Development Level

Tbio 67 | 11,651
Tdark 17 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 13 | 979
embryonic lethality prior to o... 3 | 239
abnormal behavior 2 | 298
decreased bone mineral content 2 | 151
embryonic lethality prior to t... 2 | 278
increased or absent threshold ... 2 | 101
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal radius morphology 1 | 8
abnormal scapula morphology 1 | 3
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal ulna morphology 1 | 8
absent pinna reflex 1 | 23
brachydactyly 1 | 19
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating lipase l... 1 | 3
decreased circulating serum al... 1 | 82
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hyperactivity 1 | 148
increased circulating alkaline... 1 | 122
increased circulating glucose ... 1 | 24
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
kyphosis 1 | 5
prenatal lethality prior to he... 1 | 87
syndactyly 1 | 23

Disease

ovarian cancer 53 | 8,520
Carcinoma 49 | 11,493
osteosarcoma 41 | 7,950
lung cancer 36 | 4,740
medulloblastoma, large-cell 31 | 6,241
group 3 medulloblastoma 29 | 4,104
atypical teratoid / rhabdoid tumor 26 | 5,112
glioblastoma 24 | 5,792
ependymoma 22 | 4,679
psoriasis 22 | 6,694
Breast cancer 20 | 3,578
malignant mesothelioma 17 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
adult high grade glioma 16 | 3,801
astrocytic glioma 16 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
primitive neuroectodermal tumor 14 | 3,035
Kidney cancer 13 | 2,613
dermatomyositis 13 | 966
non-small cell lung cancer 13 | 2,890
oligodendroglioma 13 | 2,850
Astrocytoma, Pilocytic 12 | 3,081
invasive ductal carcinoma 12 | 2,951
subependymal giant cell astrocytoma 12 | 2,287
Multiple myeloma 11 | 1,332
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
Pick disease 10 | 1,894
acute quadriplegic myopathy 9 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Cancer 8 | 2,499
Deafness dystonia syndrome 7 | 21
Dystonia 7 | 164
Waldenstrons macroglobulinemia 7 | 765
group 4 medulloblastoma 7 | 1,855
lung carcinoma 7 | 2,843
tuberculosis 7 | 2,010
Autosomal recessive predisposition 6 | 1,442
acute myeloid leukemia 6 | 783
breast carcinoma 6 | 1,638
diabetes mellitus 6 | 1,728
juvenile dermatomyositis 6 | 1,187
pediatric high grade glioma 6 | 1,064
colon cancer 5 | 1,478
non primary Sjogren syndrome sicca 5 | 891
pancreatic cancer 5 | 2,398
Optic Atrophy 4 | 242
Rheumatoid arthritis 4 | 1,191
Short stature 4 | 531
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,312
interstitial lung disease 4 | 298
ulcerative colitis 4 | 1,819
Amyotrophic lateral sclerosis 3 | 451
Atopic dermatitis 3 | 952
Barth syndrome 3 | 23
Cerebellar Ataxia 3 | 304
Cognitive delay 3 | 608
Gaucher disease type 1 3 | 180
Global developmental delay 3 | 608
Hyperreflexia 3 | 209
Liver Cirrhosis, Experimental 3 | 769
Low Vision 3 | 174
Mental and motor retardation 3 | 608
Muscle Spasticity 3 | 195
Visual Impairment 3 | 174
cutaneous lupus erythematosus 3 | 1,057
hepatocellular carcinoma 3 | 547
lung adenocarcinoma 3 | 2,716
nasopharyngeal carcinoma 3 | 1,058
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074
3-methylglutaconic aciduria 2 | 29
Alzheimer's disease 2 | 658
Anteverted nostril 2 | 191
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Duchenne muscular dystrophy 2 | 601
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Kidney Failure 2 | 111
Leukemia 2 | 104
Melanoma 2 | 711
Multiple Sclerosis 2 | 540
Pediatric failure to thrive 2 | 365
Prostatic Neoplasms 2 | 495
Seizures 2 | 596
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
glioblastoma multiforme 2 | 142
medulloblastoma 2 | 720
pancreatic carcinoma 2 | 562
pulmonary arterial hypertension 2 | 76
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Blood and immune system 83 | 16,909
Cardiovascular System 83 | 15,192
Digestive Tract 83 | 17,369
Endocrine System 83 | 18,159
Female tissues 83 | 17,400
Liver and Pancreas 83 | 16,750
Male tissues 83 | 17,142
Nervous System 83 | 16,725
Skin and soft tissues 83 | 17,230
Urinary Tract 83 | 16,678
Respiratory system 82 | 16,393

Target Family

Non-IDG 62 | 12,091
Enzyme 23 | 4,145

UniProt Keyword

Translocation 85 | 85
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear pore complex protein Nup50 NUP50 Tbio Non-IDG -1.18445 15.9 270
Mitochondrial import inner membrane translocase subunit Tim10 B TIMM10B Tdark Enzyme 0.11 0.77 53
ATP-dependent RNA helicase DDX19A DDX19A Tdark Enzyme 0.02 0.99 63
ATP-dependent RNA helicase DDX19B DDX19B Tbio Enzyme -1.25103 10.1 252
Mitochondrial import inner membrane translocase subunit TIM44 TIMM44 Tdark Enzyme -1.53843 36.5 35
Mitochondrial import inner membrane translocase subunit Tim10 TIMM10 Tbio Enzyme -1.43229 27.7 55
Nucleoporin p58/p45 NUP58 Tdark Non-IDG -0.69756 4.39 42
Nuclear pore glycoprotein p62 NUP62 Tbio Non-IDG -1.80390 62.5 241
Nuclear pore complex protein Nup133 NUP133 Tbio Non-IDG -1.36479 22.8 72
Sentrin-specific protease 2 SENP2 Tbio Enzyme -0.25795 1.43 478