Development Level

Tbio 2,002 | 10,625
Tdark 885 | 7,003
Tchem 423 | 1,890
Tclin 177 | 602

Collection

Eligible Ion Channel Proteins 41 | 117
Eligible non-olfactory GPCR Proteins 21 | 143
Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, complete... 59 | 633
preweaning lethality, incomple... 45 | 260
enlarged heart 36 | 111
decreased total body fat amoun... 30 | 186
abnormal behavior 27 | 226
decreased lean body mass 26 | 195
decreased bone mineral content 25 | 157
decreased grip strength 24 | 123
decreased circulating glucose ... 23 | 121
increased or absent threshold ... 22 | 128
decreased bone mineral density 21 | 126
short tibia 21 | 82
abnormal bone structure 20 | 131
abnormal seminal vesicle morph... 19 | 47
decreased circulating insulin ... 19 | 75
decreased body weight 18 | 174
increased lean body mass 18 | 107
abnormal heart morphology 17 | 51
hypoactivity 16 | 89
increased circulating alkaline... 16 | 119
impaired glucose tolerance 15 | 52
increased circulating HDL chol... 15 | 63
decreased circulating serum al... 14 | 79
embryonic lethality prior to t... 14 | 187
increased mean corpuscular vol... 14 | 91
abnormal sleep behavior 13 | 63
decreased body length 13 | 108
decreased circulating triglyce... 13 | 83
improved glucose tolerance 13 | 56
increased mean corpuscular hem... 13 | 93
abnormal coat/hair pigmentatio... 12 | 54
abnormal embryo size 12 | 112
abnormal lens morphology 12 | 73
abnormal retina morphology 12 | 100
decreased heart weight 12 | 44
hyperactivity 12 | 108
increased bone mineral content 12 | 92
increased grip strength 12 | 83
decreased circulating HDL chol... 11 | 77
decreased circulating choleste... 11 | 85
decreased prepulse inhibition 11 | 52
increased blood urea nitrogen ... 11 | 44
increased bone mineral density 11 | 52
increased circulating sodium l... 11 | 71
increased exploration in new e... 11 | 56
increased hemoglobin content 11 | 45
small testis 11 | 37
abnormal kidney morphology 10 | 30
decreased circulating alanine ... 10 | 53
enlarged epididymis 10 | 27
increased fasted circulating g... 10 | 68
tremors 10 | 34
abnormal QRS complex 9 | 25
abnormal behavioral response t... 9 | 52
abnormal gait 9 | 51
abnormal retinal pigmentation 9 | 61
abnormal testis morphology 9 | 30
decreased fasted circulating g... 9 | 49
decreased hemoglobin content 9 | 53
decreased leukocyte cell numbe... 9 | 54
decreased rib number 9 | 59
increased circulating choleste... 9 | 53
thrombocytopenia 9 | 46
abnormal spleen morphology 8 | 36
decreased circulating free fat... 8 | 39
decreased erythrocyte cell num... 8 | 43
decreased monocyte cell number 8 | 28
increased leukocyte cell numbe... 8 | 37
increased total body fat amoun... 8 | 57
abnormal bone mineralization 7 | 55
abnormal epididymis morphology 7 | 31
abnormal eye morphology 7 | 38
abnormal tail morphology 7 | 17
decreased circulating total pr... 7 | 41
decreased eosinophil cell numb... 7 | 41
decreased lumbar vertebrae num... 7 | 62
decreased mean corpuscular vol... 7 | 50
decreased startle reflex 7 | 48
female infertility 7 | 34
increased circulating potassiu... 7 | 31
increased hematocrit 7 | 36
abnormal skin morphology 6 | 23
abnormal vibrissa morphology 6 | 17
decreased caudal vertebrae num... 6 | 49
decreased circulating creatini... 6 | 31
embryonic lethality prior to o... 6 | 148
increased circulating triglyce... 6 | 24
increased sacral vertebrae num... 6 | 62
increased startle reflex 6 | 38
increased vertical activity 6 | 18
oligodactyly 6 | 14
straub tail 6 | 26
decreased T cell number 5 | 31
decreased circulating calcium ... 5 | 33
decreased vertical activity 5 | 22
enlarged spleen 5 | 26
increased body weight 5 | 42
increased circulating calcium ... 5 | 32
increased circulating iron lev... 5 | 25
increased circulating serum al... 5 | 25

Disease

psoriasis 1,476 | 6,685
ovarian cancer 1,302 | 8,484
osteosarcoma 1,182 | 7,933
glioblastoma 1,026 | 5,572
medulloblastoma, large-cell 1,015 | 6,234
lung cancer 870 | 4,466
lung carcinoma 808 | 2,844
pilocytic astrocytoma 753 | 3,086
atypical teratoid / rhabdoid tumor 731 | 4,369
Cancer 727 | 2,346
lung adenocarcinoma 701 | 2,713
interstitial cystitis 693 | 2,299
invasive ductal carcinoma 677 | 2,950
non-small cell lung cancer 670 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 667 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 656 | 3,289
Breast cancer 624 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 621 | 2,988
malignant mesothelioma 598 | 3,162
pancreatic cancer 584 | 2,300
ulcerative colitis 577 | 2,087
Carcinoma 554 | 2,147
pediatric high grade glioma 547 | 2,712
oligodendroglioma 507 | 2,849
cystic fibrosis 483 | 1,665
pituitary cancer 482 | 1,972
diabetes mellitus 474 | 1,663
primitive neuroectodermal tumor 455 | 3,031
subependymal giant cell astrocytoma 434 | 2,287
breast carcinoma 428 | 1,614
ductal carcinoma in situ 422 | 1,745
posterior fossa group A ependymoma 413 | 1,511
adult high grade glioma 400 | 2,148
ependymoma 382 | 2,514
tuberculosis 358 | 1,557
primary pancreatic ductal adenocarcinoma 356 | 1,271
group 4 medulloblastoma 343 | 1,875
astrocytic glioma 340 | 2,241
colon cancer 331 | 1,475
cutaneous lupus erythematosus 329 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 324 | 1,795
adrenocortical carcinoma 312 | 1,427
group 3 medulloblastoma 311 | 2,254
sonic hedgehog group medulloblastoma 288 | 1,482
astrocytoma 287 | 1,493
Atopic dermatitis 285 | 944
Rheumatoid Arthritis 254 | 1,160
gastric carcinoma 250 | 832
Pick disease 246 | 1,893
posterior fossa group B ependymoma 246 | 1,530
juvenile dermatomyositis 236 | 1,189
active Crohn's disease 229 | 918
nasopharyngeal carcinoma 228 | 1,056
medulloblastoma 225 | 1,524
Duchenne muscular dystrophy 221 | 602
esophageal adenocarcinoma 205 | 737
Kidney disease 199 | 396
primary Sjogren syndrome 192 | 789
atypical teratoid/rhabdoid tumor 189 | 1,095
Multiple Sclerosis 187 | 498
fibroadenoma 182 | 557
Obesity 180 | 616
Hypersensitivity reaction type II disease 177 | 235
Arthritis 173 | 248
Asthma 169 | 349
autosomal dominant Emery-Dreifuss muscular dystrophy 162 | 499
acute quadriplegic myopathy 157 | 1,157
Alzheimer's disease 156 | 644
mucosa-associated lymphoid tissue lymphoma 155 | 480
Atherosclerosis 152 | 275
Multiple myeloma 144 | 1,327
non primary Sjogren syndrome sicca 142 | 840
Endometriosis 139 | 535
Down syndrome 137 | 548
dermatomyositis 134 | 933
non-small cell lung carcinoma 134 | 413
Hypertension 133 | 287
Prostatic Neoplasms 133 | 471
Schizophrenia 132 | 501
Coronary artery disease 129 | 240
spina bifida 127 | 1,064
Autistic Disorder 121 | 320
Liver disease 116 | 219
aldosterone-producing adenoma 114 | 664
Anemia 111 | 252
Mammary Neoplasms 110 | 410
IGA Glomerulonephritis 109 | 454
Ankylosing spondylitis 108 | 138
Cerebrovascular disease 106 | 231
periodontitis 106 | 269
Heart disease 104 | 279
active ulcerative colitis 103 | 477
head and neck cancer 103 | 270
head and neck cancer and chronic obstructive pulmonary disease 103 | 237
urothelial carcinoma 103 | 318
Vascular disease 99 | 281
nephrosclerosis 99 | 329
interstitial lung disease 98 | 291
sarcoidosis 98 | 358
pancreatic carcinoma 96 | 567

Tissue

Nervous System 3,226 | 18,561
Digestive Tract 3,225 | 18,473
Female tissues 3,225 | 18,647
Endocrine System 3,209 | 18,512
Urinary Tract 3,201 | 18,444
Liver and Pancreas 3,157 | 18,136
Skin and soft tissues 3,139 | 18,115
Blood and immune system 3,099 | 17,995
Cardiovascular System 3,094 | 17,958
Male tissues 3,087 | 17,969
Respiratory system 3,027 | 17,484

Target Family

Non-IDG 2,570 | 11,971
Enzyme 639 | 4,146
GPCR 92 | 406
Ion Channel 90 | 341
Kinase 79 | 634
Transporter 15 | 473
Transcription Factor 2 | 1,400

UniProt Keyword

Signal 3,487 | 3,487
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
T-cell receptor beta chain V region CTL-L17 TCRB Tdark Non-IDG 0.00000 0
T-cell receptor alpha chain V region HPB-MLT N/A Tdark Non-IDG 0.00000 0
T-cell receptor alpha chain V region CTL-L17 TCRA Tdark Non-IDG 0.00000 0
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
HLA class II histocompatibility antigen, DRB1-14 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 337
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628