Development Level

Tbio 246 | 11,445
Tclin 64 | 613
Tchem 34 | 1,598
Tdark 34 | 6,588

Collection

Ion Channel: IDG Consortium (T... 16 | 99
GPCR: IDG Consortium (Complete... 2 | 25
Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 18 | 979
decreased total body fat amoun... 12 | 207
preweaning lethality, incomple... 12 | 499
abnormal behavior 11 | 298
increased total body fat amoun... 9 | 134
decreased body weight 7 | 161
decreased lymphocyte cell numb... 7 | 83
decreased grip strength 6 | 116
decreased vertical activity 6 | 208
increased lean body mass 6 | 172
abnormal bone structure 5 | 187
decreased circulating choleste... 5 | 93
hyperactivity 5 | 148
increased circulating chloride... 5 | 41
abnormal locomotor behavior 4 | 24
abnormal seminal vesicle morph... 4 | 114
abnormal testis morphology 4 | 43
decreased bone mineral content 4 | 151
decreased circulating HDL chol... 4 | 68
decreased lean body mass 4 | 135
embryonic lethality prior to t... 4 | 278
enlarged heart 4 | 210
increased mean corpuscular vol... 4 | 92
increased monocyte cell number 4 | 63
increased or absent threshold ... 4 | 101
small testis 4 | 58
abnormal behavioral response t... 3 | 66
abnormal epididymis morphology 3 | 42
abnormal heart morphology 3 | 162
abnormal sleep behavior 3 | 70
decreased body length 3 | 101
decreased fasted circulating g... 3 | 65
decreased mean corpuscular vol... 3 | 79
decreased startle reflex 3 | 75
hypoactivity 3 | 132
impaired glucose tolerance 3 | 75
increased bone mineral content 3 | 108
increased circulating alkaline... 3 | 122
increased startle reflex 3 | 112
small superior vagus ganglion 3 | 74
tremors 3 | 39
abnormal bone mineralization 2 | 38
abnormal cecum morphology 2 | 7
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
abnormal gait 2 | 69
abnormal joint morphology 2 | 23
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
abnormal spleen morphology 2 | 55
brachydactyly 2 | 19
convulsive seizures 2 | 13
decreased bone mineral density 2 | 126
decreased circulating alkaline... 2 | 46
decreased circulating phosphat... 2 | 27
decreased circulating triglyce... 2 | 79
decreased exploration in new e... 2 | 11
decreased heart weight 2 | 27
decreased neutrophil cell numb... 2 | 42
decreased pulmonary respirator... 2 | 5
embryonic lethality prior to o... 2 | 239
enlarged cecum 2 | 5
enlarged stomach 2 | 2
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased bone mineral density 2 | 72
increased circulating amylase ... 2 | 25
increased circulating sodium l... 2 | 71
increased heart weight 2 | 62
increased mean corpuscular hem... 2 | 36
increased neutrophil cell numb... 2 | 46
increased red blood cell distr... 2 | 34
increased vertical activity 2 | 24
limb grasping 2 | 41
persistence of hyaloid vascula... 2 | 33
short tibia 2 | 97
small thymus 2 | 16
syndactyly 2 | 23
abnormal hair growth 1 | 10
abnormal head morphology 1 | 10
abnormal liver morphology 1 | 17
abnormal retinal vasculature m... 1 | 27
abnormal tail movements 1 | 12
absent vibrissae 1 | 12
decreased T cell number 1 | 15
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased hematocrit 1 | 46
decreased red blood cell distr... 1 | 41
increased cardiac muscle contr... 1 | 8
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
prenatal lethality 1 | 28
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 287 | 11,493
medulloblastoma, large-cell 237 | 6,241
glioblastoma 220 | 5,792
atypical teratoid / rhabdoid tumor 219 | 5,112
ependymoma 205 | 4,679
adult high grade glioma 181 | 3,801
Astrocytoma, Pilocytic 162 | 3,081
group 3 medulloblastoma 157 | 4,104
oligodendroglioma 156 | 2,850
psoriasis 152 | 6,694
ovarian cancer 151 | 8,520
osteosarcoma 147 | 7,950
primitive neuroectodermal tumor 146 | 3,035
astrocytic glioma 136 | 2,597
Schizophrenia 116 | 1,160
Kidney cancer 110 | 2,613
lung carcinoma 108 | 2,843
subependymal giant cell astrocytoma 103 | 2,287
lung cancer 102 | 4,740
Pick disease 98 | 1,894
Breast cancer 74 | 3,578
pituitary cancer 74 | 1,972
malignant mesothelioma 71 | 3,232
Bipolar Disorder 69 | 666
intraductal papillary-mucinous neoplasm (IPMN) 64 | 3,291
Epilepsy 63 | 792
invasive ductal carcinoma 61 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 59 | 2,955
non-small cell lung cancer 56 | 2,890
Intellectual disability 55 | 1,016
intraductal papillary-mucinous carcinoma (IPMC) 55 | 2,989
Autistic Disorder 48 | 364
interstitial cystitis 48 | 2,312
group 4 medulloblastoma 46 | 1,855
lung adenocarcinoma 46 | 2,716
Liver cancer 44 | 604
pancreatic cancer 44 | 2,398
Alcoholic Intoxication, Chronic 40 | 289
General anesthesia 40 | 53
colon cancer 38 | 1,478
ductal carcinoma in situ 38 | 1,745
tuberculosis 38 | 2,010
Alzheimer's disease 37 | 658
cystic fibrosis 37 | 1,696
Depressive disorder 36 | 409
Parkinson's disease 35 | 392
breast carcinoma 35 | 1,638
Autosomal recessive predisposition 33 | 1,442
Mental Depression 33 | 333
Melanoma 30 | 711
Seizures 30 | 596
astrocytoma 30 | 1,146
Major Depressive Disorder 29 | 301
Muscle hypotonia 29 | 571
ulcerative colitis 28 | 1,819
medulloblastoma 27 | 720
Skin cancer 26 | 469
Tonic-clonic epilepsy 25 | 47
adrenocortical carcinoma 25 | 1,428
pediatric high grade glioma 25 | 1,064
Amyotrophic lateral sclerosis 24 | 451
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
Cancer 23 | 2,499
Dull intelligence 23 | 645
Low intelligence 23 | 645
Mental Retardation 23 | 645
Mental deficiency 23 | 645
Poor school performance 23 | 645
acute quadriplegic myopathy 22 | 1,158
Alcohol dependence 21 | 107
Mood Disorders 21 | 184
Neurodegenerative disease 21 | 414
primary pancreatic ductal adenocarcinoma 21 | 1,109
Anxiety 20 | 136
Local anesthesia 20 | 40
Nicotine dependence 20 | 54
Unipolar Depression 20 | 250
spina bifida 20 | 1,074
Cognitive delay 19 | 608
Global developmental delay 19 | 608
Mental and motor retardation 19 | 608
Rheumatoid arthritis 19 | 1,191
Toxic encephalopathy 19 | 141
active Crohn's disease 19 | 922
active ulcerative colitis 19 | 764
aldosterone-producing adenoma 19 | 665
diabetes mellitus 19 | 1,728
juvenile dermatomyositis 19 | 1,187
non primary Sjogren syndrome sicca 19 | 891
Cocaine-Related Disorders 18 | 92
Down syndrome 18 | 499
Autism spectrum disorder 17 | 101
Endometrial cancer 17 | 311
Infantile onset 17 | 238
Neuropathy 17 | 261
Obesity 17 | 678
progressive supranuclear palsy 17 | 676
cutaneous lupus erythematosus 16 | 1,057
dermatomyositis 16 | 966
gastric carcinoma 16 | 807

Tissue

Endocrine System 369 | 18,159
Nervous System 364 | 16,725
Digestive Tract 357 | 17,369
Female tissues 355 | 17,400
Skin and soft tissues 353 | 17,230
Male tissues 350 | 17,142
Urinary Tract 334 | 16,678
Blood and immune system 333 | 16,909
Liver and Pancreas 333 | 16,750
Respiratory system 317 | 16,393
Cardiovascular System 287 | 15,192

Target Family

Non-IDG 234 | 12,091
Ion Channel 73 | 344
Enzyme 35 | 4,145
GPCR 12 | 408
Kinase 11 | 634
Transporter 10 | 473
Epigenetic 2 | 242
Transcription Factor 1 | 1,400

UniProt Keyword

Synapse 378 | 378
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leucine-rich glioma-inactivated protein 1 LGI1 Tbio Non-IDG -2.52790 342.7 207
Proline-rich membrane anchor 1 PRIMA1 Tbio Non-IDG -2.20803 151.5 6
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
E3 ubiquitin-protein ligase Praja-2 PJA2 Tbio Enzyme -0.64427 3.70 175
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tbio Non-IDG -0.56258 5.05 40
Delphilin GRID2IP Tdark Non-IDG -0.73531 6.97 47
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206
Leucine-rich repeat transmembrane protein FLRT2 FLRT2 Tbio Non-IDG -1.09240 12.6 50