Development Level

Tbio 543 | 11,651
Tdark 116 | 6,593
Tchem 19 | 1,388
Tclin 4 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 71 | 979
embryonic lethality prior to o... 25 | 239
embryonic lethality prior to t... 23 | 278
preweaning lethality, incomple... 16 | 499
abnormal embryo size 14 | 220
abnormal behavior 9 | 298
embryonic growth retardation 8 | 106
enlarged heart 8 | 210
increased lean body mass 7 | 172
increased mean corpuscular vol... 7 | 92
abnormal bone structure 6 | 187
hyperactivity 6 | 148
hypoactivity 6 | 132
increased mean platelet volume 6 | 45
decreased circulating choleste... 5 | 93
decreased neutrophil cell numb... 5 | 42
decreased total body fat amoun... 5 | 207
decreased vertical activity 5 | 208
increased fasted circulating g... 5 | 76
increased mean corpuscular hem... 5 | 96
increased startle reflex 5 | 112
abnormal coat-hair pigmentatio... 4 | 64
abnormal heart morphology 4 | 162
decreased caudal vertebrae num... 4 | 53
decreased grip strength 4 | 116
decreased mean corpuscular hem... 4 | 31
decreased mean corpuscular vol... 4 | 79
female infertility 4 | 60
increased bone mineral content 4 | 108
increased grip strength 4 | 41
increased lymphocyte cell numb... 4 | 32
male infertility 4 | 123
prenatal lethality prior to he... 4 | 87
abnormal kidney morphology 3 | 65
abnormal retina morphology 3 | 71
cataract 3 | 92
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 68
decreased circulating alkaline... 3 | 46
decreased circulating glucose ... 3 | 126
decreased circulating triglyce... 3 | 79
decreased fasted circulating g... 3 | 65
decreased heart left ventricle... 3 | 28
increased bone mineral density 3 | 72
increased heart weight 3 | 62
increased total body fat amoun... 3 | 134
abnormal cornea morphology 2 | 31
abnormal embryo turning 2 | 31
abnormal lens morphology 2 | 81
abnormal lung morphology 2 | 26
abnormal pericardium morpholog... 2 | 26
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
abnormal vitreous body morphol... 2 | 10
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased circulating calcium ... 2 | 36
decreased circulating chloride... 2 | 30
decreased circulating phosphat... 2 | 27
decreased circulating serum al... 2 | 82
decreased erythrocyte cell num... 2 | 62
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased red blood cell distr... 2 | 41
edema 2 | 59
impaired glucose tolerance 2 | 75
increased body length 2 | 32
increased circulating chloride... 2 | 41
increased hematocrit 2 | 46
increased or absent threshold ... 2 | 101
short tibia 2 | 97
small testis 2 | 58
thin ventricular wall 2 | 24
tremors 2 | 39
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal liver morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal retinal vasculature m... 1 | 27
abnormal spleen morphology 1 | 55
absent spleen 1 | 3
decreased IgE level 1 | 6
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased eosinophil cell numb... 1 | 24
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased total retina thickne... 1 | 17
increased circulating alkaline... 1 | 122
increased circulating fructosa... 1 | 13
increased circulating triglyce... 1 | 42
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28

Disease

Carcinoma 434 | 11,493
ovarian cancer 382 | 8,520
osteosarcoma 331 | 7,950
medulloblastoma, large-cell 250 | 6,241
psoriasis 226 | 6,694
group 3 medulloblastoma 221 | 4,104
glioblastoma 217 | 5,792
lung cancer 211 | 4,740
atypical teratoid / rhabdoid tumor 202 | 5,112
ependymoma 174 | 4,679
primitive neuroectodermal tumor 135 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 134 | 3,291
Breast cancer 130 | 3,578
oligodendroglioma 130 | 2,850
Multiple myeloma 127 | 1,332
malignant mesothelioma 123 | 3,232
adult high grade glioma 115 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 111 | 2,989
astrocytic glioma 108 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 102 | 2,955
Pick disease 99 | 1,894
Kidney cancer 95 | 2,613
acute quadriplegic myopathy 93 | 1,158
lung adenocarcinoma 88 | 2,716
subependymal giant cell astrocytoma 85 | 2,287
Waldenstrons macroglobulinemia 83 | 765
juvenile dermatomyositis 83 | 1,187
dermatomyositis 82 | 966
Cancer 80 | 2,499
invasive ductal carcinoma 78 | 2,951
Astrocytoma, Pilocytic 77 | 3,081
non-small cell lung cancer 69 | 2,890
pancreatic cancer 69 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 69 | 1,962
astrocytoma 63 | 1,146
group 4 medulloblastoma 62 | 1,855
diabetes mellitus 57 | 1,728
lung carcinoma 57 | 2,843
progressive supranuclear palsy 56 | 676
tuberculosis 50 | 2,010
Rheumatoid arthritis 49 | 1,191
breast carcinoma 49 | 1,638
pediatric high grade glioma 47 | 1,064
colon cancer 46 | 1,478
cystic fibrosis 46 | 1,696
pituitary cancer 44 | 1,972
acute myeloid leukemia 43 | 783
Amyotrophic lateral sclerosis 42 | 451
Intellectual disability 39 | 1,016
adrenocortical carcinoma 37 | 1,428
spina bifida 37 | 1,074
non primary Sjogren syndrome sicca 36 | 891
ulcerative colitis 36 | 1,819
Schizophrenia 34 | 1,160
ductal carcinoma in situ 34 | 1,745
Autosomal recessive predisposition 33 | 1,442
aldosterone-producing adenoma 33 | 665
hepatocellular carcinoma 33 | 547
primary pancreatic ductal adenocarcinoma 33 | 1,109
tuberculosis and treatment for 6 months 32 | 409
cutaneous lupus erythematosus 27 | 1,057
nasopharyngeal carcinoma 27 | 1,058
primary Sjogren syndrome 27 | 735
sonic hedgehog group medulloblastoma 26 | 467
interstitial cystitis 25 | 2,312
Multiple Sclerosis 24 | 540
Alzheimer's disease 23 | 658
Cognitive delay 23 | 608
Global developmental delay 23 | 608
Mental and motor retardation 23 | 608
Infertility 22 | 188
Male infertility 22 | 206
gastric carcinoma 22 | 807
pancreatic carcinoma 22 | 562
Breast Neoplasms 21 | 445
Neurodegenerative disease 21 | 414
Dull intelligence 19 | 645
Low intelligence 19 | 645
Mental Retardation 19 | 645
Mental deficiency 19 | 645
Poor school performance 19 | 645
active Crohn's disease 19 | 922
hereditary spastic paraplegia 19 | 318
interstitial lung disease 19 | 298
Atopic dermatitis 18 | 952
Gaucher disease type 1 18 | 180
Influenza 18 | 142
medulloblastoma 18 | 720
Mammary Neoplasms 17 | 425
Systemic lupus erythematosus 17 | 194
atypical teratoid/rhabdoid tumor 17 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 510
Epilepsy 16 | 792
gastric cancer 16 | 459
Azoospermia 15 | 110
Melanoma 15 | 711
Small head 15 | 374
relapsing-remitting multiple sclerosis 15 | 18
Muscle hypotonia 14 | 571
Short stature 14 | 531

Tissue

Endocrine System 662 | 18,159
Digestive Tract 643 | 17,369
Male tissues 642 | 17,142
Skin and soft tissues 640 | 17,230
Female tissues 638 | 17,400
Nervous System 635 | 16,725
Blood and immune system 634 | 16,909
Respiratory system 634 | 16,393
Liver and Pancreas 631 | 16,750
Urinary Tract 628 | 16,678
Cardiovascular System 617 | 15,192

Target Family

Non-IDG 480 | 12,091
Enzyme 168 | 4,145
Transcription Factor 15 | 1,400
Epigenetic 11 | 242
Kinase 6 | 634
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

RNA-binding 682 | 682
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/arginine-rich splicing factor 12 SRSF12 Tbio Non-IDG -0.09691 1.17 22
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Zinc finger protein 346 ZNF346 Tbio Non-IDG -2.28393 188.7 213
Heterogeneous nuclear ribonucleoprotein C-like 2 HNRNPCL2 Tdark Non-IDG 0.33 1.30 0
Poly(A)-specific ribonuclease PARN PARN Tbio Enzyme -1.87605 76.4 263
RING finger protein unkempt homolog UNK Tbio Non-IDG -2.53936 348.0 64
Nucleolysin TIA-1 isoform p40 TIA1 Tbio Non-IDG -2.86461 714.2 314
Eukaryotic translation initiation factor 2 subunit 1 EIF2S1 Tbio Non-IDG -2.81111 643.5 577
RNA-binding protein 39 RBM39 Tbio Non-IDG -0.95639 9.80 199
Poly(A) polymerase beta PAPOLB Tbio Enzyme -1.66566 44.9 59