -3.13004 1456.9 431
Protein lin-9 homolog LIN9 Tbio Non-IDG -1.88736 79.3 89
Transmembrane protein 127 TMEM127 Tbio Non-IDG -1.21612 16.9 25
Cyclin-dependent kinase inhibitor 1C CDKN1C Tbio Enzyme -2.77104 600.5 488
PH domain leucine-rich repeat-containing protein phosphatase 2 PHLPP2 Tbio Enzyme -1.27425 16.1 120
Cell adhesion molecule 4 CADM4 Tbio Non-IDG -1.02667 13.5 184