Development Level

Tbio 63 | 11,651
Tdark 13 | 6,593
Tchem 3 | 1,388

Collection

Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to o... 4 | 239
abnormal coat-hair pigmentatio... 2 | 64
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
cataract 1 | 92
decreased body length 1 | 101
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased coping response 1 | 8
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hyperactivity 1 | 148
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased mean platelet volume 1 | 45
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 57 | 8,520
Carcinoma 51 | 11,493
lung cancer 34 | 4,740
osteosarcoma 30 | 7,950
group 3 medulloblastoma 26 | 4,104
psoriasis 25 | 6,694
medulloblastoma, large-cell 24 | 6,241
glioblastoma 16 | 5,792
Breast cancer 14 | 3,578
colon cancer 14 | 1,478
Multiple myeloma 13 | 1,332
acute quadriplegic myopathy 13 | 1,158
malignant mesothelioma 11 | 3,232
ependymoma 10 | 4,679
Waldenstrons macroglobulinemia 9 | 765
non-small cell lung cancer 9 | 2,890
Kidney cancer 8 | 2,613
non primary Sjogren syndrome sicca 8 | 891
Dull intelligence 7 | 645
Intellectual disability 7 | 1,016
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
atypical teratoid / rhabdoid tumor 7 | 5,112
lung adenocarcinoma 7 | 2,716
Autosomal recessive predisposition 6 | 1,442
Cancer 6 | 2,499
dermatomyositis 6 | 966
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
Adenocarcinoma of lung 5 | 142
Anemia 5 | 365
Bowen-Conradi syndrome 5 | 16
Cognitive delay 5 | 608
Disease Models, Animal 5 | 155
Global developmental delay 5 | 608
Hemoglobin low 5 | 124
Mental and motor retardation 5 | 608
Short stature 5 | 531
Shwachman-Diamond syndrome 5 | 17
adult high grade glioma 5 | 3,801
diabetes mellitus 5 | 1,728
juvenile dermatomyositis 5 | 1,187
oligodendroglioma 5 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
Astrocytoma, Pilocytic 4 | 3,081
Decreased platelet count 4 | 111
Dyskeratosis congenita 4 | 24
Malabsorption 4 | 82
Osteoporosis 4 | 363
Skin Ulcer 4 | 48
Small head 4 | 374
Thrombocytopenia 4 | 197
astrocytic glioma 4 | 2,597
astrocytoma 4 | 1,146
gastric carcinoma 4 | 807
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
primitive neuroectodermal tumor 4 | 3,035
sonic hedgehog group medulloblastoma 4 | 467
Abnormal blistering of the skin 3 | 54
Blister of skin 3 | 54
Blood Coagulation Disorders 3 | 42
Cellular immunodeficiency 3 | 17
Coagulation abnormalities 3 | 27
Dental caries 3 | 164
Dystrophia unguium 3 | 53
Esophageal Stenosis 3 | 15
Failure to gain weight 3 | 365
Frequent fractures 3 | 53
Gaucher disease type 1 3 | 180
Gingival Diseases 3 | 19
HIV Infections 3 | 102
Hemorrhagic Disorders 3 | 30
Hyperhidrosis disorder 3 | 81
Hyperpigmentation 3 | 37
Hypodontia 3 | 81
Increased fracture rate 3 | 53
Increased sweating 3 | 81
Leukoplakia, Oral 3 | 20
Liver Cirrhosis 3 | 181
Neutrophil abnormality 3 | 20
Pancytopenia 3 | 45
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Recurrent respiratory infections 3 | 141
Skin bulla 3 | 54
Sparse hair 3 | 59
Sweating 3 | 81
Telangiectasia of the skin 3 | 39
Thin, sparse hair 3 | 59
Varying degree of multiple fractures 3 | 53
active Crohn's disease 3 | 922
ductal carcinoma in situ 3 | 1,745
hereditary spastic paraplegia 3 | 318
hypopigmented skin patch 3 | 59
periodontitis 3 | 293
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Blood and immune system 79 | 16,909
Cardiovascular System 79 | 15,192
Digestive Tract 79 | 17,369
Endocrine System 79 | 18,159
Female tissues 79 | 17,400
Liver and Pancreas 79 | 16,750
Male tissues 79 | 17,142
Nervous System 79 | 16,725
Respiratory system 79 | 16,393
Skin and soft tissues 79 | 17,230
Urinary Tract 79 | 16,678

Target Family

Non-IDG 54 | 12,091
Enzyme 19 | 4,145
Kinase 3 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

UniProt Keyword

Ribosome biogenesis 79 | 79
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTP-binding protein 10 GTPBP10 Tdark Non-IDG -0.23899 1.73 121
H/ACA ribonucleoprotein complex subunit 1 GAR1 Tbio Non-IDG -0.33131 2.70 86
mRNA turnover protein 4 homolog MRTO4 Tbio Non-IDG -1.05881 10.9 175
Probable rRNA-processing protein EBP2 EBNA1BP2 Tbio Non-IDG -1.54043 34.9 87
U3 small nucleolar ribonucleoprotein protein IMP3 IMP3 Tbio Non-IDG -0.34242 1.83 146
FAST kinase domain-containing protein 2, mitochondrial FASTKD2 Tbio Enzyme -0.76901 6.84 141
U3 small nucleolar RNA-associated protein 14 homolog C UTP14C Tdark Non-IDG -0.60025 4.82 16
U3 small nucleolar RNA-associated protein 14 homolog A UTP14A Tdark Non-IDG -0.59151 4.35 107
Bystin BYSL Tbio Non-IDG -1.23828 16.6 66
Ribosome biogenesis protein NOP53 NOP53 Tbio Non-IDG -1.35132 27.1 155