Development Level

Tbio 49 | 11,445
Tdark 5 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal behavior 2 | 298
decreased mean corpuscular vol... 2 | 79
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
absent spleen 1 | 3
decreased IgE level 1 | 6
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased mean corpuscular hem... 1 | 50
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
hyperactivity 1 | 148
increased grip strength 1 | 41
increased heart weight 1 | 62
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
shortened RR interval 1 | 17

Disease

Carcinoma 42 | 11,493
osteosarcoma 25 | 7,950
medulloblastoma, large-cell 22 | 6,241
ovarian cancer 22 | 8,520
atypical teratoid / rhabdoid tumor 19 | 5,112
ependymoma 18 | 4,679
group 3 medulloblastoma 18 | 4,104
glioblastoma 17 | 5,792
primitive neuroectodermal tumor 17 | 3,035
Kidney cancer 16 | 2,613
psoriasis 16 | 6,694
Breast cancer 14 | 3,578
astrocytic glioma 14 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
oligodendroglioma 14 | 2,850
Cancer 12 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung cancer 10 | 4,740
malignant mesothelioma 10 | 3,232
Pick disease 9 | 1,894
group 4 medulloblastoma 9 | 1,855
juvenile dermatomyositis 8 | 1,187
Male infertility 7 | 206
acute quadriplegic myopathy 7 | 1,158
breast carcinoma 7 | 1,638
Astrocytoma, Pilocytic 6 | 3,081
Infertility 6 | 188
adult high grade glioma 6 | 3,801
astrocytoma 6 | 1,146
non-small cell lung cancer 6 | 2,890
Liver cancer 5 | 604
Multiple myeloma 5 | 1,332
Rheumatoid arthritis 5 | 1,191
dermatomyositis 5 | 966
lung adenocarcinoma 5 | 2,716
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
progressive supranuclear palsy 5 | 676
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic lateral sclerosis 4 | 451
medulloblastoma 4 | 720
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
tuberculosis 4 | 2,010
tuberculosis and treatment for 6 months 4 | 409
Alzheimer's disease 3 | 658
Attention deficit hyperactivity disorder 3 | 278
Azoospermia 3 | 110
Bipolar Disorder 3 | 666
Chikungunya 3 | 16
Gaucher disease type 1 3 | 180
Klinefelter's syndrome 3 | 56
Oligospermia 3 | 36
Schizophrenia 3 | 1,160
Waldenstrons macroglobulinemia 3 | 765
Wilms Tumor 3 | 28
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
atypical teratoid/rhabdoid tumor 3 | 357
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
sarcoidosis 3 | 370
ulcerative colitis 3 | 1,819
Abnormality of metabolism/homeostasis 2 | 134
Alcoholic Intoxication, Chronic 2 | 289
Autosomal recessive predisposition 2 | 1,442
Bradykinesia 2 | 34
Craniofacial Abnormalities 2 | 151
Crohn's disease 2 | 321
Depressive disorder 2 | 409
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Dysarthria 2 | 192
Epilepsy 2 | 792
Fragile X syndrome 2 | 34
Major Depressive Disorder 2 | 301
Mesothelioma, Malignant 2 | 105
Microsatellite Instability 2 | 12
Muscle Rigidity 2 | 49
Neoplasm Invasiveness 2 | 161
Parkinsonian Disorders 2 | 56
Polycystic ovary syndrome 2 | 360
Premature ovarian failure 2 | 65
Unipolar Depression 2 | 250
aldosterone-producing adenoma 2 | 665
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
inflammatory breast cancer 2 | 286
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis and treatment for 3 months 2 | 179

Tissue

Endocrine System 54 | 18,159
Female tissues 52 | 17,400
Digestive Tract 51 | 17,369
Nervous System 51 | 16,725
Blood and immune system 50 | 16,909
Male tissues 49 | 17,142
Respiratory system 49 | 16,393
Skin and soft tissues 49 | 17,230
Urinary Tract 47 | 16,678
Liver and Pancreas 46 | 16,750
Cardiovascular System 45 | 15,192

Target Family

Non-IDG 34 | 12,091
Enzyme 13 | 4,145
Epigenetic 5 | 242
Transcription Factor 2 | 1,400
Kinase 1 | 634

UniProt Keyword

RNA-mediated gene silencing 55 | 55
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CCR4-NOT transcription complex subunit 1 CNOT1 Tbio Non-IDG -2.10799 119.0 37
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 ASZ1 Tbio Non-IDG -2.81661 644.9 107
Putative helicase MOV-10 MOV10 Tbio Enzyme -1.55297 38.5 121
Protein argonaute-4 AGO4 Tbio Non-IDG -1.42077 23.0 121
ATP-dependent RNA helicase TDRD9 TDRD9 Tbio Epigenetic -0.66287 3.88 43
Protein lin-28 homolog B LIN28B Tbio Transcription Factor -2.08968 113.4 204
CCR4-NOT transcription complex subunit 2 CNOT2 Tbio Non-IDG -2.83887 627.5 303
Terminal uridylyltransferase 4 ZCCHC11 Tbio Enzyme -1.18900 14.5 147
ATP-dependent RNA helicase A DHX9 Tbio Enzyme -2.85807 734.3 204
3'-5' exoribonuclease 1 ERI1 Tbio Enzyme -1.96395 87.8 172