Development Level

Tbio 11 | 11,445

IMPC Phenotype

abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal liver size 1 | 5
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal thymus morphology 1 | 7
abnormal urinary bladder morph... 1 | 11
decreased bone mineral density 1 | 126
decreased circulating serum al... 1 | 82
decreased prepulse inhibition 1 | 82
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
preweaning lethality, complete... 1 | 979
small seminal vesicle 1 | 10
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

ovarian cancer 7 | 8,520
Multiple myeloma 5 | 1,332
Carcinoma 4 | 11,493
osteosarcoma 4 | 7,950
Waldenstrons macroglobulinemia 3 | 765
Astrocytoma, Pilocytic 2 | 3,081
Pick disease 2 | 1,894
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
oligodendroglioma 2 | 2,850
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
Allergic hypersensitivity disease 1 | 126
Alzheimer's disease 1 | 658
Ascariasis 1 | 7
Asthma 1 | 385
Cancer 1 | 2,499
Carcinoma, Hepatocellular 1 | 228
Decubitus ulcer 1 | 13
Disease Progression 1 | 136
Endometriosis 1 | 540
Familial hypocalciuric hypercalcemia 1 | 20
HIV Infections 1 | 102
Hepatomegaly 1 | 285
Hereditary renal cell carcinoma 1 | 3
Liver carcinoma 1 | 240
Persistent hyperplastic primary vitreous 1 | 20
Restrictive cardiomyopathy 1 | 11
Rhinitis 1 | 54
Scabies 1 | 7
Schizophrenia 1 | 1,160
Smith-Magenis syndrome 1 | 29
Stevens-Johnson syndrome 1 | 92
Stomach Neoplasms 1 | 300
acute quadriplegic myopathy 1 | 1,158
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
diabetes mellitus 1 | 1,728
group 3 medulloblastoma 1 | 4,104
hereditary spastic paraplegia 1 | 318
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
medulloblastoma 1 | 720
pancreatic cancer 1 | 2,398
pancreatic ductal carcinoma 1 | 11
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 11 | 12,091

UniProt Keyword

Signalosome 11 | 11
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
COP9 signalosome complex subunit 4 COPS4 Tbio Non-IDG -0.91181 7.39 88
COP9 signalosome complex subunit 9 COPS9 Tbio Non-IDG 0.21 0.92 14
COP9 signalosome complex subunit 7a COPS7A Tbio Non-IDG -1.50943 32.2 154
COP9 signalosome complex subunit 1 GPS1 Tbio Non-IDG -1.62973 42.8 246
COP9 signalosome complex subunit 3 COPS3 Tbio Non-IDG -1.12537 14.2 217
COP9 signalosome complex subunit 8 COPS8 Tbio Non-IDG -1.20410 15.8 166
COP9 signalosome complex subunit 2 COPS2 Tbio Non-IDG -0.95832 9.06 329
Protein TESPA1 TESPA1 Tbio Non-IDG -0.73684 6.43 43
COP9 signalosome complex subunit 5 COPS5 Tbio Non-IDG -2.26989 213.6 374
COP9 signalosome complex subunit 7b COPS7B Tbio Non-IDG 0.15 0.83 67