Development Level

Tbio 97 | 11,651
Tdark 62 | 6,593
Tchem 6 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 6 | 499
decreased body length 4 | 101
decreased circulating glucose ... 4 | 126
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
abnormal bone structure 3 | 187
cataract 3 | 92
decreased bone mineral content 3 | 151
decreased total body fat amoun... 3 | 207
increased lean body mass 3 | 172
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal lens morphology 2 | 81
absent pinna reflex 2 | 23
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 38
decreased circulating triglyce... 2 | 79
decreased heart rate 2 | 18
decreased mean corpuscular hem... 2 | 50
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
vertebral fusion 2 | 23
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal hair growth 1 | 10
abnormal heart morphology 1 | 162
abnormal limb position 1 | 3
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal vertebrae morphology 1 | 18
abnormal zygomatic bone morpho... 1 | 3
absent startle reflex 1 | 24
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
long tibia 1 | 25
male infertility 1 | 123
prolonged RR interval 1 | 8
small adrenal glands 1 | 16
thin skin 1 | 2
thrombocytosis 1 | 27
vertebral transformation 1 | 12

Disease

Carcinoma 127 | 11,493
ovarian cancer 87 | 8,520
osteosarcoma 76 | 7,950
ependymoma 58 | 4,679
medulloblastoma, large-cell 58 | 6,241
glioblastoma 57 | 5,792
psoriasis 56 | 6,694
atypical teratoid / rhabdoid tumor 55 | 5,112
group 3 medulloblastoma 42 | 4,104
lung cancer 37 | 4,740
Kidney cancer 35 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
adult high grade glioma 33 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
astrocytic glioma 32 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,955
Breast cancer 30 | 3,578
invasive ductal carcinoma 26 | 2,951
malignant mesothelioma 26 | 3,232
oligodendroglioma 26 | 2,850
Pick disease 25 | 1,894
Astrocytoma, Pilocytic 24 | 3,081
lung adenocarcinoma 23 | 2,716
lung carcinoma 22 | 2,843
Rheumatoid arthritis 21 | 1,191
primitive neuroectodermal tumor 21 | 3,035
subependymal giant cell astrocytoma 20 | 2,287
Autosomal recessive predisposition 18 | 1,442
pancreatic cancer 18 | 2,398
interstitial cystitis 17 | 2,312
juvenile dermatomyositis 17 | 1,187
non-small cell lung cancer 17 | 2,890
progressive supranuclear palsy 17 | 676
Cancer 16 | 2,499
acute quadriplegic myopathy 16 | 1,158
chronic rhinosinusitis 16 | 512
nasopharyngeal carcinoma 16 | 1,058
breast carcinoma 14 | 1,638
cystic fibrosis 14 | 1,696
diabetes mellitus 14 | 1,728
tuberculosis 14 | 2,010
non primary Sjogren syndrome sicca 13 | 891
spina bifida 13 | 1,074
Multiple myeloma 12 | 1,332
adrenocortical carcinoma 12 | 1,428
dermatomyositis 12 | 966
ductal carcinoma in situ 12 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
ulcerative colitis 12 | 1,819
Intellectual disability 11 | 1,016
Waldenstrons macroglobulinemia 11 | 765
Neurodegenerative disease 10 | 414
astrocytoma 10 | 1,146
group 4 medulloblastoma 10 | 1,855
Liver cancer 9 | 604
Obesity 9 | 678
Short stature 9 | 531
active Crohn's disease 9 | 922
medulloblastoma 9 | 720
pediatric high grade glioma 9 | 1,064
pituitary cancer 9 | 1,972
Alzheimer's disease 8 | 658
Ciliopathy 8 | 71
Endometrial cancer 8 | 311
Retinitis Pigmentosa 8 | 226
colon cancer 8 | 1,478
cutaneous lupus erythematosus 8 | 1,057
gastric cancer 8 | 459
primary Sjogren syndrome 8 | 735
primary pancreatic ductal adenocarcinoma 8 | 1,109
Duchenne muscular dystrophy 7 | 601
Polydactyly 7 | 107
acute myeloid leukemia 7 | 783
Atopic dermatitis 6 | 952
Bardet-Biedl syndrome 6 | 51
Cataract 6 | 297
Dull intelligence 6 | 645
Endometriosis 6 | 540
Epilepsy 6 | 792
Hepatomegaly 6 | 285
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Muscle hypotonia 6 | 571
Nephronophthisis 6 | 80
Neuropathy 6 | 261
Nystagmus 6 | 317
Poor school performance 6 | 645
aldosterone-producing adenoma 6 | 665
Cerebellar Ataxia 5 | 304
Cognitive delay 5 | 608
Depressive disorder 5 | 409
Down syndrome 5 | 499
Global developmental delay 5 | 608
Hydrocephalus 5 | 152
Hypertensive disease 5 | 292
Lens Opacities 5 | 231
Mental and motor retardation 5 | 608
Schizophrenia 5 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510

Tissue

Endocrine System 162 | 18,159
Blood and immune system 159 | 16,909
Digestive Tract 159 | 17,369
Female tissues 159 | 17,400
Male tissues 159 | 17,142
Respiratory system 159 | 16,393
Skin and soft tissues 158 | 17,230
Liver and Pancreas 156 | 16,750
Nervous System 156 | 16,725
Urinary Tract 154 | 16,678
Cardiovascular System 147 | 15,192

Target Family

Non-IDG 131 | 12,091
Enzyme 31 | 4,145
Epigenetic 2 | 242
Kinase 2 | 634

UniProt Keyword

TPR repeat 166 | 166
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
RanBP2-like and GRIP domain-containing protein 3 RGPD3 Tdark Non-IDG 0.00000 0
Protein TANC1 TANC1 Tdark Non-IDG -1.18264 15.5 31
Tetratricopeptide repeat protein 33 TTC33 Tdark Non-IDG -0.17609 1.75 123
Tetratricopeptide repeat protein 38 TTC38 Tdark Non-IDG 0.51 0.11 25
Calcineurin-binding protein cabin-1 CABIN1 Tbio Non-IDG -3.37173 2194.3 57
General transcription factor 3C polypeptide 3 GTF3C3 Tdark Non-IDG 0.10 0.58 197
Dynein assembly factor 4, axonemal DNAAF4 Tbio Non-IDG -1.67209 48.6 216
Tetratricopeptide repeat protein 30A TTC30A Tdark Non-IDG 0.60 0.00000 57
Stress-induced-phosphoprotein 1 STIP1 Tbio Non-IDG -2.00823 110.8 293