Development Level

Tbio 54 | 10,625
Tclin 29 | 602
Tchem 18 | 1,890
Tdark 16 | 7,003

Collection

Eligible Ion Channel Proteins 8 | 117

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal bone structure 4 | 131
decreased bone mineral content 4 | 157
decreased total body fat amoun... 4 | 186
abnormal retina morphology 3 | 100
decreased bone mineral density 3 | 126
decreased lean body mass 3 | 195
impaired glucose tolerance 3 | 52
increased circulating alkaline... 3 | 119
increased grip strength 3 | 83
preweaning lethality, incomple... 3 | 260
abnormal eye morphology 2 | 38
abnormal retinal pigmentation 2 | 61
decreased body length 2 | 108
decreased circulating alkaline... 2 | 41
decreased circulating serum al... 2 | 79
decreased fasted circulating g... 2 | 49
decreased hemoglobin content 2 | 53
decreased rib number 2 | 59
increased circulating sodium l... 2 | 71
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal coat appearance 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal cranium morphology 1 | 32
abnormal femur morphology 1 | 14
abnormal incisor color 1 | 2
abnormal iris morphology 1 | 12
abnormal iris transilluminatio... 1 | 1
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal pelvic girdle bone mo... 1 | 11
abnormal response to tactile s... 1 | 16
abnormal spine curvature 1 | 7
abnormal startle reflex 1 | 14
absent pinna reflex 1 | 21
absent vibrissae 1 | 14
cataract 1 | 26
decreased CD4-positive, CD25-p... 1 | 24
decreased NK cell number 1 | 16
decreased body weight 1 | 174
decreased circulating amylase ... 1 | 24
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating free fat... 1 | 39
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
enlarged thymus 1 | 4
eyelids fail to open 1 | 2
hydrometra 1 | 13
hyperactivity 1 | 108
impaired righting response 1 | 19
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating amylase ... 1 | 13
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased circulating triglyce... 1 | 24
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
kyphosis 1 | 5
small superior vagus ganglion 1 | 20
sparse hair 1 | 6
thrombocytosis 1 | 23
trunk curl 1 | 15

Disease

glioblastoma 43 | 5,572
medulloblastoma, large-cell 43 | 6,234
osteosarcoma 41 | 7,933
psoriasis 39 | 6,685
ovarian cancer 37 | 8,484
atypical teratoid / rhabdoid tumor 30 | 4,369
Carcinoma 29 | 2,147
ependymoma 27 | 2,514
lung carcinoma 27 | 2,844
lung cancer 26 | 4,466
primitive neuroectodermal tumor 25 | 3,031
oligodendroglioma 24 | 2,849
pediatric high grade glioma 23 | 2,712
pilocytic astrocytoma 23 | 3,086
pituitary cancer 23 | 1,972
subependymal giant cell astrocytoma 21 | 2,287
Epilepsy 20 | 346
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
Breast cancer 19 | 3,094
lung adenocarcinoma 19 | 2,713
Atrial Fibrillation 18 | 110
astrocytic glioma 18 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
malignant mesothelioma 18 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
Pick disease 16 | 1,893
interstitial cystitis 16 | 2,299
sonic hedgehog group medulloblastoma 16 | 1,482
non-small cell lung cancer 15 | 2,798
invasive ductal carcinoma 14 | 2,950
adult high grade glioma 13 | 2,148
colon cancer 13 | 1,475
Chronic heart failure 12 | 46
atypical teratoid/rhabdoid tumor 12 | 1,095
ulcerative colitis 12 | 2,087
Edema 11 | 38
Metabolic acidosis 11 | 49
cystic fibrosis 11 | 1,665
ductal carcinoma in situ 11 | 1,745
group 4 medulloblastoma 11 | 1,875
nephrosclerosis 11 | 329
pancreatic cancer 11 | 2,300
posterior fossa group A ependymoma 11 | 1,511
Cough 10 | 21
Dysuria 10 | 24
Epilepsy characterized by intractable complex partial seizures 10 | 28
Hypertension 10 | 287
Itching of skin 10 | 19
Lennox-Gastaut syndrome 10 | 34
Life-Threatening Ventricular Tachycardia 10 | 15
Local anesthesia 10 | 40
Localization-related epilepsy 10 | 13
Minor Skin Wound Pain 10 | 12
Motor cortex epilepsy 10 | 10
Mouth Irritation 10 | 12
Partial seizure 10 | 15
Prevent Minor Bacterial Skin Infection 10 | 10
Skin irritation 10 | 12
Sore throat symptom 10 | 12
Suppression of the Gag Reflex 10 | 12
Tinea Infections 10 | 10
Tinea corporis 10 | 25
Tinea pedis 10 | 30
Tonic-clonic epilepsy 10 | 47
Urinary Tract Irritation 10 | 24
Ventricular arrhythmia 10 | 14
group 3 medulloblastoma 10 | 2,254
Cancer 9 | 2,346
Kidney disease 9 | 396
Status Epilepticus 9 | 85
non primary Sjogren syndrome sicca 9 | 840
Anesthesia for cesarean section 8 | 8
Autistic Disorder 8 | 320
Bipolar disorder in remission 8 | 19
Congestive heart failure 8 | 30
Hypertensive disease 8 | 193
Hypertensive disorder 8 | 58
Major Nerve Block for Surgery 8 | 8
Poisoning by digitalis glycoside 8 | 8
Regional Anesthesia for Labor Pain 8 | 9
Regional Anesthesia for Postoperative Pain 8 | 9
Regional Anesthesia for Surgery 8 | 9
Simple partial seizure 8 | 26
Tonic-clonic seizure 8 | 11
diabetes mellitus 8 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
posterior fossa group B ependymoma 8 | 1,530
tuberculosis 8 | 1,557
Administration of Local Anesthetic Nerve Block 7 | 14
Brugada syndrome 7 | 26
Intellectual disability 7 | 573
Local Anesthesia for Ophthalmologic Procedure 7 | 7
Local anesthesia, by infiltration 7 | 14
Local anesthetic intrathecal block 7 | 7
Postherpetic neuralgia 7 | 12
Premature ejaculation 7 | 16
Prevention of Seizures following Cranial Trauma or Surgery 7 | 7
active Crohn's disease 7 | 918
astrocytoma 7 | 1,493
medulloblastoma 7 | 1,524

Tissue

Digestive Tract 117 | 18,473
Endocrine System 117 | 18,512
Female tissues 117 | 18,647
Nervous System 117 | 18,561
Skin and soft tissues 117 | 18,115
Liver and Pancreas 116 | 18,136
Urinary Tract 116 | 18,444
Blood and immune system 115 | 17,995
Cardiovascular System 114 | 17,958
Male tissues 112 | 17,969
Respiratory system 112 | 17,484

Target Family

Transporter 84 | 473
Ion Channel 29 | 341
Non-IDG 3 | 11,971
Enzyme 1 | 4,146

UniProt Keyword

Sodium transport 117 | 117
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 13 member 1 SLC13A1 Tbio Transporter -1.70334 62.7 18
Sodium/hydrogen exchanger 4 SLC9A4 Tdark Transporter -1.25841 17.4 6
Ileal sodium/bile acid cotransporter SLC10A2 Tchem Transporter -2.60727 417.5 121
Sodium/calcium exchanger 2 SLC8A2 Tbio Transporter -1.56223 31.9 51
Sodium-dependent phosphate transporter 2 SLC20A2 Tbio Transporter -2.18737 165.3 97
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -1.97274 103.1 38
Amiloride-sensitive sodium channel subunit beta SCNN1B Tclin Ion Channel -1.69464 46.7 245
Amiloride-sensitive sodium channel subunit delta SCNN1D Tbio Ion Channel -0.97159 8.72 179
Amiloride-sensitive sodium channel subunit gamma SCNN1G Tclin Ion Channel -2.03787 117.0 162
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.04732 117.9 108