Development Level

Tbio 20 | 10,625
Tchem 9 | 1,890
Tclin 3 | 602
Tdark 1 | 7,003

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

decreased bone mineral density 3 | 126
decreased lean body mass 2 | 195
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal forelimb morphology 1 | 2
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal locomotor activation 1 | 26
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal response to new envir... 1 | 8
abnormal rib morphology 1 | 28
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
corneal vascularization 1 | 5
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased brain size 1 | 4
decreased circulating amylase ... 1 | 24
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating glycerol... 1 | 19
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased circulating aspartat... 1 | 17
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
limb grasping 1 | 35
no abnormal phenotype detected 1 | 3
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small epididymis 1 | 3
small heart 1 | 8
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small stomach 1 | 3
small testis 1 | 37
small thymus 1 | 11
thrombocytopenia 1 | 46

Disease

Neurodegenerative disease 32 | 383
Autosomal dominant cerebellar ataxia 29 | 34
Cerebellar Ataxia 20 | 72
ovarian cancer 20 | 8,484
glioblastoma 15 | 5,572
medulloblastoma, large-cell 14 | 6,234
oligodendroglioma 13 | 2,849
psoriasis 13 | 6,685
atypical teratoid / rhabdoid tumor 12 | 4,369
ependymoma 11 | 2,514
Intellectual disability 10 | 573
osteosarcoma 10 | 7,933
primitive neuroectodermal tumor 10 | 3,031
Ataxia, Spinocerebellar 9 | 15
group 3 medulloblastoma 9 | 2,254
lung cancer 9 | 4,466
malignant mesothelioma 9 | 3,162
pilocytic astrocytoma 9 | 3,086
Carcinoma 8 | 2,147
adult high grade glioma 8 | 2,148
astrocytic glioma 8 | 2,241
lung carcinoma 8 | 2,844
pediatric high grade glioma 8 | 2,712
Breast cancer 7 | 3,094
dentatorubral-pallidoluysian atrophy 7 | 21
colon cancer 6 | 1,475
tuberculosis 6 | 1,557
Epilepsy 5 | 346
Machado-Joseph disease 5 | 18
Multiple myeloma 5 | 1,327
Pick disease 5 | 1,893
Waldenstrons macroglobulinemia 5 | 765
astrocytoma 5 | 1,493
atypical teratoid/rhabdoid tumor 5 | 1,095
dermatomyositis 5 | 933
invasive ductal carcinoma 5 | 2,950
sonic hedgehog group medulloblastoma 5 | 1,482
subependymal giant cell astrocytoma 5 | 2,287
Alzheimer's disease 4 | 644
Parkinson's disease 4 | 364
acute quadriplegic myopathy 4 | 1,157
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
lung adenocarcinoma 4 | 2,713
ulcerative colitis 4 | 2,087
Amyotrophic Lateral Sclerosis 3 | 431
Ataxic cerebral palsy 3 | 4
Atopic dermatitis 3 | 944
Cancer 3 | 2,346
Dystonia 3 | 77
Friedreich ataxia 3 | 23
Huntington's disease 3 | 72
Multiple Sclerosis 3 | 498
Olivopontocerebellar atrophy 3 | 9
PARKINSON DISEASE, LATE-ONSET 3 | 18
Rheumatoid Arthritis 3 | 1,160
Spinocerebellar ataxia type 1 3 | 16
Spinocerebellar ataxia type 2 3 | 19
breast carcinoma 3 | 1,614
cystic fibrosis 3 | 1,665
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
medulloblastoma 3 | 1,524
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 1,511
posterior fossa group B ependymoma 3 | 1,530
spina bifida 3 | 1,064
Blindness 2 | 84
Brain disease 2 | 83
Celiac disease 2 | 112
Choreatic disease 2 | 27
Eaton-Lambert syndrome 2 | 40
Hyperalgesia 2 | 71
Kennedy's disease 2 | 13
Malignant neoplasm of breast 2 | 63
Obesity 2 | 616
Paraplegia 2 | 71
Peripheral Neuropathy 2 | 303
Prostatic Neoplasms 2 | 471
SPINOCEREBELLAR ATAXIA 21 2 | 2
active Crohn's disease 2 | 918
adrenocortical carcinoma 2 | 1,427
chronic rhinosinusitis 2 | 512
cystic fibrosis and chronic rhinosinusitis 2 | 213
diabetes mellitus 2 | 1,663
gastric carcinoma 2 | 832
glioblastoma multiforme 2 | 347
juvenile dermatomyositis 2 | 1,189
non primary Sjogren syndrome sicca 2 | 840
non-small cell lung cancer 2 | 2,798
pancreatic cancer 2 | 2,300
progressive supranuclear palsy 2 | 674
Bradycardia 1 | 24
Hypotension 1 | 53
Myotonic dystrophy type 1 1 | 16
Pain 1 | 70
Phenylketonuria 1 | 18
Restless legs syndrome 1 | 28
Spinocerebellar ataxia type 17 1 | 7
Spinocerebellar ataxia type 8 1 | 5

Tissue

Blood and immune system 32 | 17,995
Cardiovascular System 32 | 17,958
Digestive Tract 32 | 18,473
Endocrine System 32 | 18,512
Female tissues 32 | 18,647
Liver and Pancreas 32 | 18,136
Nervous System 32 | 18,561
Respiratory system 32 | 17,484
Skin and soft tissues 32 | 18,115
Urinary Tract 32 | 18,444
Male tissues 31 | 17,969

Target Family

Non-IDG 18 | 11,971
Enzyme 6 | 4,146
Ion Channel 6 | 341
Kinase 3 | 634

UniProt Keyword

Spinocerebellar ataxia 33 | 33
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein BEAN1 BEAN1 Tbio Non-IDG -1.84308 76.0 68
Elongation of very long chain fatty acids protein 5 ELOVL5 Tchem Non-IDG -1.81279 72.3 189
Elongation factor 2 EEF2 Tchem Non-IDG -2.93803 911.5 347
Ataxin-7 ATXN7 Tbio Non-IDG -2.31354 225.6 109
Spectrin beta chain, non-erythrocytic 2 SPTBN2 Tbio Non-IDG -1.67039 49.6 123
Protein-glutamine gamma-glutamyltransferase 6 TGM6 Tchem Enzyme -2.00555 102.6 48
Proenkephalin-B PDYN Tbio Non-IDG -3.47467 2966.3 161
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.30673 205.2 153
AFG3-like protein 2 AFG3L2 Tbio Enzyme -1.52125 36.4 129
Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G Tclin Ion Channel -2.12262 130.4 196