Development Level

Tbio 55 | 11,445
Tchem 29 | 1,598
Tdark 11 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased vertical activity 2 | 208
increased grip strength 2 | 41
increased lean body mass 2 | 172
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal motor learning 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
anophthalmia 1 | 33
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased cardiac muscle contr... 1 | 11
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased heart left ventricle... 1 | 28
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased cardiac stroke volum... 1 | 1
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased heart rate 1 | 23
increased mean corpuscular vol... 1 | 92
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
shortened RR interval 1 | 17
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Carcinoma 61 | 11,493
ovarian cancer 53 | 8,520
osteosarcoma 46 | 7,950
psoriasis 46 | 6,694
glioblastoma 38 | 5,792
lung cancer 38 | 4,740
Cancer 36 | 2,499
medulloblastoma, large-cell 35 | 6,241
atypical teratoid / rhabdoid tumor 32 | 5,112
lung adenocarcinoma 28 | 2,716
Breast cancer 27 | 3,578
non-small cell lung cancer 26 | 2,890
ependymoma 23 | 4,679
group 3 medulloblastoma 23 | 4,104
invasive ductal carcinoma 22 | 2,951
malignant mesothelioma 21 | 3,232
adult high grade glioma 20 | 3,801
oligodendroglioma 20 | 2,850
tuberculosis 20 | 2,010
Astrocytoma, Pilocytic 19 | 3,081
pancreatic cancer 19 | 2,398
breast carcinoma 17 | 1,638
colon cancer 17 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
Kidney cancer 16 | 2,613
Vascular disease 16 | 319
diabetes mellitus 16 | 1,728
ductal carcinoma in situ 16 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
acute quadriplegic myopathy 15 | 1,158
Neurodegenerative disease 14 | 414
Pick disease 14 | 1,894
group 4 medulloblastoma 14 | 1,855
Multiple myeloma 13 | 1,332
Rheumatoid arthritis 13 | 1,191
adrenocortical carcinoma 13 | 1,428
cystic fibrosis 13 | 1,696
pituitary cancer 13 | 1,972
subependymal giant cell astrocytoma 13 | 2,287
astrocytic glioma 12 | 2,597
primitive neuroectodermal tumor 12 | 3,035
dermatomyositis 11 | 966
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
juvenile dermatomyositis 11 | 1,187
lung carcinoma 11 | 2,843
Waldenstrons macroglobulinemia 10 | 765
esophageal adenocarcinoma 9 | 737
fibroadenoma 9 | 559
primary pancreatic ductal adenocarcinoma 9 | 1,109
spina bifida 9 | 1,074
ulcerative colitis 9 | 1,819
astrocytoma 8 | 1,146
non primary Sjogren syndrome sicca 8 | 891
pediatric high grade glioma 8 | 1,064
Alzheimer's disease 7 | 658
Atopic dermatitis 7 | 952
acute myeloid leukemia 7 | 783
chronic rhinosinusitis 7 | 512
interstitial cystitis 7 | 2,312
Autosomal recessive predisposition 6 | 1,442
Parkinson's disease 6 | 392
active Crohn's disease 6 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
gastric cancer 6 | 459
hepatocellular carcinoma 6 | 547
Acquired scoliosis 5 | 281
Amyotrophic lateral sclerosis 5 | 451
Bipolar Disorder 5 | 666
Breast Neoplasms 5 | 445
Curvature of spine 5 | 282
Liver cancer 5 | 604
Mammary Neoplasms 5 | 425
Melanoma 5 | 711
Myocardial Ischemia 5 | 169
Neuropathy 5 | 261
Orbital separation excessive 5 | 244
Osteoporosis 5 | 363
Polycystic ovary syndrome 5 | 360
Prostatic Neoplasms 5 | 495
Schizophrenia 5 | 1,160
Short stature 5 | 531
active ulcerative colitis 5 | 764
aldosterone-producing adenoma 5 | 665
gastric carcinoma 5 | 807
inflammatory breast cancer 5 | 286
pancreatic carcinoma 5 | 562
posterior fossa group A ependymoma 5 | 468
Arthritis 4 | 290
Arthritis, Juvenile 4 | 126
Chronic Lymphocytic Leukemia 4 | 262
Contact Dermatitis 4 | 81
Depressive disorder 4 | 409
Dermatitis, Contact 4 | 71
Down syndrome 4 | 499
Juvenile arthritis 4 | 126
Malaria 4 | 160
medulloblastoma 4 | 720
nasopharyngeal carcinoma 4 | 1,058
progressive supranuclear palsy 4 | 676

Tissue

Blood and immune system 87 | 16,909
Digestive Tract 87 | 17,369
Endocrine System 87 | 18,159
Female tissues 87 | 17,400
Liver and Pancreas 87 | 16,750
Male tissues 87 | 17,142
Nervous System 87 | 16,725
Respiratory system 87 | 16,393
Skin and soft tissues 87 | 17,230
Urinary Tract 87 | 16,678
Cardiovascular System 84 | 15,192

Target Family

Non-IDG 57 | 12,091
Kinase 21 | 634
Enzyme 10 | 4,145
Transcription Factor 6 | 1,400
GPCR 1 | 408

UniProt Keyword

Stress response 95 | 95
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable G-protein coupled receptor 132 GPR132 Tchem GPCR -2.72228 494.8 185
Heat shock 70 kDa protein 4L HSPA4L Tbio Non-IDG -1.00800 11.5 123
Transmembrane protein 204 TMEM204 Tbio Non-IDG -0.59045 4.13 52
Hypoxia-inducible lipid droplet-associated protein HILPDA Tbio Non-IDG -1.24205 21.6 18
Intraflagellar transport protein 25 homolog HSPB11 Tbio Non-IDG -1.40552 26.1 61
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Teneurin-1 TENM1 Tbio Non-IDG -1.81805 61.8 60
Heat shock-related 70 kDa protein 2 HSPA2 Tbio Non-IDG -1.98655 104.3 162
Mitogen-activated protein kinase kinase kinase kinase 2 MAP4K2 Tchem Kinase -1.60423 35.3 193
Endoribonuclease ZC3H12A ZC3H12A Tbio Enzyme -1.81028 77.8 134