Development Level

Tbio 16 | 11,445
Tdark 8 | 6,588
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal spine curvature 1 | 9
abnormal testis morphology 1 | 43
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
hydrometra 1 | 53
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
small testis 1 | 58
vertebral fusion 1 | 23

Disease

ovarian cancer 14 | 8,520
osteosarcoma 12 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Cancer 8 | 2,499
glioblastoma 8 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Carcinoma 7 | 11,493
Staphyloenterotoxemia 7 | 18
atypical teratoid / rhabdoid tumor 7 | 5,112
medulloblastoma, large-cell 7 | 6,241
Keshan disease 6 | 17
adult high grade glioma 6 | 3,801
group 3 medulloblastoma 6 | 4,104
lung adenocarcinoma 6 | 2,716
lung cancer 6 | 4,740
psoriasis 6 | 6,694
Hyperthyroidism 5 | 53
ependymoma 5 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
Breast Neoplasms 4 | 445
Hypothyroidism 4 | 122
Liver Cirrhosis, Experimental 4 | 769
Mammary Neoplasms 4 | 425
Multiple myeloma 4 | 1,332
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
invasive ductal carcinoma 4 | 2,951
oligodendroglioma 4 | 2,850
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Colorectal Neoplasms 3 | 243
Endometriosis 3 | 540
Epilepsy 3 | 792
Lung Neoplasms 3 | 232
Obesity 3 | 678
Osteoarthritis 3 | 184
Pick disease 3 | 1,894
Toxic shock syndrome 3 | 28
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
malignant mesothelioma 3 | 3,232
posterior fossa group A ependymoma 3 | 468
primitive neuroectodermal tumor 3 | 3,035
ulcerative colitis 3 | 1,819
Adenoma 2 | 167
Atopic dermatitis 2 | 952
Autism Spectrum Disorders 2 | 75
Autism spectrum disorder 2 | 101
Autosomal recessive predisposition 2 | 1,442
Cadmium poisoning 2 | 3
Cardiomyopathy, Dilated 2 | 83
Fatty Liver 2 | 70
Hyperthyroxinemia 2 | 9
Infertility, Male 2 | 46
Insulin Resistance 2 | 72
Liver neoplasms 2 | 130
Male infertility 2 | 206
Mastitis 2 | 48
Mesothelioma 2 | 38
Neoplasm Metastasis 2 | 168
Neurodegenerative Diseases 2 | 38
Neurodegenerative Disorders 2 | 79
Thyroid Diseases 2 | 24
Thyrotoxicosis 2 | 38
Vascular disease 2 | 319
active Crohn's disease 2 | 922
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
non primary Sjogren syndrome sicca 2 | 891
Acrocephaly 1 | 12
Adenocarcinoma 1 | 122
Atrioventricular block 1 | 35
Autoimmune thyroiditis 1 | 27
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Squamous Cell 1 | 110
Diabetes Mellitus, Experimental 1 | 108
Echinococcosis 1 | 26
Fibrosis 1 | 44
Flared iliac wings 1 | 13
Glucose Intolerance 1 | 19
Impaired glucose tolerance 1 | 28
Malignant hyperthermia 1 | 26
Muscular Dystrophies 1 | 8
Scoliosis 1 | 44
Short ribs 1 | 30
Thyroid cancer, papillary 1 | 14

Tissue

Endocrine System 24 | 18,159
Male tissues 24 | 17,142
Blood and immune system 23 | 16,909
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Nervous System 23 | 16,725
Digestive Tract 22 | 17,369
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Cardiovascular System 20 | 15,192

Target Family

Enzyme 15 | 4,145
Non-IDG 11 | 12,091

UniProt Keyword

Selenocysteine 26 | 26
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutathione peroxidase 1 GPX1 Tbio Enzyme -2.94289 886.7 350
Selenoprotein S SELENOS Tbio Non-IDG -2.96621 867.6 92
Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 Tbio Enzyme -2.88891 707.6 227
Glutathione peroxidase 3 GPX3 Tbio Enzyme -2.68271 472.3 196
Thioredoxin reductase 2, mitochondrial TXNRD2 Tbio Enzyme -2.65568 461.7 168
Type II iodothyronine deiodinase DIO2 Tbio Enzyme -2.60036 368.6 134
Selenoprotein P SELENOP Tbio Non-IDG -2.48868 339.5 110
Thioredoxin reductase 1, cytoplasmic TXNRD1 Tclin Enzyme -2.28524 208.2 308
Glutathione peroxidase 2 GPX2 Tbio Enzyme -2.29928 197.6 144
Type I iodothyronine deiodinase DIO1 Tclin Enzyme -2.19858 153.3 82