Development Level

Tbio 89 | 10,625
Tdark 67 | 7,003
Tchem 9 | 1,890
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 9 | 633
decreased circulating glucose ... 4 | 121
increased or absent threshold ... 4 | 128
decreased circulating HDL chol... 3 | 77
decreased circulating choleste... 3 | 85
decreased lumbar vertebrae num... 3 | 62
decreased mean corpuscular hem... 3 | 19
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal behavioral response t... 2 | 52
abnormal bone structure 2 | 131
abnormal lens morphology 2 | 73
decreased NK cell number 2 | 16
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased circulating LDL chol... 2 | 37
decreased circulating triglyce... 2 | 83
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
hypoactivity 2 | 89
increased circulating HDL chol... 2 | 63
increased circulating LDL chol... 2 | 15
increased circulating choleste... 2 | 53
increased sacral vertebrae num... 2 | 62
vertebral fusion 2 | 23
abnormal coat/hair pigmentatio... 1 | 54
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal hair growth 1 | 8
abnormal limb position 1 | 3
abnormal maxilla morphology 1 | 16
abnormal pelvic girdle bone mo... 1 | 11
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal vertebrae morphology 1 | 14
abnormal zygomatic bone morpho... 1 | 3
absent pinna reflex 1 | 21
decreased NK T cell number 1 | 28
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating phosphat... 1 | 15
decreased effector memory CD8-... 1 | 24
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased mean corpuscular hem... 1 | 34
decreased prepulse inhibition 1 | 52
decreased red blood cell distr... 1 | 11
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased thoracic vertebrae n... 1 | 7
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased CD4-positive, CD25-p... 1 | 18
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating free fat... 1 | 17
increased circulating magnesiu... 1 | 10
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean platelet volume 1 | 19
increased red blood cell distr... 1 | 21
increased respiratory quotient 1 | 12
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small adrenal glands 1 | 15
thrombocytosis 1 | 23

Disease

ovarian cancer 87 | 8,484
osteosarcoma 76 | 7,933
medulloblastoma, large-cell 58 | 6,234
psoriasis 56 | 6,685
glioblastoma 55 | 5,572
atypical teratoid / rhabdoid tumor 49 | 4,369
lung cancer 37 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,956
astrocytic glioma 29 | 2,241
ependymoma 28 | 2,514
Breast cancer 27 | 3,094
Carcinoma 27 | 2,147
group 3 medulloblastoma 27 | 2,254
invasive ductal carcinoma 26 | 2,950
malignant mesothelioma 26 | 3,162
oligodendroglioma 26 | 2,849
Pick disease 25 | 1,893
pilocytic astrocytoma 25 | 3,086
posterior fossa group B ependymoma 25 | 1,530
lung adenocarcinoma 23 | 2,713
pediatric high grade glioma 23 | 2,712
lung carcinoma 22 | 2,844
Rheumatoid Arthritis 21 | 1,160
primitive neuroectodermal tumor 21 | 3,031
subependymal giant cell astrocytoma 20 | 2,287
adult high grade glioma 19 | 2,148
pancreatic cancer 18 | 2,300
interstitial cystitis 17 | 2,299
juvenile dermatomyositis 17 | 1,189
non-small cell lung cancer 17 | 2,798
progressive supranuclear palsy 17 | 674
Cancer 16 | 2,346
acute quadriplegic myopathy 16 | 1,157
chronic rhinosinusitis 16 | 512
nasopharyngeal carcinoma 16 | 1,056
breast carcinoma 14 | 1,614
cystic fibrosis 14 | 1,665
ulcerative colitis 14 | 2,087
astrocytoma 13 | 1,493
diabetes mellitus 13 | 1,663
non primary Sjogren syndrome sicca 13 | 840
spina bifida 13 | 1,064
Multiple myeloma 12 | 1,327
adrenocortical carcinoma 12 | 1,427
dermatomyositis 12 | 933
ductal carcinoma in situ 12 | 1,745
group 4 medulloblastoma 12 | 1,875
medulloblastoma 12 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
posterior fossa group A ependymoma 12 | 1,511
sonic hedgehog group medulloblastoma 12 | 1,482
Waldenstrons macroglobulinemia 11 | 765
tuberculosis 11 | 1,557
active Crohn's disease 9 | 918
pituitary cancer 9 | 1,972
Ciliopathy 8 | 57
colon cancer 8 | 1,475
cutaneous lupus erythematosus 8 | 1,056
gastric cancer 8 | 430
primary Sjogren syndrome 8 | 789
primary pancreatic ductal adenocarcinoma 8 | 1,271
Alzheimer's disease 7 | 644
Duchenne muscular dystrophy 7 | 602
Neurodegenerative disease 7 | 383
acute myeloid leukemia 7 | 780
Atopic dermatitis 6 | 944
Endometriosis 6 | 535
Obesity 6 | 616
Polydactyly 6 | 93
aldosterone-producing adenoma 6 | 664
atypical teratoid/rhabdoid tumor 6 | 1,095
Down syndrome 5 | 548
Influenza 5 | 142
Intellectual disability 5 | 573
Nephronophthisis 5 | 74
Retinitis pigmentosa 5 | 153
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
hepatocellular carcinoma 5 | 532
pancreatic carcinoma 5 | 567
systemic lupus erythematosus 5 | 156
tuberculosis and treatment for 6 months 5 | 686
Anemia 4 | 252
Asphyxiating thoracic dystrophy 4 | 32
Bardet-Biedl Syndrome 4 | 40
Bipolar Disorder 4 | 266
Fundus dystrophy 4 | 77
Gaucher disease type 1 4 | 171
Jeune thoracic dystrophy 4 | 9
Kidney disease 4 | 396
Neuropathy 4 | 210
Polycystic Ovary Syndrome 4 | 332
Schizophrenia 4 | 501
Senior-Loken syndrome 4 | 21
Sensenbrenner syndrome 4 | 15
esophageal adenocarcinoma 4 | 737
fibroadenoma 4 | 557
hereditary spastic paraplegia 4 | 313
mucosa-associated lymphoid tissue lymphoma 4 | 480

Tissue

Blood and immune system 163 | 17,995
Digestive Tract 163 | 18,473
Endocrine System 163 | 18,512
Female tissues 163 | 18,647
Nervous System 163 | 18,561
Respiratory system 163 | 17,484
Skin and soft tissues 163 | 18,115
Cardiovascular System 162 | 17,958
Liver and Pancreas 162 | 18,136
Male tissues 162 | 17,969
Urinary Tract 162 | 18,444

Target Family

Non-IDG 131 | 11,971
Enzyme 31 | 4,146
Epigenetic 2 | 242
Kinase 2 | 634

UniProt Keyword

TPR repeat 166 | 166
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative tetratricopeptide repeat protein 41 TTC41P Tdark Non-IDG 0.00000 0
Nuclear autoantigenic sperm protein NASP Tbio Non-IDG -1.72078 58.3 103
N-alpha-acetyltransferase 16, NatA auxiliary subunit NAA16 Tbio Enzyme -0.36798 2.36 37
Tetratricopeptide repeat protein 21A TTC21A Tdark Non-IDG -0.36678 2.33 4
Erythroid differentiation-related factor 1 EDRF1 Tdark Non-IDG -0.49732 4.21 41
G-protein-signaling modulator 1 GPSM1 Tbio Non-IDG -1.32467 28.6 99
Tetratricopeptide repeat protein 16 TTC16 Tdark Non-IDG 0.00000 73
Protein unc-45 homolog B UNC45B Tbio Non-IDG -1.52907 38.8 99
Clustered mitochondria protein homolog CLUH Tbio Non-IDG -0.53887 4.52 36
Centrosomal protein of 70 kDa CEP70 Tbio Non-IDG -3.09918 1268.1 97