Development Level

Tdark 474 | 6,593
Tbio 203 | 11,651
Tchem 114 | 1,388
Tclin 96 | 612

Collection

GPCR: IDG Consortium (Targets) 124 | 126
RFA-RM-18-021 100 | 328
GPCR: IDG Consortium (Complete... 25 | 25

IMPC Phenotype

decreased vertical activity 16 | 208
enlarged heart 12 | 210
preweaning lethality, complete... 12 | 979
abnormal behavior 11 | 298
preweaning lethality, incomple... 10 | 499
hyperactivity 9 | 148
abnormal heart morphology 8 | 162
increased lean body mass 8 | 172
decreased bone mineral content 7 | 151
decreased bone mineral density 7 | 126
decreased total body fat amoun... 7 | 207
abnormal bone structure 6 | 187
increased total body fat amoun... 6 | 134
decreased body weight 5 | 161
decreased lean body mass 5 | 135
decreased startle reflex 5 | 75
small superior vagus ganglion 5 | 74
abnormal gait 4 | 69
abnormal kidney morphology 4 | 65
abnormal seminal vesicle morph... 4 | 114
decreased hemoglobin content 4 | 68
decreased prepulse inhibition 4 | 82
improved glucose tolerance 4 | 79
increased circulating creatini... 4 | 38
increased circulating sodium l... 4 | 71
increased fasted circulating g... 4 | 76
increased heart weight 4 | 62
increased or absent threshold ... 4 | 101
increased startle reflex 4 | 112
abnormal behavioral response t... 3 | 66
abnormal epididymis morphology 3 | 42
abnormal skin coloration 3 | 25
abnormal skin morphology 3 | 50
decreased circulating insulin ... 3 | 76
decreased heart weight 3 | 27
decreased hematocrit 3 | 46
embryonic lethality prior to t... 3 | 278
female infertility 3 | 60
hypoactivity 3 | 132
impaired glucose tolerance 3 | 75
increased bone mineral content 3 | 108
increased circulating calcium ... 3 | 34
increased circulating triglyce... 3 | 42
increased erythrocyte cell num... 3 | 39
increased hemoglobin content 3 | 45
increased mean corpuscular vol... 3 | 92
male infertility 3 | 123
short tibia 3 | 97
abnormal eye morphology 2 | 68
abnormal liver morphology 2 | 17
abnormal sleep behavior 2 | 70
absent startle reflex 2 | 24
decreased circulating alanine ... 2 | 47
decreased circulating choleste... 2 | 93
decreased circulating iron lev... 2 | 32
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased eosinophil cell numb... 2 | 24
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
embryonic lethality prior to o... 2 | 239
enlarged epididymis 2 | 31
hydrometra 2 | 53
impaired pupillary reflex 2 | 26
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
microphthalmia 2 | 26
polycystic kidney 2 | 15
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small kidney 2 | 16
abnormal embryo turning 1 | 31
abnormal lymph node morphology 1 | 3
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
enlarged uterus 1 | 11
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating magnesiu... 1 | 10
limb grasping 1 | 41
prenatal lethality 1 | 28
scaly skin 1 | 4
small thymus 1 | 16
thick skin 1 | 4
vertebral fusion 1 | 23

Disease

Carcinoma 655 | 11,493
psoriasis 201 | 6,694
osteosarcoma 171 | 7,950
medulloblastoma, large-cell 158 | 6,241
ovarian cancer 147 | 8,520
glioblastoma 129 | 5,792
diabetes mellitus 125 | 1,728
lung cancer 120 | 4,740
atypical teratoid / rhabdoid tumor 117 | 5,112
ependymoma 117 | 4,679
adult high grade glioma 109 | 3,801
lung carcinoma 93 | 2,843
interstitial cystitis 87 | 2,312
Astrocytoma, Pilocytic 86 | 3,081
Schizophrenia 83 | 1,160
group 3 medulloblastoma 82 | 4,104
Kidney cancer 77 | 2,613
lung adenocarcinoma 77 | 2,716
Breast cancer 75 | 3,578
invasive ductal carcinoma 74 | 2,951
primitive neuroectodermal tumor 70 | 3,035
oligodendroglioma 68 | 2,850
malignant mesothelioma 66 | 3,232
non-small cell lung cancer 63 | 2,890
Cancer 60 | 2,499
astrocytic glioma 58 | 2,597
Bipolar Disorder 56 | 666
intraductal papillary-mucinous carcinoma (IPMC) 56 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 56 | 3,291
ulcerative colitis 56 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 53 | 2,955
pituitary cancer 51 | 1,972
tuberculosis 51 | 2,010
Obesity 50 | 678
ductal carcinoma in situ 50 | 1,745
subependymal giant cell astrocytoma 48 | 2,287
Depressive disorder 47 | 409
colon cancer 46 | 1,478
pancreatic cancer 46 | 2,398
breast carcinoma 45 | 1,638
Alcoholic Intoxication, Chronic 40 | 289
Asthma 36 | 385
Mood Disorders 36 | 184
group 4 medulloblastoma 36 | 1,855
Mental Depression 35 | 333
Major Depressive Disorder 34 | 301
cutaneous lupus erythematosus 34 | 1,057
adrenocortical carcinoma 32 | 1,428
cystic fibrosis 31 | 1,696
Melanoma 30 | 711
primary Sjogren syndrome 30 | 735
Epilepsy 29 | 792
Multiple Sclerosis 29 | 540
Pick disease 29 | 1,894
Parkinson's disease 28 | 392
Rheumatoid arthritis 28 | 1,191
astrocytoma 28 | 1,146
Autosomal recessive predisposition 25 | 1,442
Allergic rhinitis 24 | 95
Hypertension 24 | 396
Skin cancer 24 | 469
Unipolar Depression 24 | 250
Attention deficit hyperactivity disorder 22 | 278
Liver cancer 22 | 604
Common cold 21 | 69
Migraine 21 | 83
mucosa-associated lymphoid tissue lymphoma 21 | 484
Alcohol dependence 20 | 107
Nasal congestion 20 | 23
Atopic dermatitis 19 | 952
Autistic Disorder 19 | 364
Nasal discharge 19 | 25
Substance Withdrawal Syndrome 19 | 55
active Crohn's disease 19 | 922
Cocaine-Related Disorders 18 | 92
Pain 18 | 103
Pain agnosia 18 | 104
Seizures 18 | 596
pediatric high grade glioma 18 | 1,064
primary pancreatic ductal adenocarcinoma 18 | 1,109
Liver Cirrhosis, Experimental 17 | 769
esophageal adenocarcinoma 17 | 737
gastric carcinoma 17 | 807
medulloblastoma 17 | 720
active ulcerative colitis 16 | 764
non primary Sjogren syndrome sicca 16 | 891
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Acquired metabolic disease 15 | 336
Alzheimer's disease 15 | 658
Status Epilepticus 15 | 98
fibroadenoma 15 | 559
hepatocellular carcinoma 15 | 547
Endometriosis 14 | 540
Hypertensive disease 14 | 292
Hypotension 14 | 82
Intellectual disability 14 | 1,016
Vascular disease 14 | 319
acute myeloid leukemia 14 | 783
juvenile dermatomyositis 14 | 1,187
pancreatic carcinoma 14 | 562

Tissue

Endocrine System 518 | 18,159
Female tissues 426 | 17,400
Digestive Tract 405 | 17,369
Nervous System 401 | 16,725
Male tissues 399 | 17,142
Blood and immune system 392 | 16,909
Skin and soft tissues 392 | 17,230
Urinary Tract 361 | 16,678
Liver and Pancreas 359 | 16,750
Respiratory system 344 | 16,393
Cardiovascular System 299 | 15,192

Target Family

oGPCR 421 | 421
GPCR 405 | 408
Non-IDG 46 | 12,091
Enzyme 15 | 4,145

UniProt Keyword

Transducer 887 | 887
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Olfactory receptor 5H15 OR5H15 Tdark oGPCR 0.00000 35
Olfactory receptor 7D2 OR7D2 Tdark oGPCR 0.00000 2
Leukotriene B4 receptor 1 LTB4R Tchem GPCR -2.74171 557.6 365
Long-wave-sensitive opsin 1 OPN1LW Tbio GPCR -2.37983 238.7 47
Medium-wave-sensitive opsin 1 OPN1MW Tbio GPCR -0.97721 8.41 18
Olfactory receptor 5B21 OR5B21 Tdark oGPCR 0.00000 4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
Mas-related G-protein coupled receptor member X1 MRGPRX1 Tchem GPCR -1.21830 18.4 75
G-protein coupled receptor 176 GPR176 Tbio GPCR -2.38327 235.4 133
Opsin-5 OPN5 Tbio GPCR -1.19753 14.2 151