Development Level

Tbio 22 | 11,445
Tchem 3 | 1,598
Tdark 3 | 6,588
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
abnormal behavior 1 | 298
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal skin morphology 1 | 50
decreased NK T cell number 1 | 2
decreased circulating serum al... 1 | 82
decreased lymphocyte cell numb... 1 | 83
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
limb grasping 1 | 41

Disease

Carcinoma 20 | 11,493
ovarian cancer 14 | 8,520
osteosarcoma 13 | 7,950
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
group 3 medulloblastoma 11 | 4,104
medulloblastoma, large-cell 11 | 6,241
Neurodegenerative disease 10 | 414
ependymoma 10 | 4,679
dentatorubral-pallidoluysian atrophy 9 | 21
psoriasis 9 | 6,694
Breast cancer 8 | 3,578
Deglutition Disorders 8 | 132
Dysarthria 8 | 192
Epilepsy 8 | 792
Kidney cancer 8 | 2,613
Schizophrenia 8 | 1,160
Huntington's disease 7 | 76
Intellectual disability 7 | 1,016
adult high grade glioma 7 | 3,801
lung cancer 7 | 4,740
Autosomal dominant cerebellar ataxia 6 | 33
Choreatic disease 6 | 52
astrocytic glioma 6 | 2,597
pituitary cancer 6 | 1,972
Astrocytoma, Pilocytic 5 | 3,081
Ataxia, Appendicular 5 | 25
Cerebellar Ataxia 5 | 304
Cerebellar Dysmetria 5 | 56
Dementia 5 | 175
Depressive disorder 5 | 409
Liver cancer 5 | 604
Machado-Joseph disease 5 | 18
Muscle hypotonia 5 | 571
Neuropathy 5 | 261
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic lateral sclerosis 4 | 451
Ataxia, Spinocerebellar 4 | 16
Atrophy of cerebellum 4 | 103
Babinski Reflex 4 | 100
Bradykinesia 4 | 34
Cancer 4 | 2,499
Cerebellar degeneration 4 | 103
Chorea 4 | 29
Decreased vibratory sense 4 | 7
Dystonia 4 | 164
Failure to gain weight 4 | 365
Gait Ataxia 4 | 51
Hypertension 4 | 396
Infratentorial atrophy 4 | 103
Kennedy's disease 4 | 11
Muscle Spasticity 4 | 195
Nystagmus, End-Position 4 | 12
Parkinson's disease 4 | 392
Pediatric failure to thrive 4 | 365
Progressive cerebellar ataxia 4 | 13
Progressive disorder 4 | 142
Rheumatoid arthritis 4 | 1,191
Seizures 4 | 596
Sphincter disturbances 4 | 16
Spinocerebellar Ataxias 4 | 34
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
Acquired scoliosis 3 | 281
Adult onset 3 | 82
Anxiety 3 | 136
Anxiety disease 3 | 113
Autism spectrum disorder 3 | 101
Autistic Disorder 3 | 364
Bipolar Disorder 3 | 666
Blepharoptosis 3 | 231
Curvature of spine 3 | 282
Decreased tendon reflex 3 | 122
Distal amyotrophy 3 | 51
Endometrial cancer 3 | 311
Gliosis 3 | 56
Melanoma 3 | 711
Mental Depression 3 | 333
Mood Disorders 3 | 184
Movement Disorders 3 | 55
Muscle Rigidity 3 | 49
PARKINSON DISEASE, LATE-ONSET 3 | 20
Sensory neuropathy 3 | 20
Skin cancer 3 | 469
Spinocerebellar ataxia type 1 3 | 16
Strabismus 3 | 270
X- linked recessive 3 | 110
lung carcinoma 3 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
tuberculosis 3 | 2,010

Tissue

Endocrine System 29 | 18,159
Skin and soft tissues 28 | 17,230
Male tissues 27 | 17,142
Digestive Tract 26 | 17,369
Female tissues 26 | 17,400
Nervous System 26 | 16,725
Blood and immune system 24 | 16,909
Urinary Tract 24 | 16,678
Cardiovascular System 23 | 15,192
Liver and Pancreas 23 | 16,750
Respiratory system 23 | 16,393

Target Family

Non-IDG 15 | 12,091
Transcription Factor 9 | 1,400
Ion Channel 2 | 344
Enzyme 1 | 4,145
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

Triplet repeat expansion 30 | 30
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Androgen receptor AR Tclin Nuclear Receptor -3.82874 7137.7 1609
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
TATA-box-binding protein TBP Tbio Non-IDG -3.27246 1844.4 387
Zinc finger protein ZIC 3 ZIC3 Tbio Transcription Factor -3.08151 1223.6 173
Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A Tchem Ion Channel -3.06226 1140.1 64
Frataxin, mitochondrial FXN Tbio Non-IDG -3.02739 1114.8 403
Ataxin-3 ATXN3 Tbio Non-IDG -2.89207 773.7 230
Forkhead box protein L2 FOXL2 Tbio Transcription Factor -2.81557 652.1 234
Neurogenic locus notch homolog protein 4 NOTCH4 Tchem Non-IDG -2.75010 557.0 225
Asporin ASPN Tbio Non-IDG -2.64447 408.2 128