Development Level

Tbio 14 | 11,445
Tchem 6 | 1,598
Tdark 5 | 6,588
Tclin 2 | 613

IMPC Phenotype

decreased cardiac muscle contr... 1 | 11
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
increased circulating HDL chol... 1 | 80
increased mean platelet volume 1 | 45
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 13 | 11,493
psoriasis 13 | 6,694
osteosarcoma 12 | 7,950
medulloblastoma, large-cell 11 | 6,241
ovarian cancer 10 | 8,520
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
ependymoma 8 | 4,679
lung cancer 8 | 4,740
adult high grade glioma 7 | 3,801
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung carcinoma 7 | 2,843
astrocytic glioma 6 | 2,597
glioblastoma 6 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
ulcerative colitis 6 | 1,819
Astrocytoma, Pilocytic 5 | 3,081
group 4 medulloblastoma 5 | 1,855
interstitial cystitis 5 | 2,312
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primitive neuroectodermal tumor 5 | 3,035
Breast cancer 4 | 3,578
Liver Cirrhosis, Experimental 4 | 769
Obesity 4 | 678
colon cancer 4 | 1,478
group 3 medulloblastoma 4 | 4,104
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
Adverse reaction to drug 3 | 61
Cocaine-Related Disorders 3 | 92
Drug-Related Side Effects and Adverse Reactions 3 | 62
Pick disease 3 | 1,894
breast carcinoma 3 | 1,638
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Alzheimer Disease 2 | 83
Alzheimer's disease 2 | 658
Amnestic disorder 2 | 35
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Carcinoma, Renal Cell 2 | 124
Dementia 2 | 175
Dementia associated with Parkinson's Disease 2 | 2
Echinococcosis 2 | 26
Mammary Neoplasms 2 | 425
Muscular Dystrophies 2 | 8
Muscular dystrophy 2 | 75
Myasthenia gravis 2 | 23
Myocardial Ischemia 2 | 169
Organophosphate poisoning 2 | 4
Parkinson's disease 2 | 392
Poisoning 2 | 16
Renal Cell Carcinoma 2 | 214
Schizophrenia 2 | 1,160
Seizures 2 | 596
Steatorrhea 2 | 34
Toxic encephalopathy 2 | 141
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
medulloblastoma 2 | 720
non-small cell lung carcinoma 2 | 317
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
Amyloidosis 1 | 67
Asperger syndrome 1 | 37
Barrett's esophagus 1 | 182
Brain Injuries 1 | 65
Brain disease 1 | 96
Chondrosarcoma 1 | 21
Cocaine abuse 1 | 19
Diabetes Mellitus, Experimental 1 | 108
Esotropia 1 | 31
Fatty liver disease 1 | 103
Growth Disorders 1 | 35
Human immunodeficiency virus infectious disease 1 | 138
Hyperactive behavior 1 | 91
Hyperkinesis 1 | 32
Hyperopia 1 | 70
Hypertriglyceridemia 1 | 17
Kabuki syndrome 1 | 27
Muscular fasciculation 1 | 22
Open-angle glaucoma 1 | 27
Pancreatitis 1 | 123
Paralysed 1 | 42
Paralysis 1 | 9
Pericarditis 1 | 13
Respiratory Distress Syndrome, Adult 1 | 40
Retinoblastoma 1 | 19
Rickets 1 | 49
Wilson disease 1 | 16
maturity-onset diabetes of the young 1 | 32

Tissue

Endocrine System 26 | 18,159
Liver and Pancreas 26 | 16,750
Nervous System 26 | 16,725
Skin and soft tissues 26 | 17,230
Digestive Tract 25 | 17,369
Male tissues 25 | 17,142
Urinary Tract 25 | 16,678
Blood and immune system 24 | 16,909
Female tissues 24 | 17,400
Respiratory system 24 | 16,393
Cardiovascular System 23 | 15,192

Target Family

Enzyme 27 | 4,145

UniProt Keyword

Serine esterase 27 | 27
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acyl-coenzyme A thioesterase 9, mitochondrial ACOT9 Tdark Enzyme -0.13093 1.45 171
Phospholipase ABHD3 ABHD3 Tbio Enzyme -0.41218 2.23 91
Acyl-coenzyme A thioesterase 1 ACOT1 Tdark Enzyme -2.14311 129.6 43
Acyl-coenzyme A thioesterase 4 ACOT4 Tbio Enzyme -0.53787 2.87 58
Protein ABHD1 ABHD1 Tdark Enzyme -0.22185 2.20 106
Cytosolic acyl coenzyme A thioester hydrolase ACOT7 Tbio Enzyme -2.06780 111.8 102
Monoacylglycerol lipase ABHD2 ABHD2 Tbio Enzyme -1.02814 11.4 112
Carboxylesterase 5A CES5A Tbio Enzyme -1.89695 99.6 99
Palmitoleoyl-protein carboxylesterase NOTUM NOTUM Tchem Enzyme -2.22791 161.6 137
Putative cytosolic acyl coenzyme A thioester hydrolase-like ACOT7L Tdark Enzyme 0.00000 0