Development Level

Tbio 1 | 11,445
Tclin 1 | 613

Disease

Cancer 2 | 2,499
Constipation 2 | 181
Dyschezia 2 | 135
Hyperthyroidism 2 | 53
Hypothyroidism 2 | 122
Thyrotoxicosis 2 | 38
diabetes mellitus 2 | 1,728
psoriasis 2 | 6,694
AMYLOIDOSIS, HEREDITARY, TRANSTHYRETIN-RELATED 1 | 1
Abdomen distended 1 | 43
Addison's disease 1 | 31
Adult onset 1 | 82
Amyloid Neuropathies, Familial 1 | 1
Amyloid deposition in the vitreous humor 1 | 1
Amyloidosis 1 | 67
Amyloidosis, Familial 1 | 3
Autoimmune Diseases 1 | 67
Autoimmune thyroiditis 1 | 27
Autonomic nervous system disorders 1 | 19
Autonomic neuropathy 1 | 22
Axonal neuropathy 1 | 27
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Carotenemia 1 | 3
Celiac disease 1 | 116
Cerebrospinal fluid protein increased above normal 1 | 14
Chemical and Drug Induced Liver Injury 1 | 195
Choroid Plexus Papilloma 1 | 10
Coarse facial features 1 | 108
Compensated hypothyroidism 1 | 5
Congenital deafness 1 | 185
Congenital hypothyroidism 1 | 26
Constrictive median neuropathy 1 | 2
Deafness 1 | 198
Decreased tendon reflex 1 | 122
Decubitus ulcer 1 | 13
Dementia 1 | 175
Diarrhea 1 | 253
Digital flexor tenosynovitis 1 | 1
Drug Eruptions 1 | 18
Dwarfism 1 | 37
Dysarthria 1 | 192
Dysautonomia 1 | 20
Dystransthyretinemic Euthyroidal Hyperthyroxinemia 1 | 1
Endocrine exophthalmos 1 | 1
Erectile dysfunction 1 | 32
Exophthalmos 1 | 112
Fatigue 1 | 182
Goiter 1 | 38
Graves' disease 1 | 24
Headache 1 | 37
Hearing Loss, Partial 1 | 185
Hemiparesis 1 | 34
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hypersomnia 1 | 8
Hyperthyroxinemia 1 | 9
Hypervitaminosis A 1 | 13
Hypoparathyroidism 1 | 41
Icterus 1 | 82
Large bregma sutures 1 | 46
Large fontanelle 1 | 46
Large, late-closing fontanelle 1 | 46
Lattice corneal dystrophy 1 | 8
Liver cancer 1 | 604
Liver disease 1 | 237
Low Vision 1 | 174
Lupus erythematosus 1 | 57
Macroglossia 1 | 65
Muscle Spasticity 1 | 195
Muscle Weakness 1 | 170
Neuropathy 1 | 261
Orthostatic hypotension due to autonomic dysfunction 1 | 5
Parathyroid Adenoma 1 | 19
Pendred Syndrome 1 | 22
Peripheral Neuropathy 1 | 134
Peripheral axonal neuropathy 1 | 18
Phenotypic variability 1 | 150
Pneumonia 1 | 174
Polyneuropathy 1 | 64
Polyneuropathy in other endocrine and metabolic diseases 1 | 1
Progressive disorder 1 | 142
Stroke-like episodes 1 | 10
Thickened facial skin with coarse facial features 1 | 108
Thyroid Dyshormonogenesis 3 1 | 1
Thyroid adenoma 1 | 10
Thyroid carcinoma 1 | 5
Thyroiditis 1 | 29
Thyroiditis, Autoimmune 1 | 4
Transthyretin amyloidosis 1 | 1
Transthyretin related familial amyloid cardiomyopathy 1 | 1
Tremor 1 | 113
Urinary Incontinence 1 | 50
Visual Impairment 1 | 174
Vitamin B 6 Deficiency 1 | 1
Vitiligo 1 | 73
Wide bregma sutures 1 | 46
hearing impairment 1 | 199
protein-energy malnutrition 1 | 8

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Non-IDG 2 | 12,091

UniProt Keyword

Thyroid hormone 2 | 2
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyroglobulin TG Tbio Non-IDG -3.88676 7423.9 1081
Transthyretin TTR Tclin Non-IDG -3.79596 6198.3 750