Development Level

Tbio 64 | 11,651
Tclin 30 | 612
Tdark 15 | 6,593
Tchem 11 | 1,388

Collection

Ion Channel: IDG Consortium (T... 7 | 99
RFA-RM-18-021 7 | 328

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal bone structure 5 | 187
decreased bone mineral content 4 | 151
decreased bone mineral density 4 | 126
preweaning lethality, incomple... 4 | 499
abnormal sleep behavior 3 | 70
decreased body length 3 | 101
decreased circulating alkaline... 3 | 46
decreased circulating serum al... 3 | 82
decreased hemoglobin content 3 | 68
decreased prepulse inhibition 3 | 82
impaired glucose tolerance 3 | 75
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased lymphocyte cell numb... 2 | 83
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
enlarged heart 2 | 210
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased grip strength 2 | 41
increased monocyte cell number 2 | 63
short tibia 2 | 97
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal incisor color 1 | 3
abnormal iris morphology 1 | 13
abnormal iris transilluminatio... 1 | 2
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal spine curvature 1 | 9
abnormal startle reflex 1 | 15
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
cataract 1 | 92
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased urine creatinine lev... 1 | 3
embryonic lethality prior to t... 1 | 278
enlarged thymus 1 | 5
eyelids fail to open 1 | 3
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
kyphosis 1 | 5
prenatal lethality prior to he... 1 | 87
prolonged QRS complex duration 1 | 8
small spleen 1 | 19
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27

Disease

Carcinoma 97 | 11,493
glioblastoma 45 | 5,792
medulloblastoma, large-cell 44 | 6,241
osteosarcoma 43 | 7,950
atypical teratoid / rhabdoid tumor 42 | 5,112
ependymoma 41 | 4,679
psoriasis 40 | 6,694
ovarian cancer 38 | 8,520
adult high grade glioma 32 | 3,801
lung cancer 32 | 4,740
Kidney cancer 31 | 2,613
group 3 medulloblastoma 28 | 4,104
lung carcinoma 27 | 2,843
Epilepsy 26 | 792
primitive neuroectodermal tumor 25 | 3,035
Astrocytoma, Pilocytic 24 | 3,081
oligodendroglioma 24 | 2,850
Breast cancer 23 | 3,578
pituitary cancer 23 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
subependymal giant cell astrocytoma 21 | 2,287
astrocytic glioma 20 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
lung adenocarcinoma 19 | 2,716
Atrial Fibrillation 18 | 124
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
malignant mesothelioma 18 | 3,232
Autosomal recessive predisposition 17 | 1,442
interstitial cystitis 17 | 2,312
Metabolic acidosis 16 | 90
Pick disease 16 | 1,894
Seizures 16 | 596
invasive ductal carcinoma 15 | 2,951
non-small cell lung cancer 15 | 2,890
Melanoma 14 | 711
colon cancer 14 | 1,478
pancreatic cancer 14 | 2,398
Hypertension 13 | 396
Chronic heart failure 12 | 46
cystic fibrosis 12 | 1,696
ductal carcinoma in situ 12 | 1,745
Diarrhea 11 | 253
Edema 11 | 81
Intellectual disability 11 | 1,016
Kidney disease 11 | 430
Skin cancer 11 | 469
nephrosclerosis 11 | 333
ulcerative colitis 11 | 1,819
Cognitive delay 10 | 608
Cough 10 | 25
Dysuria 10 | 26
Epilepsy characterized by intractable complex partial seizures 10 | 28
Global developmental delay 10 | 608
Itching of skin 10 | 18
Lennox-Gastaut syndrome 10 | 34
Life-Threatening Ventricular Tachycardia 10 | 15
Local anesthesia 10 | 40
Localization-related epilepsy 10 | 13
Mental and motor retardation 10 | 608
Minor Skin Wound Pain 10 | 12
Motor cortex epilepsy 10 | 10
Mouth Irritation 10 | 12
Partial seizure 10 | 15
Prevent Minor Bacterial Skin Infection 10 | 10
Skin irritation 10 | 12
Sore throat symptom 10 | 12
Status Epilepticus 10 | 98
Suppression of the Gag Reflex 10 | 12
Tinea Infections 10 | 10
Tinea corporis 10 | 25
Tinea pedis 10 | 29
Tonic-clonic epilepsy 10 | 47
Urinary Tract Irritation 10 | 24
Ventricular arrhythmia 10 | 27
Autistic Disorder 9 | 364
Cancer 9 | 2,499
Congestive heart failure 9 | 113
Infantile onset 9 | 238
Liver cancer 9 | 604
Muscle hypotonia 9 | 571
active ulcerative colitis 9 | 764
non primary Sjogren syndrome sicca 9 | 891
tuberculosis 9 | 2,010
Anesthesia for cesarean section 8 | 8
Bipolar Disorder 8 | 666
Cerebellar Ataxia 8 | 304
Constipation 8 | 181
Dyschezia 8 | 135
Failure to gain weight 8 | 365
Hypertensive disease 8 | 292
Major Nerve Block for Surgery 8 | 8
Pediatric failure to thrive 8 | 365
Regional Anesthesia for Labor Pain 8 | 9
Regional Anesthesia for Postoperative Pain 8 | 9
Regional Anesthesia for Surgery 8 | 9
Simple partial seizure 8 | 26
Tonic-clonic seizure 8 | 11
active Crohn's disease 8 | 922
diabetes mellitus 8 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962

Tissue

Endocrine System 116 | 18,159
Digestive Tract 111 | 17,369
Urinary Tract 110 | 16,678
Female tissues 109 | 17,400
Liver and Pancreas 108 | 16,750
Male tissues 108 | 17,142
Skin and soft tissues 108 | 17,230
Nervous System 107 | 16,725
Respiratory system 104 | 16,393
Blood and immune system 100 | 16,909
Cardiovascular System 80 | 15,192

Target Family

Transporter 85 | 473
Ion Channel 31 | 344
Non-IDG 3 | 12,091
Enzyme 1 | 4,145

UniProt Keyword

Sodium transport 120 | 120
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Sodium channel protein type 2 subunit alpha SCN2A Tclin Ion Channel -3.11580 1268.8 107
Sodium/hydrogen exchanger 5 SLC9A5 Tbio Transporter -1.15040 17.1 43
Sodium/myo-inositol cotransporter 2 SLC5A11 Tchem Transporter -1.76250 46.1 82
Amiloride-sensitive sodium channel subunit gamma SCNN1G Tclin Ion Channel -2.10269 131.1 212
Solute carrier family 13 member 5 SLC13A5 Tchem Transporter -1.70063 50.0 86
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -2.00898 110.3 57
Sodium/potassium/calcium exchanger 5 SLC24A5 Tbio Transporter -1.63611 43.9 61
Sodium/potassium-transporting ATPase subunit beta-2 ATP1B2 Tclin Transporter -1.36427 23.9 176
Solute carrier family 22 member 5 SLC22A5 Tbio Transporter -2.47467 297.1 113