Development Level

Tbio 40 | 10,625
Tdark 8 | 7,003
Tchem 4 | 1,890
Tclin 4 | 602

IMPC Phenotype

preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal gait 1 | 51
abnormal limb morphology 1 | 7
abnormal neural tube morpholog... 1 | 8
abnormal skin appearance 1 | 8
abnormal tail morphology 1 | 17
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased respiratory quotient 1 | 12
decreased total body fat amoun... 1 | 186
edema 1 | 11
embryonic growth retardation 1 | 28
embryonic lethality prior to t... 1 | 187
hypoactivity 1 | 89
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased spleen weight 1 | 3

Disease

ovarian cancer 25 | 8,491
lung cancer 23 | 4,473
osteosarcoma 22 | 7,933
lung carcinoma 21 | 2,844
psoriasis 21 | 6,685
interstitial cystitis 19 | 2,299
Carcinoma 18 | 2,147
glioblastoma 18 | 5,572
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
medulloblastoma, large-cell 18 | 6,234
pilocytic astrocytoma 18 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,289
lung adenocarcinoma 17 | 2,714
non-small cell lung cancer 17 | 2,798
ulcerative colitis 17 | 2,087
malignant mesothelioma 16 | 3,163
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
oligodendroglioma 14 | 2,849
invasive ductal carcinoma 13 | 2,950
pituitary cancer 13 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Cancer 11 | 2,346
adult high grade glioma 11 | 2,148
atypical teratoid / rhabdoid tumor 11 | 4,369
diabetes mellitus 11 | 1,663
group 3 medulloblastoma 11 | 2,254
pancreatic cancer 11 | 2,300
posterior fossa group A ependymoma 11 | 1,511
subependymal giant cell astrocytoma 11 | 2,287
Age related macular degeneration 10 | 84
adrenocortical carcinoma 10 | 1,427
cystic fibrosis 10 | 1,670
ductal carcinoma in situ 10 | 1,745
Breast cancer 9 | 3,098
colon cancer 9 | 1,475
Kidney disease 8 | 397
breast carcinoma 8 | 1,614
dermatomyositis 8 | 966
hemolytic-uremic syndrome 8 | 28
primitive neuroectodermal tumor 8 | 3,031
tuberculosis 8 | 1,563
IGA Glomerulonephritis 7 | 454
Pick disease 7 | 1,893
Rheumatoid Arthritis 7 | 1,170
astrocytic glioma 7 | 2,241
cutaneous lupus erythematosus 7 | 1,056
esophageal adenocarcinoma 7 | 737
group 4 medulloblastoma 7 | 1,875
mucosa-associated lymphoid tissue lymphoma 7 | 480
pediatric high grade glioma 7 | 2,712
Atherosclerosis 6 | 275
Atopic dermatitis 6 | 944
Complement deficiency 6 | 15
Duchenne muscular dystrophy 6 | 602
Multiple Sclerosis 6 | 498
atypical teratoid/rhabdoid tumor 6 | 1,095
ependymoma 6 | 2,514
gastric carcinoma 6 | 832
posterior fossa group B ependymoma 6 | 1,530
primary Sjogren syndrome 6 | 788
primary pancreatic ductal adenocarcinoma 6 | 1,271
Anemia 5 | 252
Atypical Hemolytic Uremic Syndrome 5 | 9
Becker muscular dystrophy 5 | 187
Hypersensitivity reaction type II disease 5 | 235
Thrombocytopenia 5 | 105
acute quadriplegic myopathy 5 | 1,157
fibroadenoma 5 | 557
juvenile dermatomyositis 5 | 1,189
limb girdle muscular dystrophy 2A 5 | 156
medulloblastoma 5 | 1,524
nasopharyngeal carcinoma 5 | 1,056
Alzheimer's disease 4 | 644
Arthritis 4 | 248
Asthma 4 | 349
Coronary artery disease 4 | 240
Down syndrome 4 | 548
Endometriosis 4 | 535
HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1 4 | 6
Macular Degeneration, Age-Related, 1 4 | 9
Peripheral Neuropathy 4 | 303
Vascular disease 4 | 281
Waldenstrons macroglobulinemia 4 | 764
astrocytoma 4 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
sonic hedgehog group medulloblastoma 4 | 1,482
Amyotrophic Lateral Sclerosis 3 | 432
Autistic Disorder 3 | 320
Cerebrovascular disease 3 | 231
Dermatitis 3 | 141
Hypertension 3 | 293
Inflammatory bowel disease 3 | 142
Malaria 3 | 140
Peritonitis 3 | 37
Schizophrenia 3 | 503
Vasculitis 3 | 64
active Crohn's disease 3 | 918
non-small cell lung carcinoma 3 | 413
periodontitis 3 | 269
spina bifida 3 | 1,064

Tissue

Blood and immune system 56 | 17,994
Cardiovascular System 56 | 17,957
Endocrine System 56 | 18,511
Female tissues 56 | 18,646
Liver and Pancreas 56 | 18,135
Male tissues 56 | 17,968
Nervous System 56 | 18,560
Urinary Tract 56 | 18,443
Digestive Tract 55 | 18,472
Respiratory system 55 | 17,483
Skin and soft tissues 54 | 18,114

Target Family

Non-IDG 51 | 11,969
Enzyme 4 | 4,146
GPCR 1 | 408

UniProt Keyword

Sushi 56 | 56
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine-threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E-selectin SELE Tchem Non-IDG -3.43650 2598.8 820
Complement receptor type 1 CR1 Tbio Non-IDG -3.34929 2279.9 502
L-selectin SELL Tchem Non-IDG -3.45880 2781.0 888
Complement factor H-related protein 5 CFHR5 Tbio Non-IDG -1.41720 28.8 88
Membrane cofactor protein CD46 Tbio Non-IDG -2.92514 849.0 564
Pappalysin-2 PAPPA2 Tbio Non-IDG -1.30676 24.1 106
Complement C2 C2 Tbio Non-IDG -2.05345 88.6 180
Coagulation factor XIII B chain F13B Tbio Non-IDG -2.19902 150.8 94
Inactive serine protease PAMR1 PAMR1 Tdark Enzyme -0.85109 6.55 19
C4b-binding protein alpha chain C4BPA Tbio Non-IDG -2.42314 274.1 138