Development Level

Tbio 62 | 10,625
Tdark 19 | 7,003
Tchem 2 | 1,890

IMPC Term

preweaning lethality, complete... 9 | 633
abnormal behavior 2 | 226
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
embryonic lethality prior to o... 2 | 148
hyperactivity 2 | 108
abnormal bone structure 1 | 131
abnormal joint morphology 1 | 14
abnormal radius morphology 1 | 8
abnormal retinal outer nuclear... 1 | 5
abnormal scapula morphology 1 | 3
abnormal spine curvature 1 | 7
abnormal spleen morphology 1 | 36
abnormal ulna morphology 1 | 8
absent pinna reflex 1 | 21
decreased CD8-positive, alpha-... 1 | 26
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
increased circulating alkaline... 1 | 119
increased circulating glucose ... 1 | 16
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
kyphosis 1 | 5
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 51 | 8,484
osteosarcoma 40 | 7,933
lung cancer 36 | 4,466
medulloblastoma, large-cell 30 | 6,234
glioblastoma 24 | 5,572
atypical teratoid / rhabdoid tumor 23 | 4,369
group 3 medulloblastoma 23 | 2,254
psoriasis 22 | 6,685
Breast cancer 19 | 3,094
malignant mesothelioma 17 | 3,162
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,795
ependymoma 16 | 2,514
pediatric high grade glioma 16 | 2,712
Carcinoma 14 | 2,147
astrocytic glioma 14 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
primitive neuroectodermal tumor 14 | 3,031
non-small cell lung cancer 13 | 2,798
oligodendroglioma 13 | 2,849
dermatomyositis 12 | 933
invasive ductal carcinoma 12 | 2,950
pilocytic astrocytoma 12 | 3,086
subependymal giant cell astrocytoma 12 | 2,287
Multiple myeloma 11 | 1,327
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
Pick disease 10 | 1,893
acute quadriplegic myopathy 9 | 1,157
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
Cancer 8 | 2,346
Deafness dystonia syndrome 7 | 20
Waldenstrons macroglobulinemia 7 | 765
lung carcinoma 7 | 2,844
Dystonia 6 | 77
acute myeloid leukemia 6 | 780
adult high grade glioma 6 | 2,148
breast carcinoma 6 | 1,614
diabetes mellitus 6 | 1,663
group 4 medulloblastoma 6 | 1,875
juvenile dermatomyositis 6 | 1,189
medulloblastoma 6 | 1,524
astrocytoma 5 | 1,493
colon cancer 5 | 1,475
non primary Sjogren syndrome sicca 5 | 840
pancreatic cancer 5 | 2,300
posterior fossa group B ependymoma 5 | 1,530
sonic hedgehog group medulloblastoma 5 | 1,482
Rheumatoid Arthritis 4 | 1,160
adrenocortical carcinoma 4 | 1,427
cystic fibrosis 4 | 1,665
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,299
interstitial lung disease 4 | 291
posterior fossa group A ependymoma 4 | 1,511
ulcerative colitis 4 | 2,087
Atopic dermatitis 3 | 944
Barth syndrome 3 | 23
Gaucher disease type 1 3 | 171
atypical teratoid/rhabdoid tumor 3 | 1,095
cutaneous lupus erythematosus 3 | 1,056
hepatocellular carcinoma 3 | 532
lung adenocarcinoma 3 | 2,713
nasopharyngeal carcinoma 3 | 1,056
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 674
tuberculosis 3 | 1,557
tuberculosis and treatment for 3 months 3 | 327
tuberculosis and treatment for 6 months 3 | 686
3-methylglutaconic aciduria 2 | 29
Amyotrophic Lateral Sclerosis 2 | 431
Cortical blindness 2 | 15
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
HIV Infections 2 | 100
IGA Glomerulonephritis 2 | 454
Influenza 2 | 142
Kidney failure 2 | 39
Leukemia 2 | 88
Leukemia, Myelocytic, Acute 2 | 113
Melanoma 2 | 261
Multiple Sclerosis 2 | 498
Prostatic Neoplasms 2 | 471
Sensorineural hearing loss 2 | 107
Sleeping sickness 2 | 37
active ulcerative colitis 2 | 477
aldosterone-producing adenoma 2 | 664
gastric cancer 2 | 430
gastric carcinoma 2 | 832
glioblastoma multiforme 2 | 347
hereditary spastic paraplegia 2 | 313
pancreatic carcinoma 2 | 567
spina bifida 2 | 1,064
triple-A syndrome 2 | 18
Barrett's esophagus 1 | 183
Bejel 1 | 5
Brain disease 1 | 83
Cerebellar Ataxia 1 | 72
Cerebral amyloid angiopathy 1 | 9
Juvenile myoclonic epilepsy 1 | 17
Testicular Germ Cell Tumor 1 | 22
Yaws 1 | 8

Tissue

Blood and immune system 82 | 17,995
Cardiovascular System 82 | 17,958
Endocrine System 82 | 18,512
Female tissues 82 | 18,647
Liver and Pancreas 82 | 18,136
Male tissues 82 | 17,969
Nervous System 82 | 18,561
Digestive Tract 81 | 18,473
Respiratory system 81 | 17,484
Urinary Tract 81 | 18,444
Skin and soft tissues 80 | 18,115

Target Family

Non-IDG 60 | 11,971
Enzyme 23 | 4,146

UniProt Keyword

Translocation 83 | 83
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.21148 186.3 172
Protein ELYS AHCTF1 Tbio Non-IDG -1.30356 22.8 57
Nucleoporin p58/p45 NUP58 Tdark Non-IDG -0.70757 5.23 31
Nucleotide exchange factor SIL1 SIL1 Tbio Non-IDG -2.97229 967.7 187
Nucleoporin-like protein 2 NUPL2 Tbio Non-IDG -0.99049 10.1 66
Protein transport protein Sec61 subunit alpha isoform 1 SEC61A1 Tbio Non-IDG -2.43916 280.2 94
Protein transport protein Sec61 subunit gamma SEC61G Tdark Non-IDG -0.37727 2.21 27
Nuclear pore complex protein Nup85 NUP85 Tbio Non-IDG -1.18116 15.9 128
Mitochondrial import inner membrane translocase subunit Tim21 TIMM21 Tbio Enzyme -0.97772 10.6 24