Development Level

Tbio 50 | 10,625
Tchem 8 | 1,890
Tdark 5 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased mature B cell number 2 | 25
increased fasted circulating g... 2 | 68
abnormal QRS complex 1 | 25
abnormal behavior 1 | 226
abnormal coat appearance 1 | 25
abnormal posture 1 | 5
abnormal vibrissa morphology 1 | 17
corneal opacity 1 | 25
decreased CD4-positive, CD25-p... 1 | 24
decreased NK T cell number 1 | 28
decreased blood urea nitrogen ... 1 | 31
decreased circulating bilirubi... 1 | 14
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased fasted circulating g... 1 | 49
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
enlarged spleen 1 | 26
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
increased body weight 1 | 42
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating iron lev... 1 | 25
increased effector memory CD4-... 1 | 15
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased transitional stage T... 1 | 1
short tibia 1 | 82

Disease

medulloblastoma, large-cell 36 | 6,234
ovarian cancer 36 | 8,484
glioblastoma 30 | 5,572
osteosarcoma 29 | 7,933
atypical teratoid / rhabdoid tumor 27 | 4,369
lung cancer 27 | 4,466
primitive neuroectodermal tumor 25 | 3,031
psoriasis 23 | 6,685
pilocytic astrocytoma 21 | 3,086
lung adenocarcinoma 20 | 2,713
invasive ductal carcinoma 19 | 2,950
non-small cell lung cancer 19 | 2,798
oligodendroglioma 19 | 2,849
Breast cancer 18 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
malignant mesothelioma 18 | 3,162
pediatric high grade glioma 18 | 2,712
subependymal giant cell astrocytoma 18 | 2,287
interstitial cystitis 17 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
Cancer 15 | 2,346
ependymoma 15 | 2,514
group 3 medulloblastoma 14 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
Pick disease 13 | 1,893
breast carcinoma 13 | 1,614
group 4 medulloblastoma 13 | 1,875
lung carcinoma 13 | 2,844
pancreatic cancer 13 | 2,300
ulcerative colitis 13 | 2,087
astrocytic glioma 12 | 2,241
posterior fossa group A ependymoma 12 | 1,511
adult high grade glioma 11 | 2,148
astrocytoma 11 | 1,493
ductal carcinoma in situ 11 | 1,745
pituitary cancer 11 | 1,972
Carcinoma 10 | 2,147
atypical teratoid/rhabdoid tumor 9 | 1,095
colon cancer 9 | 1,475
cystic fibrosis 8 | 1,665
medulloblastoma 8 | 1,524
active Crohn's disease 7 | 918
acute quadriplegic myopathy 7 | 1,157
dermatomyositis 7 | 933
diabetes mellitus 7 | 1,663
gastric carcinoma 7 | 832
juvenile dermatomyositis 7 | 1,189
primary pancreatic ductal adenocarcinoma 7 | 1,271
sonic hedgehog group medulloblastoma 7 | 1,482
Down syndrome 6 | 548
Multiple myeloma 6 | 1,327
cutaneous lupus erythematosus 6 | 1,056
posterior fossa group B ependymoma 6 | 1,530
primary Sjogren syndrome 6 | 789
tuberculosis 6 | 1,557
Alzheimer's disease 5 | 644
Atopic dermatitis 5 | 944
Duchenne muscular dystrophy 5 | 602
Intellectual disability 5 | 573
tuberculosis and treatment for 6 months 5 | 686
Autistic Disorder 4 | 320
IGA Glomerulonephritis 4 | 454
Kidney disease 4 | 396
Rheumatoid Arthritis 4 | 1,160
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 780
non-small cell lung carcinoma 4 | 413
Acquired metabolic disease 3 | 267
Endometriosis 3 | 535
Heart disease 3 | 279
Oculocerebrorenal syndrome 3 | 23
Schizophrenia 3 | 501
adrenocortical carcinoma 3 | 1,427
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
esophageal adenocarcinoma 3 | 737
inflammatory breast cancer 3 | 404
interstitial lung disease 3 | 291
nasopharyngeal carcinoma 3 | 1,056
pancreatic carcinoma 3 | 567
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
progressive supranuclear palsy 3 | 674
spina bifida 3 | 1,064
Adenoma 2 | 165
Allergic rhinitis 2 | 91
Cognitive disorder 2 | 44
Coronary artery disease 2 | 240
Epilepsy 2 | 346
Multiple Sclerosis 2 | 498
Neurodegenerative disease 2 | 383
Parkinson's disease 2 | 364
Prostatic Neoplasms 2 | 471
aldosterone-producing adenoma 2 | 664
chronic rhinosinusitis 2 | 512
fibroadenoma 2 | 557
gastric cancer 2 | 430
glioblastoma multiforme 2 | 347
hereditary spastic paraplegia 2 | 313
mucosa-associated lymphoid tissue lymphoma 2 | 480
non diabetic and post-ischemic heart failure 2 | 200
systemic lupus erythematosus 2 | 156

Tissue

Blood and immune system 62 | 17,995
Cardiovascular System 62 | 17,958
Digestive Tract 62 | 18,473
Female tissues 62 | 18,647
Liver and Pancreas 62 | 18,136
Male tissues 62 | 17,969
Nervous System 62 | 18,561
Urinary Tract 62 | 18,444
Endocrine System 61 | 18,512
Respiratory system 61 | 17,484
Skin and soft tissues 60 | 18,115

Target Family

Non-IDG 39 | 11,971
Enzyme 22 | 4,146
Kinase 2 | 634

UniProt Keyword

SH3-binding 63 | 63
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Disintegrin and metalloproteinase domain-containing protein 19 ADAM19 Tbio Enzyme -1.55795 41.8 160
Dedicator of cytokinesis protein 3 DOCK3 Tbio Non-IDG -1.43918 28.2 44
Putative tyrosine-protein phosphatase auxilin DNAJC6 Tbio Enzyme -1.67985 56.6 79
Phospholipid scramblase 1 PLSCR1 Tbio Enzyme -1.74779 70.3 168
Vasodilator-stimulated phosphoprotein VASP Tbio Non-IDG -2.92544 883.0 726
E3 ubiquitin-protein ligase DTX1 DTX1 Tbio Enzyme -2.01291 106.0 127
Securin PTTG1 Tbio Non-IDG -2.36848 244.3 267
Ubiquitin carboxyl-terminal hydrolase 8 USP8 Tchem Enzyme -1.64199 52.9 189
SH3 and multiple ankyrin repeat domains protein 2 SHANK2 Tbio Non-IDG -1.75112 63.7 211
Low-density lipoprotein receptor-related protein 2 LRP2 Tbio Non-IDG -2.64998 484.3 141