Development Level

Tbio 5 | 11,651
Tchem 3 | 1,388

IMPC Phenotype

abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
convulsive seizures 1 | 13
increased body length 1 | 32
increased cardiac muscle contr... 1 | 8
increased fasted circulating g... 1 | 76

Disease

Carcinoma 6 | 11,493
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
ulcerative colitis 4 | 1,819
Duchenne muscular dystrophy 3 | 601
Hypertensive disease 3 | 292
adult high grade glioma 3 | 3,801
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
Acquired metabolic disease 2 | 336
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Biliary cirrhosis 2 | 45
Bladder Neoplasm 2 | 112
Cancer 2 | 2,499
Cardiomegaly 2 | 116
Hepatitis B 2 | 108
Hepatitis C 2 | 94
Hepatolenticular Degeneration 2 | 24
Hypertension 2 | 396
Irregular astigmatism 2 | 12
Liver Cirrhosis, Biliary 2 | 33
Liver Cirrhosis, Experimental 2 | 769
Polycystic ovary syndrome 2 | 360
Prenatal Injuries 2 | 11
Urinary Bladder Neoplasms 2 | 114
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cystic fibrosis and chronic rhinosinusitis 2 | 214
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
primary pancreatic ductal adenocarcinoma 2 | 1,109
Allergic hypersensitivity disease 1 | 126
Allergic rhinitis 1 | 95
Aortic Valve Insufficiency 1 | 40
Aortic aneurysm 1 | 38
Arthritis 1 | 290
Barrett's esophagus 1 | 182
Breast Neoplasms 1 | 445
Cardiovascular system disease 1 | 246
Chest Pain 1 | 38
Coronary artery disease 1 | 268
Cutis Laxa 1 | 39
Cutis Laxa, Autosomal Recessive, Type 1A 1 | 3
Cutis Laxa, Autosomal Recessive, Type I 1 | 3
Depressive disorder 1 | 409
Diabetes Mellitus, Experimental 1 | 108
Diabetic Nephropathies 1 | 37
Diabetic Nephropathy 1 | 34
Esophageal Squamous Cell Carcinoma 1 | 77
Exfoliation Syndrome 1 | 12
Gaucher disease type 3 1 | 67
Glaucoma 1 | 239
Keratoconus 1 | 113
Liver Cirrhosis 1 | 181
Mammary Neoplasms 1 | 425
Neoplasm Invasiveness 1 | 161
Neoplastic Cell Transformation 1 | 89
Pigment dispersion syndrome 1 | 11
Pulmonary hypertension 1 | 86
Squamous cell carcinoma of esophagus 1 | 77
West Nile encephalitis 1 | 9
active Crohn's disease 1 | 922
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
fascioscapulohumeral muscular dystrophy 1 | 100
fibroadenoma 1 | 559
head and neck cancer 1 | 271
interstitial lung disease 1 | 298
medulloblastoma 1 | 720
mucosa-associated lymphoid tissue lymphoma 1 | 484
nephrosclerosis 1 | 333
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
posterior fossa group A ependymoma 1 | 468
tuberculosis 1 | 2,010
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Enzyme 8 | 4,145

UniProt Keyword

TPQ 8 | 8
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein-lysine 6-oxidase LOX Tbio Enzyme -3.36257 2227.1 513
Lysyl oxidase homolog 2 LOXL2 Tbio Enzyme -2.24186 173.0 274
Lysyl oxidase homolog 3 LOXL3 Tbio Enzyme -1.24444 16.8 108
Membrane primary amine oxidase AOC3 Tchem Enzyme -2.79843 685.2 285
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.55611 364.6 174
Amiloride-sensitive amine oxidase [copper-containing] AOC1 Tchem Enzyme -2.77629 590.0 271
Retina-specific copper amine oxidase AOC2 Tchem Enzyme -2.26046 183.3 71
Lysyl oxidase homolog 4 LOXL4 Tbio Enzyme -1.36310 22.4 159