Development Level

Tbio 108 | 11,651
Tdark 71 | 6,593
Tchem 2 | 1,388

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 15 | 979
embryonic lethality prior to o... 8 | 239
embryonic lethality prior to t... 6 | 278
abnormal embryo size 4 | 220
embryonic growth retardation 4 | 106
abnormal bone structure 2 | 187
decreased circulating glucose ... 2 | 126
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal tail morphology 1 | 25
decreased circulating sodium l... 1 | 22
impaired pupillary reflex 1 | 26
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38

Disease

ovarian cancer 89 | 8,520
lung cancer 53 | 4,740
osteosarcoma 46 | 7,950
Multiple myeloma 37 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
medulloblastoma, large-cell 31 | 6,241
diabetes mellitus 30 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,962
Carcinoma 26 | 11,493
psoriasis 26 | 6,694
Diamond-Blackfan anemia 25 | 31
Breast cancer 22 | 3,578
atypical teratoid / rhabdoid tumor 22 | 5,112
glioblastoma 22 | 5,792
group 3 medulloblastoma 21 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
acute myeloid leukemia 19 | 783
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
Waldenstrons macroglobulinemia 17 | 765
non primary Sjogren syndrome sicca 16 | 891
Breast Neoplasms 14 | 445
Cleft Palate 14 | 271
Mammary Neoplasms 14 | 425
non-small cell lung cancer 14 | 2,890
Abnormality of the urinary system 13 | 21
Anemia 13 | 365
Anemia, Diamond-Blackfan 13 | 16
Anemia, Macrocytic 13 | 18
Cardiac Arrhythmia 13 | 103
Cardiac conduction abnormalities 13 | 78
Conduction disorder of the heart 13 | 79
Delayed Puberty 13 | 97
EKG abnormalities 13 | 78
Electrocardiogram abnormal 13 | 81
Electrocardiogram change 13 | 78
Fatigue 13 | 182
Hand deformities 13 | 32
Intermittent migraine headaches 13 | 68
Migraine Disorders 13 | 76
Pallor 13 | 40
Uranostaphyloschisis 13 | 167
cystic fibrosis 13 | 1,696
genital abnormal 13 | 17
malignant mesothelioma 13 | 3,232
reproductive system abnormality 13 | 17
Disease Progression 11 | 136
Stomach Neoplasms 11 | 300
acute quadriplegic myopathy 11 | 1,158
adult high grade glioma 11 | 3,801
colon cancer 11 | 1,478
invasive ductal carcinoma 11 | 2,951
oligodendroglioma 11 | 2,850
sonic hedgehog group medulloblastoma 11 | 467
astrocytic glioma 10 | 2,597
lung adenocarcinoma 10 | 2,716
pediatric high grade glioma 10 | 1,064
subependymal giant cell astrocytoma 9 | 2,287
ependymoma 8 | 4,679
Adenocarcinoma of lung 7 | 142
Disease Models, Animal 7 | 155
primitive neuroectodermal tumor 7 | 3,035
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
mucosa-associated lymphoid tissue lymphoma 6 | 484
Astrocytoma, Pilocytic 5 | 3,081
Cancer 5 | 2,499
Pick disease 5 | 1,894
Reticulocytopenia 5 | 10
group 4 medulloblastoma 5 | 1,855
lung carcinoma 5 | 2,843
Brain glioma 4 | 7
Hereditary spherocytosis type 4 4 | 18
Infantile onset 4 | 238
Parkinson Disease 4 | 64
inflammatory breast cancer 4 | 286
Acquired metabolic disease 3 | 336
Animal Mammary Neoplasms 3 | 136
Autosomal recessive predisposition 3 | 1,442
Cardiovascular system disease 3 | 246
Duchenne muscular dystrophy 3 | 601
Hereditary spherocytosis type 1 3 | 23
Mammary Neoplasms, Animal 3 | 136
Mammary Neoplasms, Experimental 3 | 154
Osteoporosis 3 | 363
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
Retinitis pigmentosa 49 3 | 14
Rheumatoid arthritis 3 | 1,191
Shwachman-Diamond syndrome 3 | 17
Ventricular Septal Defects 3 | 119
Weight Gain 3 | 100
active Crohn's disease 3 | 922
adrenocortical carcinoma 3 | 1,428
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
nasopharyngeal carcinoma 3 | 1,058
posterior fossa group A ependymoma 3 | 468
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 173 | 18,159
Blood and immune system 172 | 16,909
Digestive Tract 172 | 17,369
Male tissues 172 | 17,142
Skin and soft tissues 172 | 17,230
Cardiovascular System 171 | 15,192
Female tissues 171 | 17,400
Liver and Pancreas 171 | 16,750
Nervous System 171 | 16,725
Respiratory system 171 | 16,393
Urinary Tract 171 | 16,678

Target Family

Non-IDG 176 | 12,091
Enzyme 4 | 4,145
Kinase 1 | 634

UniProt Keyword

Ribosomal protein 181 | 181
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
28S ribosomal protein S14, mitochondrial MRPS14 Tdark Non-IDG 0.30 0.11 22
60S ribosomal protein L17 RPL17 Tbio Non-IDG -1.22337 16.5 217
39S ribosomal protein L40, mitochondrial MRPL40 Tbio Non-IDG -0.92179 8.33 105
39S ribosomal protein L42, mitochondrial MRPL42 Tdark Non-IDG 0.02 0.40 139
28S ribosomal protein S18b, mitochondrial MRPS18B Tdark Non-IDG -0.67793 4.10 45
Aurora kinase A-interacting protein AURKAIP1 Tchem Enzyme -0.07918 1.93 59
39S ribosomal protein S18a, mitochondrial MRPS18A Tdark Non-IDG 0.32 0.72 57
60S ribosomal protein L7-like 1 RPL7L1 Tdark Non-IDG 0.41 0.39 57
39S ribosomal protein L16, mitochondrial MRPL16 Tdark Non-IDG -0.22185 1.67 71
60S ribosomal protein L6 RPL6 Tbio Non-IDG -1.58528 37.8 68