Development Level

Tbio 53 | 11,651
Tchem 6 | 1,388
Tdark 4 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

impaired glucose tolerance 2 | 75
increased circulating HDL chol... 2 | 80
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal seminal vesicle morph... 1 | 114
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
corneal opacity 1 | 32
decreased caudal vertebrae num... 1 | 53
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased fasted circulating g... 1 | 65
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased startle reflex 1 | 75
enlarged spleen 1 | 41
hyperactivity 1 | 148
increased circulating LDL chol... 1 | 13
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
small kidney 1 | 16
small spleen 1 | 19
small testis 1 | 58

Disease

Carcinoma 45 | 11,493
medulloblastoma, large-cell 36 | 6,241
ovarian cancer 36 | 8,520
atypical teratoid / rhabdoid tumor 33 | 5,112
ependymoma 32 | 4,679
glioblastoma 31 | 5,792
lung cancer 29 | 4,740
osteosarcoma 29 | 7,950
group 3 medulloblastoma 27 | 4,104
primitive neuroectodermal tumor 25 | 3,035
adult high grade glioma 23 | 3,801
psoriasis 22 | 6,694
Astrocytoma, Pilocytic 21 | 3,081
Breast cancer 21 | 3,578
lung adenocarcinoma 20 | 2,716
non-small cell lung cancer 20 | 2,890
invasive ductal carcinoma 19 | 2,951
oligodendroglioma 19 | 2,850
Cancer 18 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
malignant mesothelioma 18 | 3,232
subependymal giant cell astrocytoma 18 | 2,287
interstitial cystitis 17 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
astrocytic glioma 15 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
Pick disease 13 | 1,894
breast carcinoma 13 | 1,638
group 4 medulloblastoma 13 | 1,855
lung carcinoma 13 | 2,843
pancreatic cancer 13 | 2,398
ductal carcinoma in situ 11 | 1,745
pituitary cancer 11 | 1,972
ulcerative colitis 11 | 1,819
Kidney cancer 10 | 2,613
Schizophrenia 10 | 1,160
colon cancer 9 | 1,478
astrocytoma 8 | 1,146
cystic fibrosis 8 | 1,696
diabetes mellitus 8 | 1,728
tuberculosis 8 | 2,010
Intellectual disability 7 | 1,016
active Crohn's disease 7 | 922
acute quadriplegic myopathy 7 | 1,158
dermatomyositis 7 | 966
gastric carcinoma 7 | 807
juvenile dermatomyositis 7 | 1,187
Down syndrome 6 | 499
Multiple myeloma 6 | 1,332
cutaneous lupus erythematosus 6 | 1,057
pediatric high grade glioma 6 | 1,064
Acquired metabolic disease 5 | 336
Atopic dermatitis 5 | 952
Autosomal recessive predisposition 5 | 1,442
Duchenne muscular dystrophy 5 | 601
Liver Cirrhosis, Experimental 5 | 769
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alzheimer's disease 4 | 658
Autistic Disorder 4 | 364
Dull intelligence 4 | 645
Epilepsy 4 | 792
Kidney disease 4 | 430
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Oculocerebrorenal syndrome 4 | 29
Poor school performance 4 | 645
Rheumatoid arthritis 4 | 1,191
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 783
Autism spectrum disorder 3 | 101
Breast Neoplasms 3 | 445
Cognitive delay 3 | 608
Endometriosis 3 | 540
Global developmental delay 3 | 608
Heart disease 3 | 306
Hypertensive disease 3 | 292
Mental and motor retardation 3 | 608
Multiple Sclerosis 3 | 540
Muscle hypotonia 3 | 571
Proteinuria 3 | 144
Short nose 3 | 132
Small head 3 | 374
Small nose 3 | 132
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
atypical teratoid/rhabdoid tumor 3 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
esophageal adenocarcinoma 3 | 737
interstitial lung disease 3 | 298
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung carcinoma 3 | 317
pancreatic carcinoma 3 | 562
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074
tuberculosis and treatment for 6 months 3 | 409
aldosterone-producing adenoma 2 | 665
mucosa-associated lymphoid tissue lymphoma 2 | 484

Tissue

Digestive Tract 61 | 17,369
Endocrine System 61 | 18,159
Female tissues 61 | 17,400
Liver and Pancreas 61 | 16,750
Male tissues 61 | 17,142
Nervous System 61 | 16,725
Respiratory system 61 | 16,393
Skin and soft tissues 61 | 17,230
Blood and immune system 60 | 16,909
Urinary Tract 60 | 16,678
Cardiovascular System 59 | 15,192

Target Family

Non-IDG 39 | 12,091
Enzyme 22 | 4,145
Kinase 2 | 634

UniProt Keyword

SH3-binding 63 | 63
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A INPP5J Tbio Enzyme -1.87182 73.3 126
E3 ubiquitin-protein ligase DTX1 DTX1 Tbio Enzyme -2.07595 115.2 134
Securin PTTG1 Tbio Non-IDG -2.42127 261.4 311
Integrin beta-1-binding protein 2 ITGB1BP2 Tbio Non-IDG -1.09897 15.9 165
Protein quaking QKI Tbio Non-IDG -1.88311 75.1 278
NCK-interacting protein with SH3 domain NCKIPSD Tbio Non-IDG -1.01986 16.6 99
E3 ubiquitin-protein ligase CBL-C CBLC Tbio Enzyme -0.55931 2.63 246
SH3 and multiple ankyrin repeat domains protein 3 SHANK3 Tbio Non-IDG -2.26648 182.9 0
Alpha-(1,6)-fucosyltransferase FUT8 Tbio Enzyme -1.93724 92.9 145
Rho GTPase-activating protein 17 ARHGAP17 Tbio Enzyme -1.81816 63.6 121