Development Level

Tbio 89 | 10,625
Tdark 54 | 7,003
Tchem 28 | 1,890
Tclin 3 | 602

IMPC Term

abnormal behavior 8 | 226
decreased total body fat amoun... 7 | 186
preweaning lethality, complete... 7 | 633
increased grip strength 6 | 83
decreased lean body mass 5 | 195
increased sacral vertebrae num... 5 | 62
preweaning lethality, incomple... 5 | 260
abnormal retina morphology 4 | 100
decreased circulating HDL chol... 4 | 77
decreased circulating serum al... 4 | 79
increased lean body mass 4 | 107
abnormal bone structure 3 | 131
abnormal retinal pigmentation 3 | 61
decreased body length 3 | 108
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
decreased circulating choleste... 3 | 85
hyperactivity 3 | 108
increased total body fat amoun... 3 | 57
male infertility 3 | 62
short tibia 3 | 82
abnormal embryo size 2 | 112
abnormal gait 2 | 51
abnormal lens morphology 2 | 73
abnormal rib morphology 2 | 28
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating fructosa... 2 | 31
decreased circulating glucose ... 2 | 121
decreased eosinophil cell numb... 2 | 41
decreased grip strength 2 | 123
decreased hemoglobin content 2 | 53
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
decreased rib number 2 | 59
embryonic lethality prior to t... 2 | 187
female infertility 2 | 34
hypoactivity 2 | 89
increased bone mineral content 2 | 92
increased circulating HDL chol... 2 | 63
increased circulating creatini... 2 | 29
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 24
increased mean platelet volume 2 | 19
increased or absent threshold ... 2 | 128
increased red blood cell distr... 2 | 21
thrombocytopenia 2 | 46
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal heart left ventricle ... 1 | 20
abnormal joint morphology 1 | 14
abnormal pancreas morphology 1 | 6
abnormal snout morphology 1 | 18
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 14
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
corneal opacity 1 | 25
decreased B cell number 1 | 30
decreased CD4-positive, CD25-p... 1 | 24
decreased circulating chloride... 1 | 32
decreased circulating glycerol... 1 | 19
decreased circulating phosphat... 1 | 15
decreased effector memory CD8-... 1 | 24
decreased lumbar vertebrae num... 1 | 62
decreased pulmonary respirator... 1 | 4
decreased threshold for audito... 1 | 32
decreased total retina thickne... 1 | 20
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
hydrometra 1 | 13
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased cardiac muscle contr... 1 | 5
increased circulating LDL chol... 1 | 15
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating glycerol... 1 | 11
increased circulating potassiu... 1 | 31
increased mean corpuscular hem... 1 | 93
increased prepulse inhibition 1 | 21
polydactyly 1 | 22
premature death 1 | 5
small adrenal glands 1 | 15
small superior vagus ganglion 1 | 20
small testis 1 | 37
small thymus 1 | 11
straub tail 1 | 26
tremors 1 | 34

Disease

osteosarcoma 82 | 7,933
ovarian cancer 81 | 8,484
medulloblastoma, large-cell 47 | 6,234
psoriasis 43 | 6,685
glioblastoma 40 | 5,572
malignant mesothelioma 38 | 3,162
atypical teratoid / rhabdoid tumor 35 | 4,369
group 3 medulloblastoma 32 | 2,254
Cancer 31 | 2,346
lung cancer 31 | 4,466
primitive neuroectodermal tumor 31 | 3,031
Breast cancer 25 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
ependymoma 21 | 2,514
invasive ductal carcinoma 21 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,988
adult high grade glioma 19 | 2,148
pilocytic astrocytoma 19 | 3,086
Carcinoma 18 | 2,147
non-small cell lung cancer 18 | 2,798
oligodendroglioma 18 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,795
Pick disease 17 | 1,893
pediatric high grade glioma 16 | 2,712
Intellectual disability 15 | 573
astrocytic glioma 15 | 2,241
spina bifida 15 | 1,064
lung adenocarcinoma 14 | 2,713
juvenile dermatomyositis 13 | 1,189
pancreatic cancer 13 | 2,300
group 4 medulloblastoma 12 | 1,875
medulloblastoma 12 | 1,524
posterior fossa group B ependymoma 12 | 1,530
subependymal giant cell astrocytoma 12 | 2,287
dermatomyositis 11 | 933
lung carcinoma 11 | 2,844
Mammary Neoplasms 10 | 410
Multiple myeloma 10 | 1,327
acute quadriplegic myopathy 10 | 1,157
hepatocellular carcinoma 10 | 532
Rheumatoid Arthritis 9 | 1,160
ductal carcinoma in situ 9 | 1,745
pituitary cancer 9 | 1,972
sonic hedgehog group medulloblastoma 9 | 1,482
tuberculosis and treatment for 6 months 9 | 686
acute myeloid leukemia 8 | 780
adrenocortical carcinoma 8 | 1,427
atypical teratoid/rhabdoid tumor 8 | 1,095
gastric cancer 8 | 430
progressive supranuclear palsy 8 | 674
Waldenstrons macroglobulinemia 7 | 765
cystic fibrosis 7 | 1,665
diabetes mellitus 7 | 1,663
interstitial cystitis 7 | 2,299
non primary Sjogren syndrome sicca 7 | 840
posterior fossa group A ependymoma 7 | 1,511
tuberculosis 7 | 1,557
Schizophrenia 6 | 501
astrocytoma 6 | 1,493
breast carcinoma 6 | 1,614
Down syndrome 5 | 548
IGA Glomerulonephritis 5 | 454
Leukemia, Myelocytic, Acute 5 | 113
Liver carcinoma 5 | 217
Male infertility 5 | 170
Prostatic Neoplasms 5 | 471
nasopharyngeal carcinoma 5 | 1,056
primary Sjogren syndrome 5 | 789
primary pancreatic ductal adenocarcinoma 5 | 1,271
ulcerative colitis 5 | 2,087
Acquired metabolic disease 4 | 267
Adenoid Cystic Carcinoma 4 | 99
Alzheimer's disease 4 | 644
Amyotrophic Lateral Sclerosis 4 | 431
Autistic Disorder 4 | 320
Bladder Neoplasm 4 | 109
Crohn's disease 4 | 304
Microcephaly 4 | 149
Precursor Cell Lymphoblastic Leukemia Lymphoma 4 | 42
Stomach Neoplasms 4 | 282
active Crohn's disease 4 | 918
colon cancer 4 | 1,475
cutaneous lupus erythematosus 4 | 1,056
Amphetamine-Related Disorders 3 | 74
Becker muscular dystrophy 3 | 187
Duchenne muscular dystrophy 3 | 602
Hyperhomocysteinemia 3 | 34
Leukemia 3 | 88
Lymphoma, Follicular 3 | 20
Multiple Sclerosis 3 | 498
Muscle Weakness 3 | 92
Neuropathy 3 | 210
Peripheral Neuropathy 3 | 303
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
gastric carcinoma 3 | 832
head and neck cancer 3 | 270
inflammatory breast cancer 3 | 404
pancreatic carcinoma 3 | 567

Tissue

Endocrine System 168 | 18,512
Female tissues 168 | 18,647
Nervous System 168 | 18,561
Urinary Tract 168 | 18,444
Cardiovascular System 167 | 17,958
Digestive Tract 167 | 18,473
Blood and immune system 166 | 17,995
Liver and Pancreas 166 | 18,136
Skin and soft tissues 166 | 18,115
Male tissues 163 | 17,969
Respiratory system 163 | 17,484

Target Family

Enzyme 103 | 4,146
Epigenetic 44 | 242
TF/Epigenetic 15 | 38
Non-IDG 11 | 11,971
Transporter 1 | 473

UniProt Keyword

S-adenosyl-L-methionine 174 | 174
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-lysine N-methyltransferase SETD1B SETD1B Tbio Epigenetic -1.20916 14.6 78
Putative methyltransferase NSUN7 NSUN7 Tdark Enzyme -0.64137 4.34 10
SET domain-containing protein 9 SETD9 Tdark Non-IDG 0.21 0.40 71
Transmembrane O-methyltransferase LRTOMT Tbio Enzyme 13.4 29
Histone-lysine N-methyltransferase SETD1A SETD1A Tbio Epigenetic -2.53375 346.3 108
rRNA 2'-O-methyltransferase fibrillarin FBL Tbio Enzyme -3.17750 1580.2 240
Protein-L-isoaspartate(D-aspartate) O-methyltransferase PCMT1 Tbio Enzyme -1.78815 65.1 138
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase NOP2 Tbio Enzyme -1.48238 28.2 66
Histone-lysine N-methyltransferase 2E KMT2E Tbio Epigenetic -1.45323 38.7 150
Phenylethanolamine N-methyltransferase PNMT Tchem Enzyme -2.88545 840.4 235