Development Level

Tbio 17 | 11,445

IMPC Phenotype

abnormal bone structure 2 | 187
abnormal behavioral response t... 1 | 66
abnormal heart morphology 1 | 162
abnormal motor learning 1 | 3
abnormal response to new envir... 1 | 10
abnormal sleep behavior 1 | 70
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
convulsive seizures 1 | 13
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased urine creatinine lev... 1 | 3
increased body length 1 | 32
increased circulating chloride... 1 | 41
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134

Disease

Carcinoma 17 | 11,493
Kidney cancer 12 | 2,613
acute quadriplegic myopathy 10 | 1,158
psoriasis 10 | 6,694
Melanoma 9 | 711
Skin cancer 9 | 469
Distal arthrogryposis 8 | 42
Breast cancer 6 | 3,578
Hypertrophic Cardiomyopathy 5 | 117
Autosomal recessive predisposition 4 | 1,442
Dilated cardiomyopathy 4 | 56
Duchenne muscular dystrophy 4 | 601
Endometrial cancer 4 | 311
Liver cancer 4 | 604
Myopathy 4 | 185
Ophthalmoplegia 4 | 106
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
lung adenocarcinoma 4 | 2,716
medulloblastoma, large-cell 4 | 6,241
Arthrogryposis 3 | 54
Becker muscular dystrophy 3 | 191
Blepharoptosis 3 | 231
Byzanthine arch palate 3 | 194
Cardiomyopathy 3 | 116
Cardiomyopathy, Dilated 3 | 83
Cardiomyopathy, Familial Hypertrophic, 1 3 | 6
Cardiomyopathy, Hypertrophic, Familial 3 | 9
Congestive heart failure 3 | 113
Distal arthrogryposis syndrome 3 | 8
Familial isolated dilated cardiomyopathy 3 | 41
LEFT VENTRICULAR NONCOMPACTION 10 3 | 40
LEFT VENTRICULAR NONCOMPACTION 8 3 | 40
Left ventricular noncompaction 3 | 26
MYH-9 related disease 3 | 12
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
limb girdle muscular dystrophy 2A 3 | 213
osteosarcoma 3 | 7,950
primitive neuroectodermal tumor 3 | 3,035
Abnormality of metabolism/homeostasis 2 | 134
Acquired scoliosis 2 | 281
Adducted thumb 2 | 22
Amyotrophic lateral sclerosis 2 | 451
Ankyloglossia 2 | 17
Astrocytoma, Pilocytic 2 | 3,081
Asymmetric Septal Hypertrophy 2 | 7
Atrial Septal Defects 2 | 85
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cardiomegaly 2 | 116
Cardiomyopathy, Familial Hypertrophic, 1 (disorder) 2 | 7
Cardiomyopathy, Hypertrophic 2 | 24
Chest Pain 2 | 38
Clubfoot 2 | 39
Conduction disorder of the heart 2 | 79
Congenital clubfoot 2 | 109
Curvature of spine 2 | 282
Deglutition Disorders 2 | 132
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Failure to gain weight 2 | 365
Flexion contracture of proximal interphalangeal joint 2 | 75
Generalized muscle weakness 2 | 57
Heart failure 2 | 162
Highly variable severity 2 | 157
Hypoplastic mandible condyle 2 | 275
Joint stiffness 2 | 84
Kidney disease 2 | 430
Metatarsus Varus 2 | 24
Myocardial Infarction 2 | 151
Narrow face 2 | 54
Neck muscle weakness 2 | 17
Overlapping fingers 2 | 10
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Primary cutaneous amyloidosis 2 | 29
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Subaortic stenosis 2 | 9
Talipes foot deformities 2 | 20
Thin face 2 | 54
Toeing-in 2 | 24
Ulnar deviation of the fingers 2 | 21
Variable expressivity 2 | 157
adult high grade glioma 2 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
pediatric high grade glioma 2 | 1,064
posterior fossa group B ependymoma 2 | 416

Tissue

Endocrine System 17 | 18,159
Skin and soft tissues 17 | 17,230
Digestive Tract 16 | 17,369
Male tissues 15 | 17,142
Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Nervous System 12 | 16,725
Urinary Tract 12 | 16,678
Respiratory system 11 | 16,393

Target Family

Non-IDG 17 | 12,091

UniProt Keyword

Thick filament 17 | 17
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
Myosin-15 MYH15 Tbio Non-IDG -0.95780 9.01 40
Myosin-8 MYH8 Tbio Non-IDG -1.71003 48.7 39
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Myosin-3 MYH3 Tbio Non-IDG -1.74714 48.2 51
Myosin-7 MYH7 Tbio Non-IDG -2.64013 417.6 176
Myosin-1 MYH1 Tbio Non-IDG -1.94251 72.6 122