Development Level

Tbio 537 | 11,651
Tdark 519 | 6,593
Tclin 227 | 612
Tchem 219 | 1,388

Collection

GPCR: IDG Consortium (Targets) 124 | 126
RFA-RM-18-021 113 | 328
GPCR: IDG Consortium (Complete... 25 | 25
Ion Channel: IDG Consortium (T... 13 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 35 | 979
preweaning lethality, incomple... 31 | 499
decreased vertical activity 28 | 208
enlarged heart 22 | 210
abnormal behavior 17 | 298
abnormal bone structure 16 | 187
decreased total body fat amoun... 16 | 207
embryonic lethality prior to t... 15 | 278
abnormal heart morphology 14 | 162
abnormal seminal vesicle morph... 13 | 114
decreased bone mineral content 12 | 151
increased lean body mass 11 | 172
decreased heart weight 10 | 27
increased total body fat amoun... 10 | 134
abnormal embryo size 9 | 220
hyperactivity 9 | 148
improved glucose tolerance 9 | 79
increased bone mineral content 9 | 108
increased circulating choleste... 9 | 66
abnormal gait 8 | 69
abnormal kidney morphology 8 | 65
decreased body weight 8 | 161
decreased lean body mass 8 | 135
decreased startle reflex 8 | 75
embryonic lethality prior to o... 8 | 239
impaired glucose tolerance 8 | 75
increased or absent threshold ... 8 | 101
increased startle reflex 8 | 112
small superior vagus ganglion 8 | 74
abnormal epididymis morphology 7 | 42
abnormal eye morphology 7 | 68
decreased bone mineral density 7 | 126
decreased mean corpuscular vol... 7 | 79
decreased prepulse inhibition 7 | 82
increased circulating sodium l... 7 | 71
increased mean corpuscular vol... 7 | 92
prolonged QT interval 7 | 38
decreased circulating glucose ... 6 | 126
decreased lymphocyte cell numb... 6 | 83
female infertility 6 | 60
hypoactivity 6 | 132
increased circulating HDL chol... 6 | 80
increased circulating triglyce... 6 | 42
increased hemoglobin content 6 | 45
increased leukocyte cell numbe... 6 | 47
limb grasping 6 | 41
abnormal pericardium morpholog... 5 | 26
abnormal sleep behavior 5 | 70
cataract 5 | 92
decreased grip strength 5 | 116
decreased leukocyte cell numbe... 5 | 73
increased circulating alkaline... 5 | 122
increased circulating creatini... 5 | 38
increased fasted circulating g... 5 | 76
male infertility 5 | 123
prolonged ST segment 5 | 36
abnormal behavioral response t... 4 | 66
abnormal eye anterior chamber ... 4 | 9
abnormal skin morphology 4 | 50
cardiovascular system phenotyp... 4 | 36
decreased blood urea nitrogen ... 4 | 51
decreased circulating alanine ... 4 | 47
decreased fasted circulating g... 4 | 65
decreased mean corpuscular hem... 4 | 50
decreased neutrophil cell numb... 4 | 42
embryonic growth retardation 4 | 106
enlarged epididymis 4 | 31
increased bone mineral density 4 | 72
increased lymphocyte cell numb... 4 | 32
increased monocyte cell number 4 | 63
increased neutrophil cell numb... 4 | 46
pale yolk sac 4 | 25
small testis 4 | 58
tremors 4 | 39
abnormal embryo turning 3 | 31
abnormal midbrain development 3 | 20
abnormal neural tube closure 3 | 46
abnormal skin coloration 3 | 25
abnormal spleen morphology 3 | 55
absent pinna reflex 3 | 23
decreased T cell number 3 | 15
decreased body length 3 | 101
decreased circulating alkaline... 3 | 46
decreased circulating choleste... 3 | 93
decreased circulating creatini... 3 | 39
decreased circulating serum al... 3 | 82
decreased circulating triglyce... 3 | 79
decreased hemoglobin content 3 | 68
enlarged lymph nodes 3 | 37
hydrometra 3 | 53
increased circulating calcium ... 3 | 34
increased circulating chloride... 3 | 41
increased circulating iron lev... 3 | 30
increased circulating total pr... 3 | 28
increased erythrocyte cell num... 3 | 39
increased heart weight 3 | 62
increased hematocrit 3 | 46
microphthalmia 3 | 26
pallor 3 | 34
short tibia 3 | 97

Disease

Carcinoma 1,095 | 11,493
psoriasis 489 | 6,694
osteosarcoma 476 | 7,950
ovarian cancer 409 | 8,520
medulloblastoma, large-cell 378 | 6,241
glioblastoma 355 | 5,792
lung cancer 355 | 4,740
atypical teratoid / rhabdoid tumor 296 | 5,112
lung carcinoma 293 | 2,843
Cancer 274 | 2,499
interstitial cystitis 264 | 2,312
ependymoma 261 | 4,679
adult high grade glioma 258 | 3,801
Astrocytoma, Pilocytic 238 | 3,081
Breast cancer 230 | 3,578
Kidney cancer 227 | 2,613
non-small cell lung cancer 225 | 2,890
invasive ductal carcinoma 224 | 2,951
lung adenocarcinoma 223 | 2,716
group 3 medulloblastoma 218 | 4,104
malignant mesothelioma 213 | 3,232
diabetes mellitus 196 | 1,728
ulcerative colitis 183 | 1,819
intraductal papillary-mucinous neoplasm (IPMN) 182 | 3,291
Schizophrenia 181 | 1,160
tuberculosis 175 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 173 | 2,955
pancreatic cancer 172 | 2,398
primitive neuroectodermal tumor 171 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 167 | 2,989
oligodendroglioma 165 | 2,850
pituitary cancer 154 | 1,972
ductal carcinoma in situ 147 | 1,745
astrocytic glioma 145 | 2,597
subependymal giant cell astrocytoma 139 | 2,287
cutaneous lupus erythematosus 137 | 1,057
Autosomal recessive predisposition 128 | 1,442
breast carcinoma 124 | 1,638
cystic fibrosis 116 | 1,696
Bipolar Disorder 111 | 666
colon cancer 109 | 1,478
Rheumatoid arthritis 97 | 1,191
group 4 medulloblastoma 96 | 1,855
adrenocortical carcinoma 95 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 91 | 1,962
Depressive disorder 90 | 409
Obesity 90 | 678
Pick disease 85 | 1,894
Melanoma 82 | 711
Epilepsy 79 | 792
astrocytoma 79 | 1,146
Multiple Sclerosis 78 | 540
Asthma 76 | 385
primary Sjogren syndrome 76 | 735
mucosa-associated lymphoid tissue lymphoma 73 | 484
Alcoholic Intoxication, Chronic 72 | 289
Mental Depression 71 | 333
Skin cancer 69 | 469
Alzheimer's disease 68 | 658
Atopic dermatitis 66 | 952
gastric carcinoma 66 | 807
Liver cancer 65 | 604
primary pancreatic ductal adenocarcinoma 63 | 1,109
Liver Cirrhosis, Experimental 62 | 769
Major Depressive Disorder 62 | 301
pediatric high grade glioma 61 | 1,064
Endometriosis 59 | 540
nasopharyngeal carcinoma 55 | 1,058
Autistic Disorder 53 | 364
Hypertension 53 | 396
Mood Disorders 53 | 184
esophageal adenocarcinoma 53 | 737
spina bifida 53 | 1,074
Hypersensitivity reaction type II disease 51 | 253
Intellectual disability 51 | 1,016
fibroadenoma 51 | 559
pancreatic carcinoma 51 | 562
Seizures 49 | 596
juvenile dermatomyositis 49 | 1,187
Atherosclerosis 48 | 291
active Crohn's disease 48 | 922
Kidney disease 47 | 430
Parkinson's disease 47 | 392
Unipolar Depression 47 | 250
acute quadriplegic myopathy 47 | 1,158
non primary Sjogren syndrome sicca 47 | 891
Breast Neoplasms 45 | 445
Duchenne muscular dystrophy 45 | 601
Prostatic Neoplasms 45 | 495
non-small cell lung carcinoma 45 | 317
Mammary Neoplasms 44 | 425
active ulcerative colitis 42 | 764
medulloblastoma 42 | 720
Dull intelligence 41 | 645
Low intelligence 41 | 645
Mental Retardation 41 | 645
Mental deficiency 41 | 645
Poor school performance 41 | 645
Cerebrovascular disease 40 | 238
dermatomyositis 40 | 966

Tissue

Endocrine System 1,093 | 18,159
Female tissues 991 | 17,400
Digestive Tract 973 | 17,369
Skin and soft tissues 956 | 17,230
Blood and immune system 953 | 16,909
Male tissues 950 | 17,142
Nervous System 937 | 16,725
Urinary Tract 911 | 16,678
Liver and Pancreas 908 | 16,750
Respiratory system 884 | 16,393
Cardiovascular System 788 | 15,192

Target Family

Non-IDG 451 | 12,091
oGPCR 421 | 421
GPCR 405 | 408
Kinase 70 | 634
Ion Channel 69 | 344
Nuclear Receptor 48 | 48
Enzyme 26 | 4,145
Transporter 10 | 473
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

UniProt Keyword

Receptor 1,502 | 1,502
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Olfactory receptor 5H15 OR5H15 Tdark oGPCR 0.00000 35
Olfactory receptor 7D2 OR7D2 Tdark oGPCR 0.00000 2
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
CMRF35-like molecule 9 CD300LG Tdark Non-IDG -0.92828 10.3 49
Leukotriene B4 receptor 1 LTB4R Tchem GPCR -2.74171 557.6 365
Long-wave-sensitive opsin 1 OPN1LW Tbio GPCR -2.37983 238.7 47
Medium-wave-sensitive opsin 1 OPN1MW Tbio GPCR -0.97721 8.41 18
T-cell surface glycoprotein CD3 zeta chain CD247 Tbio Non-IDG -2.61157 386.3 882
Olfactory receptor 5B21 OR5B21 Tdark oGPCR 0.00000 4