Development Level

Tbio 17 | 11,445
Tchem 9 | 1,598
Tdark 9 | 6,588
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
absent pinna reflex 1 | 23
corneal opacity 1 | 32
decreased B cell number 1 | 5
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased mature B cell number 1 | 7
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased lean body mass 1 | 172
increased startle reflex 1 | 112
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 21 | 8,520
Carcinoma 12 | 11,493
Rheumatoid arthritis 11 | 1,191
osteosarcoma 11 | 7,950
atypical teratoid / rhabdoid tumor 10 | 5,112
ependymoma 10 | 4,679
glioblastoma 10 | 5,792
group 3 medulloblastoma 10 | 4,104
lung cancer 10 | 4,740
psoriasis 10 | 6,694
medulloblastoma, large-cell 8 | 6,241
Astrocytoma, Pilocytic 7 | 3,081
Pick disease 7 | 1,894
Prevention of Cardiac Transplant Rejection 7 | 15
Prevention of Kidney Transplant Rejection 7 | 17
Prevention of Liver Transplant Rejection 7 | 15
adult high grade glioma 7 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
Breast cancer 6 | 3,578
Cancer 6 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
Keratoconjunctivitis sicca 5 | 25
Severe Recalcitrant Psoriasis 5 | 12
Tear film insufficiency 5 | 15
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung adenocarcinoma 5 | 2,716
pituitary cancer 5 | 1,972
Atopic dermatitis 4 | 952
Bipolar Disorder 4 | 666
Stomach Neoplasms 4 | 300
group 4 medulloblastoma 4 | 1,855
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Intractable Eczema 3 | 5
Liver transplant rejection 3 | 5
Prevention of Transplant Rejection 3 | 6
Pulmonary lymphangioleiomyomatosis 3 | 5
Renal Cell Carcinoma 3 | 214
Renal transplant rejection 3 | 13
Transplanted organ rejection 3 | 10
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
dermatomyositis 3 | 966
gastric cancer 3 | 459
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
pancreatic carcinoma 3 | 562
post-traumatic stress disorder 3 | 40
primitive neuroectodermal tumor 3 | 3,035
Alzheimer's disease 2 | 658
Autosomal recessive predisposition 2 | 1,442
Becker muscular dystrophy 2 | 191
Bruck syndrome 2 | 10
Dentinogenesis imperfecta 2 | 25
Disease Progression 2 | 136
Duchenne muscular dystrophy 2 | 601
Major Depressive Disorder 2 | 301
Osteogenesis imperfecta 2 | 34
Osteogenesis imperfecta type III (disorder) 2 | 11
Osteogenesis imperfecta type IV (disorder) 2 | 10
Schizophrenia 2 | 1,160
Toxic encephalopathy 2 | 141
Unipolar Depression 2 | 250
Vascular disease 2 | 319
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
hepatocellular carcinoma 2 | 547
lung carcinoma 2 | 2,843
osteogenesis imperfecta type 3 2 | 11
osteogenesis imperfecta type 4 2 | 10
posterior fossa group B ependymoma 2 | 416
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
tuberculosis and treatment for 6 months 2 | 409
Acquired immunodeficiency syndrome 1 | 197
Barrett's esophagus 1 | 182
Blue sclera 1 | 32
Brachydactyly 1 | 156
Carcinoma, Non-Small-Cell Lung 1 | 107
Ehlers-Danlos syndrome 1 | 43
Generalized osteopenia 1 | 99
Osteopenia 1 | 99
Short limb dwarfism, disproportionate 1 | 22
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 35 | 16,909
Digestive Tract 35 | 17,369
Endocrine System 35 | 18,159
Skin and soft tissues 35 | 17,230
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Nervous System 34 | 16,725
Male tissues 33 | 17,142
Respiratory system 33 | 16,393
Urinary Tract 33 | 16,678
Cardiovascular System 32 | 15,192

Target Family

Enzyme 36 | 4,145
Non-IDG 1 | 12,091

UniProt Keyword

Rotamase 37 | 37
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peptidyl-prolyl cis-trans isomerase G PPIG Tchem Enzyme -3.69407 4421.0 219
Serine/threonine-protein phosphatase 2A activator PTPA Tchem Enzyme -3.25782 1802.5 255
Peptidyl-prolyl cis-trans isomerase A PPIA Tclin Enzyme -2.97822 870.7 436
Peptidyl-prolyl cis-trans isomerase FKBP4 FKBP4 Tchem Enzyme -2.69982 543.3 446
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 Tchem Enzyme -2.44422 522.8 528
Peptidyl-prolyl cis-trans isomerase F, mitochondrial PPIF Tchem Enzyme -2.65404 448.1 252
Peptidyl-prolyl cis-trans isomerase FKBP1A FKBP1A Tclin Enzyme -2.77923 382.8 271
Peptidyl-prolyl cis-trans isomerase FKBP5 FKBP5 Tchem Enzyme -2.52114 348.1 299
Peptidyl-prolyl cis-trans isomerase B PPIB Tchem Enzyme -2.24866 187.1 304
Peptidyl-prolyl cis-trans isomerase FKBP1B FKBP1B Tchem Enzyme -2.09568 114.2 84