Development Level

Tbio 24 | 11,651
Tchem 6 | 1,388
Tclin 4 | 612
Tdark 1 | 6,593

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal behavior 3 | 298
hyperactivity 3 | 148
decreased bone mineral density 2 | 126
decreased circulating amylase ... 2 | 28
increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal forelimb morphology 1 | 2
abnormal gait 1 | 69
abnormal locomotor activation 1 | 16
abnormal response to new envir... 1 | 10
abnormal testis morphology 1 | 43
corneal vascularization 1 | 6
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased brain size 1 | 4
decreased circulating glycerol... 1 | 16
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating aspartat... 1 | 15
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
shortened QRS complex duration 1 | 1
small epididymis 1 | 3
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small testis 1 | 58
small thymus 1 | 16
thrombocytopenia 1 | 56

Disease

Neurodegenerative disease 34 | 414
Autosomal dominant cerebellar ataxia 30 | 33
Carcinoma 30 | 11,493
Cerebellar Ataxia 20 | 304
ovarian cancer 20 | 8,520
Spinocerebellar Ataxias 19 | 34
atypical teratoid / rhabdoid tumor 18 | 5,112
ependymoma 18 | 4,679
glioblastoma 18 | 5,792
Dysarthria 15 | 192
group 3 medulloblastoma 15 | 4,104
medulloblastoma, large-cell 15 | 6,241
Atrophy of cerebellum 14 | 103
Cerebellar degeneration 14 | 103
Infratentorial atrophy 14 | 103
adult high grade glioma 14 | 3,801
oligodendroglioma 14 | 2,850
psoriasis 13 | 6,694
Ataxia, Appendicular 12 | 25
lung cancer 12 | 4,740
osteosarcoma 12 | 7,950
Gait Ataxia 11 | 51
Cerebellar Dysmetria 10 | 56
Deglutition Disorders 10 | 132
Intellectual disability 10 | 1,016
Kidney cancer 10 | 2,613
Progressive cerebellar ataxia 10 | 13
astrocytic glioma 10 | 2,597
malignant mesothelioma 10 | 3,232
primitive neuroectodermal tumor 10 | 3,035
Astrocytoma, Pilocytic 9 | 3,081
Ataxia, Spinocerebellar 9 | 16
Breast cancer 9 | 3,578
lung carcinoma 9 | 2,843
Hyperreflexia 8 | 209
Slow progression 8 | 89
Depressive disorder 7 | 409
Dysdiadochokinesis 7 | 25
Epilepsy 7 | 792
Schizophrenia 7 | 1,160
colon cancer 7 | 1,478
dentatorubral-pallidoluysian atrophy 7 | 21
Babinski Reflex 6 | 100
Dysmetric saccades 6 | 9
Nystagmus 6 | 317
Nystagmus, End-Position 6 | 12
Progressive disorder 6 | 142
Slowed saccades 6 | 12
invasive ductal carcinoma 6 | 2,951
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
Ataxia, Truncal 5 | 21
Dementia 5 | 175
Machado-Joseph disease 5 | 18
Multiple myeloma 5 | 1,332
Myoclonus 5 | 74
Pick disease 5 | 1,894
Waldenstrons macroglobulinemia 5 | 765
acute quadriplegic myopathy 5 | 1,158
dermatomyositis 5 | 966
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
Abnormal coordination 4 | 15
Abnormal visual pursuit 4 | 14
Alzheimer's disease 4 | 658
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Cancer 4 | 2,499
Choreatic disease 4 | 52
Decreased vibratory sense 4 | 7
Dystonia 4 | 164
Impaired horizontal smooth pursuit 4 | 6
Impaired smooth pursuit 4 | 14
Liver cancer 4 | 604
Movement Disorders 4 | 55
Muscle Spasticity 4 | 195
Muscle hypotonia 4 | 571
Parkinson's disease 4 | 392
Seizures 4 | 596
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
Amyotrophic lateral sclerosis 3 | 451
Atopic dermatitis 3 | 952
Bradykinesia 3 | 34
Chorea 3 | 29
Decreased tendon reflex 3 | 122
Dystonic disease 3 | 106
Huntington's disease 3 | 76
Multiple Sclerosis 3 | 540
Neuropathy 3 | 261
Peripheral sensorimotor neuropathy 3 | 16
active ulcerative colitis 3 | 764
non-small cell lung cancer 3 | 2,890
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074

Tissue

Blood and immune system 34 | 16,909
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Skin and soft tissues 33 | 17,230
Respiratory system 32 | 16,393
Urinary Tract 32 | 16,678
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 7 | 4,145
Ion Channel 6 | 344
Kinase 3 | 634

UniProt Keyword

Spinocerebellar ataxia 35 | 35
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Short transient receptor potential channel 3 TRPC3 Tchem Ion Channel -2.46704 294.6 217
Ataxin-2 ATXN2 Tbio Non-IDG -2.32523 224.6 194
Sorting nexin-14 SNX14 Tbio Non-IDG -0.86091 6.82 56
Proenkephalin-B PDYN Tbio Non-IDG -3.48486 3009.3 172
Disabled homolog 1 DAB1 Tbio Non-IDG -0.36015 2.98 395
Neprilysin MME Tclin Enzyme -3.64168 4375.8 1505
Tripeptidyl-peptidase 1 TPP1 Tbio Enzyme -2.18323 155.2 273
Ataxin-7 ATXN7 Tbio Non-IDG -2.33556 232.9 120
Elongation factor 2 EEF2 Tbio Non-IDG -2.95619 938.4 363
Fibroblast growth factor 14 FGF14 Tbio Non-IDG -1.64659 46.1 116