Development Level

Tbio 1,157 | 10,625
Tdark 484 | 7,003
Tchem 242 | 1,890
Tclin 58 | 602

Collection

Eligible Ion Channel Proteins 3 | 117
Eligible non-olfactory GPCR Proteins 3 | 143

IMPC Term

preweaning lethality, complete... 38 | 633
enlarged heart 25 | 111
decreased total body fat amoun... 18 | 186
preweaning lethality, incomple... 17 | 260
decreased bone mineral content 15 | 157
decreased lean body mass 15 | 195
abnormal heart morphology 14 | 51
short tibia 13 | 82
decreased circulating glucose ... 12 | 121
increased or absent threshold ... 12 | 128
abnormal bone structure 11 | 131
abnormal seminal vesicle morph... 11 | 47
decreased bone mineral density 11 | 126
decreased circulating serum al... 11 | 79
decreased body weight 10 | 174
hypoactivity 10 | 89
abnormal behavior 9 | 226
abnormal embryo size 9 | 112
abnormal lens morphology 9 | 73
decreased circulating insulin ... 9 | 75
decreased grip strength 9 | 123
impaired glucose tolerance 9 | 52
abnormal kidney morphology 8 | 30
abnormal retina morphology 8 | 100
decreased heart weight 8 | 44
embryonic lethality prior to t... 8 | 187
improved glucose tolerance 8 | 56
increased circulating HDL chol... 8 | 63
increased circulating alkaline... 8 | 119
increased fasted circulating g... 8 | 68
increased mean corpuscular vol... 8 | 91
abnormal coat/hair pigmentatio... 7 | 54
decreased circulating triglyce... 7 | 83
increased lean body mass 7 | 107
abnormal cranium morphology 6 | 32
decreased body length 6 | 108
decreased circulating HDL chol... 6 | 77
decreased circulating choleste... 6 | 85
impaired righting response 6 | 19
increased exploration in new e... 6 | 56
increased grip strength 6 | 83
increased hemoglobin content 6 | 45
increased mean corpuscular hem... 6 | 93
increased total body fat amoun... 6 | 57
abnormal retinal pigmentation 5 | 61
abnormal sleep behavior 5 | 63
abnormal tail morphology 5 | 17
abnormal tooth morphology 5 | 24
cataract 5 | 26
decreased circulating alanine ... 5 | 53
decreased circulating free fat... 5 | 39
decreased erythrocyte cell num... 5 | 43
decreased fasted circulating g... 5 | 49
decreased hemoglobin content 5 | 53
decreased mean corpuscular vol... 5 | 50
decreased monocyte cell number 5 | 28
enlarged epididymis 5 | 27
hyperactivity 5 | 108
increased bone mineral content 5 | 92
increased hematocrit 5 | 36
increased startle reflex 5 | 38
small testis 5 | 37
thrombocytopenia 5 | 46
abnormal behavioral response t... 4 | 52
abnormal bone mineralization 4 | 55
abnormal eye morphology 4 | 38
abnormal gait 4 | 51
abnormal skin morphology 4 | 23
abnormal spleen morphology 4 | 36
abnormal testis morphology 4 | 30
abnormal tibia morphology 4 | 14
decreased circulating iron lev... 4 | 25
decreased circulating total pr... 4 | 41
decreased leukocyte cell numbe... 4 | 54
decreased lumbar vertebrae num... 4 | 62
decreased mean corpuscular hem... 4 | 19
decreased prepulse inhibition 4 | 52
decreased rib number 4 | 59
decreased threshold for audito... 4 | 32
increased NK T cell number 4 | 11
increased blood urea nitrogen ... 4 | 44
increased circulating choleste... 4 | 53
increased sacral vertebrae num... 4 | 62
limb grasping 4 | 35
abnormal coat appearance 3 | 25
abnormal epididymis morphology 3 | 31
abnormal neural tube morpholog... 3 | 8
abnormal vibrissa morphology 3 | 17
abnormal vocalization 3 | 21
decreased caudal vertebrae num... 3 | 49
embryonic lethality prior to o... 3 | 148
female infertility 3 | 34
increased circulating aspartat... 3 | 17
increased circulating potassiu... 3 | 31
increased circulating serum al... 3 | 25
increased circulating sodium l... 3 | 71
increased circulating total pr... 3 | 20
increased heart weight 3 | 37
persistence of hyaloid vascula... 3 | 22
straub tail 3 | 26

Disease

psoriasis 824 | 6,685
ovarian cancer 699 | 8,484
osteosarcoma 576 | 7,933
lung cancer 514 | 4,466
medulloblastoma, large-cell 501 | 6,234
glioblastoma 498 | 5,572
Cancer 431 | 2,346
lung carcinoma 427 | 2,844
lung adenocarcinoma 413 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 406 | 2,956
invasive ductal carcinoma 395 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 391 | 3,289
interstitial cystitis 389 | 2,299
pilocytic astrocytoma 387 | 3,086
non-small cell lung cancer 382 | 2,798
pancreatic cancer 378 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 375 | 2,988
Breast cancer 357 | 3,094
ulcerative colitis 351 | 2,087
malignant mesothelioma 341 | 3,162
atypical teratoid / rhabdoid tumor 337 | 4,369
cystic fibrosis 330 | 1,665
pituitary cancer 291 | 1,972
diabetes mellitus 281 | 1,663
breast carcinoma 264 | 1,614
oligodendroglioma 256 | 2,849
ductal carcinoma in situ 253 | 1,745
pediatric high grade glioma 249 | 2,712
posterior fossa group A ependymoma 239 | 1,511
primary pancreatic ductal adenocarcinoma 219 | 1,271
adult high grade glioma 214 | 2,148
Carcinoma 213 | 2,147
colon cancer 211 | 1,475
primitive neuroectodermal tumor 207 | 3,031
tuberculosis 204 | 1,557
Atopic dermatitis 203 | 944
subependymal giant cell astrocytoma 197 | 2,287
adrenocortical carcinoma 190 | 1,427
pancreatic ductal adenocarcinoma liver metastasis 190 | 1,795
cutaneous lupus erythematosus 185 | 1,056
sonic hedgehog group medulloblastoma 171 | 1,482
astrocytic glioma 169 | 2,241
ependymoma 165 | 2,514
gastric carcinoma 159 | 832
group 3 medulloblastoma 157 | 2,254
group 4 medulloblastoma 156 | 1,875
nasopharyngeal carcinoma 154 | 1,056
Duchenne muscular dystrophy 142 | 602
Kidney disease 140 | 396
astrocytoma 134 | 1,493
Obesity 130 | 616
juvenile dermatomyositis 130 | 1,189
active Crohn's disease 126 | 918
Atherosclerosis 125 | 275
Rheumatoid Arthritis 124 | 1,160
fibroadenoma 124 | 557
esophageal adenocarcinoma 122 | 737
Pick disease 118 | 1,893
posterior fossa group B ependymoma 118 | 1,530
Asthma 116 | 349
autosomal dominant Emery-Dreifuss muscular dystrophy 106 | 499
Hypertension 104 | 287
Endometriosis 102 | 535
Coronary artery disease 101 | 240
primary Sjogren syndrome 97 | 789
Arthritis 95 | 248
Prostatic Neoplasms 94 | 471
Multiple Sclerosis 93 | 498
atypical teratoid/rhabdoid tumor 91 | 1,095
mucosa-associated lymphoid tissue lymphoma 91 | 480
acute quadriplegic myopathy 88 | 1,157
medulloblastoma 88 | 1,524
Alzheimer's disease 84 | 644
Mammary Neoplasms 84 | 410
non-small cell lung carcinoma 83 | 413
spina bifida 83 | 1,064
Heart disease 80 | 279
Cerebrovascular disease 78 | 231
periodontitis 78 | 269
Lung disease 77 | 132
Vascular disease 77 | 281
Hypersensitivity reaction type II disease 74 | 235
interstitial lung disease 73 | 291
non primary Sjogren syndrome sicca 73 | 840
Down syndrome 71 | 548
Osteoporosis 71 | 257
Liver disease 70 | 219
chronic rhinosinusitis 69 | 512
urothelial carcinoma 68 | 318
dermatomyositis 67 | 933
Spontaneous abortion 65 | 108
inflammatory breast cancer 64 | 404
limb girdle muscular dystrophy 2A 64 | 156
Becker muscular dystrophy 63 | 187
active ulcerative colitis 63 | 477
Hypertensive disease 62 | 193
Polycystic Ovary Syndrome 62 | 332
Schizophrenia 62 | 501
sarcoidosis 62 | 358
aldosterone-producing adenoma 61 | 664

Tissue

Nervous System 1,798 | 18,561
Female tissues 1,793 | 18,647
Digestive Tract 1,792 | 18,473
Endocrine System 1,784 | 18,512
Urinary Tract 1,771 | 18,444
Skin and soft tissues 1,744 | 18,115
Liver and Pancreas 1,735 | 18,136
Cardiovascular System 1,707 | 17,958
Blood and immune system 1,694 | 17,995
Male tissues 1,686 | 17,969
Respiratory system 1,646 | 17,484

Target Family

Non-IDG 1,523 | 11,971
Enzyme 380 | 4,146
Kinase 18 | 634
Transcription Factor 9 | 1,400
GPCR 6 | 406
Ion Channel 5 | 341

UniProt Keyword

Secreted 1,941 | 1,941
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -1.83671 93.1 157