Development Level

Tbio 1,303 | 11,445
Tdark 511 | 6,588
Tchem 167 | 1,598
Tclin 60 | 613

Collection

RFA-RM-18-021 5 | 328
GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 44 | 979
preweaning lethality, incomple... 44 | 499
decreased vertical activity 38 | 208
enlarged heart 36 | 210
abnormal heart morphology 30 | 162
abnormal seminal vesicle morph... 23 | 114
decreased total body fat amoun... 20 | 207
abnormal behavior 17 | 298
decreased bone mineral content 17 | 151
embryonic lethality prior to t... 16 | 278
abnormal bone structure 15 | 187
hypoactivity 15 | 132
decreased circulating glucose ... 14 | 126
increased total body fat amoun... 14 | 134
short tibia 14 | 97
abnormal embryo size 12 | 220
abnormal kidney morphology 12 | 65
decreased lean body mass 12 | 135
small superior vagus ganglion 12 | 74
decreased lymphocyte cell numb... 11 | 83
improved glucose tolerance 11 | 79
increased lean body mass 11 | 172
abnormal eye morphology 10 | 68
cataract 10 | 92
decreased circulating choleste... 10 | 93
decreased circulating serum al... 10 | 82
decreased fasted circulating g... 10 | 65
hydrometra 10 | 53
increased bone mineral content 10 | 108
prolonged ST segment 10 | 36
decreased body length 9 | 101
decreased body weight 9 | 161
decreased bone mineral density 9 | 126
decreased grip strength 9 | 116
decreased mean corpuscular vol... 9 | 79
hyperactivity 9 | 148
impaired glucose tolerance 9 | 75
increased circulating alkaline... 9 | 122
increased fasted circulating g... 9 | 76
increased monocyte cell number 9 | 63
abnormal retina morphology 8 | 71
abnormal skin morphology 8 | 50
abnormal sleep behavior 8 | 70
abnormal testis morphology 8 | 43
decreased startle reflex 8 | 75
impaired righting response 8 | 26
increased circulating HDL chol... 8 | 80
increased or absent threshold ... 8 | 101
abnormal coat-hair pigmentatio... 7 | 64
abnormal gait 7 | 69
decreased circulating HDL chol... 7 | 68
decreased circulating insulin ... 7 | 76
decreased circulating triglyce... 7 | 79
decreased erythrocyte cell num... 7 | 62
decreased leukocyte cell numbe... 7 | 73
embryonic growth retardation 7 | 106
increased bone mineral density 7 | 72
increased circulating choleste... 7 | 66
increased heart weight 7 | 62
increased hematocrit 7 | 46
increased neutrophil cell numb... 7 | 46
limb grasping 7 | 41
small testis 7 | 58
abnormal cranium morphology 6 | 36
abnormal tail morphology 6 | 25
abnormal tooth morphology 6 | 24
decreased blood urea nitrogen ... 6 | 51
decreased mean corpuscular hem... 6 | 31
embryonic lethality prior to o... 6 | 239
increased blood urea nitrogen ... 6 | 48
increased circulating total pr... 6 | 28
increased lymphocyte cell numb... 6 | 32
increased mean corpuscular hem... 6 | 96
increased mean corpuscular vol... 6 | 92
increased startle reflex 6 | 112
persistence of hyaloid vascula... 6 | 33
prolonged QT interval 6 | 38
abnormal lens morphology 5 | 81
abnormal vibrissa morphology 5 | 25
decreased circulating creatini... 5 | 39
decreased circulating free fat... 5 | 31
decreased circulating total pr... 5 | 49
decreased hematocrit 5 | 46
decreased hemoglobin content 5 | 68
decreased neutrophil cell numb... 5 | 42
decreased prepulse inhibition 5 | 82
enlarged lymph nodes 5 | 37
increased leukocyte cell numbe... 5 | 47
increased mean platelet volume 5 | 45
male infertility 5 | 123
thrombocytopenia 5 | 56
abnormal epididymis morphology 4 | 42
abnormal locomotor behavior 4 | 24
abnormal neural tube morpholog... 4 | 12
abnormal retinal vasculature m... 4 | 27
decreased circulating alanine ... 4 | 47
decreased eosinophil cell numb... 4 | 24
impaired pupillary reflex 4 | 26
increased circulating triglyce... 4 | 42
prenatal lethality prior to he... 4 | 87

Disease

Carcinoma 948 | 11,493
psoriasis 835 | 6,694
ovarian cancer 705 | 8,520
osteosarcoma 591 | 7,950
lung cancer 549 | 4,740
glioblastoma 533 | 5,792
medulloblastoma, large-cell 503 | 6,241
Cancer 458 | 2,499
Breast cancer 437 | 3,578
lung carcinoma 429 | 2,843
ependymoma 422 | 4,679
lung adenocarcinoma 417 | 2,716
non-small cell lung cancer 405 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 404 | 2,955
atypical teratoid / rhabdoid tumor 399 | 5,112
invasive ductal carcinoma 397 | 2,951
interstitial cystitis 396 | 2,312
pancreatic cancer 394 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 392 | 3,291
Astrocytoma, Pilocytic 388 | 3,081
malignant mesothelioma 377 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 374 | 2,989
adult high grade glioma 373 | 3,801
cystic fibrosis 337 | 1,696
ulcerative colitis 317 | 1,819
pituitary cancer 294 | 1,972
diabetes mellitus 293 | 1,728
group 3 medulloblastoma 293 | 4,104
breast carcinoma 266 | 1,638
oligodendroglioma 257 | 2,850
ductal carcinoma in situ 252 | 1,745
tuberculosis 238 | 2,010
Kidney cancer 237 | 2,613
pancreatic ductal adenocarcinoma liver metastasis 226 | 1,962
colon cancer 216 | 1,478
Autosomal recessive predisposition 215 | 1,442
astrocytic glioma 209 | 2,597
primitive neuroectodermal tumor 209 | 3,035
Atopic dermatitis 204 | 952
subependymal giant cell astrocytoma 202 | 2,287
adrenocortical carcinoma 192 | 1,428
cutaneous lupus erythematosus 188 | 1,057
primary pancreatic ductal adenocarcinoma 187 | 1,109
Schizophrenia 170 | 1,160
Kidney disease 155 | 430
gastric carcinoma 153 | 807
nasopharyngeal carcinoma 153 | 1,058
Liver Cirrhosis, Experimental 152 | 769
group 4 medulloblastoma 151 | 1,855
Obesity 146 | 678
Duchenne muscular dystrophy 142 | 601
Melanoma 134 | 711
Rheumatoid arthritis 134 | 1,191
Hypertension 133 | 396
juvenile dermatomyositis 133 | 1,187
Atherosclerosis 130 | 291
active Crohn's disease 126 | 922
fibroadenoma 123 | 559
esophageal adenocarcinoma 121 | 737
Pick disease 119 | 1,894
Asthma 118 | 385
active ulcerative colitis 114 | 764
Coronary artery disease 112 | 268
autosomal dominant Emery-Dreifuss muscular dystrophy 109 | 510
Arthritis 105 | 290
Endometriosis 104 | 540
Multiple Sclerosis 102 | 540
Bipolar Disorder 99 | 666
Prostatic Neoplasms 97 | 495
Skin cancer 97 | 469
astrocytoma 96 | 1,146
pediatric high grade glioma 95 | 1,064
mucosa-associated lymphoid tissue lymphoma 94 | 484
acute quadriplegic myopathy 91 | 1,158
Alzheimer's disease 89 | 658
periodontitis 88 | 293
Hypertensive disease 87 | 292
Osteoporosis 87 | 363
Breast Neoplasms 86 | 445
Mammary Neoplasms 85 | 425
primary Sjogren syndrome 85 | 735
Heart disease 84 | 306
non primary Sjogren syndrome sicca 84 | 891
spina bifida 84 | 1,074
Cerebrovascular disease 83 | 238
Vascular disease 83 | 319
Lung disease 82 | 142
Depressive disorder 80 | 409
limb girdle muscular dystrophy 2A 80 | 213
Hypersensitivity reaction type II disease 79 | 253
Liver cancer 78 | 604
Liver disease 75 | 237
interstitial lung disease 75 | 298
posterior fossa group A ependymoma 73 | 468
Anemia 72 | 365
chronic rhinosinusitis 69 | 512
dermatomyositis 69 | 966
Polycystic ovary syndrome 68 | 360
Spontaneous abortion 68 | 113
urothelial carcinoma 68 | 318

Tissue

Endocrine System 1,703 | 18,159
Digestive Tract 1,655 | 17,369
Female tissues 1,649 | 17,400
Skin and soft tissues 1,614 | 17,230
Male tissues 1,610 | 17,142
Blood and immune system 1,576 | 16,909
Liver and Pancreas 1,547 | 16,750
Urinary Tract 1,525 | 16,678
Nervous System 1,467 | 16,725
Respiratory system 1,460 | 16,393
Cardiovascular System 1,249 | 15,192

Target Family

Non-IDG 1,619 | 12,091
Enzyme 383 | 4,145
Kinase 18 | 634
Transcription Factor 9 | 1,400
GPCR 7 | 408
Ion Channel 5 | 344

UniProt Keyword

Secreted 2,041 | 2,041
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zona pellucida-binding protein 1 ZPBP Tdark Non-IDG -1.44041 27.1 43
Redox-regulatory protein FAM213A FAM213A Tbio Non-IDG -1.51277 30.6 63
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
Pro-neuregulin-4, membrane-bound isoform NRG4 Tbio Non-IDG -1.33564 24.6 137
Epididymal-specific lipocalin-9 LCN9 Tdark Non-IDG -0.47470 3.06 61
Opiorphin prepropeptide OPRPN Tdark Non-IDG -1.76019 58.0 15
Hypoxia-inducible lipid droplet-associated protein HILPDA Tbio Non-IDG -1.24205 21.6 18
Sperm acrosome-associated protein 5 SPACA5B Tdark Enzyme 0.14 0.79 56
Immunoglobulin heavy variable 7-4-1 IGHV7-4-1 Tdark Non-IDG 0.00000 0