Development Level

Tbio 491 | 10,625
Tdark 136 | 7,003
Tchem 32 | 1,890
Tclin 4 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 42 | 633
embryonic lethality prior to o... 14 | 148
embryonic lethality prior to t... 13 | 187
preweaning lethality, incomple... 10 | 260
abnormal behavior 7 | 226
abnormal embryo size 7 | 112
hyperactivity 6 | 108
decreased body length 5 | 108
increased grip strength 5 | 83
abnormal retina morphology 4 | 100
decreased circulating HDL chol... 4 | 77
decreased circulating choleste... 4 | 85
decreased grip strength 4 | 123
decreased lean body mass 4 | 195
decreased rib number 4 | 59
increased circulating alkaline... 4 | 119
increased fasted circulating g... 4 | 68
increased mean corpuscular hem... 4 | 93
increased mean corpuscular vol... 4 | 91
increased or absent threshold ... 4 | 128
abnormal coat/hair pigmentatio... 3 | 54
abnormal rib morphology 3 | 28
decreased body weight 3 | 174
decreased lumbar vertebrae num... 3 | 62
decreased total body fat amoun... 3 | 186
enlarged heart 3 | 111
increased startle reflex 3 | 38
prenatal lethality prior to he... 3 | 64
abnormal bone structure 2 | 131
abnormal cornea morphology 2 | 24
abnormal joint morphology 2 | 14
abnormal lens morphology 2 | 73
abnormal lung morphology 2 | 15
abnormal neural tube closure 2 | 37
abnormal retinal outer nuclear... 2 | 5
abnormal retinal pigmentation 2 | 61
decreased CD4-positive, CD25-p... 2 | 24
decreased KLRG1-positive NK ce... 2 | 9
decreased NK cell number 2 | 16
decreased bone mineral content 2 | 157
decreased caudal vertebrae num... 2 | 49
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating alkaline... 2 | 41
decreased circulating chloride... 2 | 32
decreased circulating glucose ... 2 | 121
decreased fasted circulating g... 2 | 49
decreased leukocyte cell numbe... 2 | 54
increased bone mineral content 2 | 92
increased circulating HDL chol... 2 | 63
increased circulating chloride... 2 | 43
increased exploration in new e... 2 | 56
increased mean platelet volume 2 | 19
increased sacral vertebrae num... 2 | 62
polydactyly 2 | 22
abnormal cranium morphology 1 | 32
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal snout morphology 1 | 18
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
decreased KLRG1+ CD4 alpha bet... 1 | 2
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 33
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased gamma-delta T cell n... 1 | 18
decreased heart weight 1 | 44
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased threshold for audito... 1 | 32
decreased total retina thickne... 1 | 20
dilated heart left ventricle 1 | 10
embryonic growth retardation 1 | 28
female infertility 1 | 34
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
increased NK cell number 1 | 19
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating amylase ... 1 | 13
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating potassiu... 1 | 31
increased granulocyte number 1 | 8
increased lean body mass 1 | 107
increased total body fat amoun... 1 | 57
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
short tibia 1 | 82
small testis 1 | 37
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

ovarian cancer 369 | 8,484
osteosarcoma 321 | 7,933
medulloblastoma, large-cell 241 | 6,234
psoriasis 218 | 6,685
glioblastoma 203 | 5,572
lung cancer 198 | 4,466
atypical teratoid / rhabdoid tumor 168 | 4,369
group 3 medulloblastoma 141 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 131 | 3,289
primitive neuroectodermal tumor 129 | 3,031
oligodendroglioma 128 | 2,849
Multiple myeloma 125 | 1,327
ependymoma 117 | 2,514
Breast cancer 116 | 3,094
malignant mesothelioma 114 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 108 | 2,988
pediatric high grade glioma 103 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 100 | 2,956
Pick disease 98 | 1,893
acute quadriplegic myopathy 92 | 1,157
astrocytic glioma 92 | 2,241
lung adenocarcinoma 86 | 2,713
Waldenstrons macroglobulinemia 82 | 765
subependymal giant cell astrocytoma 82 | 2,287
juvenile dermatomyositis 80 | 1,189
dermatomyositis 79 | 933
Cancer 76 | 2,346
astrocytoma 75 | 1,493
invasive ductal carcinoma 75 | 2,950
pilocytic astrocytoma 75 | 3,086
group 4 medulloblastoma 71 | 1,875
sonic hedgehog group medulloblastoma 69 | 1,482
pancreatic cancer 66 | 2,300
non-small cell lung cancer 65 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 63 | 1,795
Carcinoma 58 | 2,147
adult high grade glioma 56 | 2,148
lung carcinoma 55 | 2,844
progressive supranuclear palsy 54 | 674
diabetes mellitus 53 | 1,663
breast carcinoma 47 | 1,614
tuberculosis and treatment for 6 months 47 | 686
atypical teratoid/rhabdoid tumor 46 | 1,095
colon cancer 46 | 1,475
cystic fibrosis 46 | 1,665
Rheumatoid Arthritis 45 | 1,160
pituitary cancer 44 | 1,972
acute myeloid leukemia 43 | 780
Amyotrophic Lateral Sclerosis 39 | 431
posterior fossa group A ependymoma 39 | 1,511
ulcerative colitis 39 | 2,087
adrenocortical carcinoma 36 | 1,427
medulloblastoma 36 | 1,524
spina bifida 36 | 1,064
posterior fossa group B ependymoma 35 | 1,530
primary pancreatic ductal adenocarcinoma 34 | 1,271
ductal carcinoma in situ 33 | 1,745
hepatocellular carcinoma 33 | 532
non primary Sjogren syndrome sicca 33 | 840
aldosterone-producing adenoma 32 | 664
tuberculosis 32 | 1,557
Intellectual disability 29 | 573
primary Sjogren syndrome 29 | 789
nasopharyngeal carcinoma 27 | 1,056
cutaneous lupus erythematosus 26 | 1,056
interstitial cystitis 25 | 2,299
Alzheimer's disease 24 | 644
Multiple Sclerosis 24 | 498
pancreatic carcinoma 22 | 567
Neurodegenerative disease 21 | 383
gastric carcinoma 21 | 832
Infertility 19 | 163
Influenza 19 | 142
active Crohn's disease 19 | 918
hereditary spastic paraplegia 19 | 313
Atopic dermatitis 18 | 944
Mammary Neoplasms 17 | 410
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 499
interstitial lung disease 17 | 291
Gaucher disease type 1 16 | 171
Male infertility 16 | 170
gastric cancer 16 | 430
systemic lupus erythematosus 16 | 156
IGA Glomerulonephritis 15 | 454
Schizophrenia 15 | 501
Azoospermia 14 | 89
Down syndrome 14 | 548
Polycystic Ovary Syndrome 14 | 332
relapsing-remitting multiple sclerosis 14 | 18
Duchenne muscular dystrophy 13 | 602
glioblastoma multiforme 13 | 347
inflammatory breast cancer 13 | 404
sarcoidosis 13 | 358
Endometriosis 12 | 535
HIV Infections 12 | 100
Disease Progression 11 | 125
Prostatic Neoplasms 11 | 471
Stomach Neoplasms 11 | 282
Type 2 diabetes mellitus 11 | 189
mucosa-associated lymphoid tissue lymphoma 11 | 480

Tissue

Female tissues 644 | 18,647
Male tissues 643 | 17,969
Endocrine System 640 | 18,512
Digestive Tract 638 | 18,473
Blood and immune system 636 | 17,995
Urinary Tract 635 | 18,444
Nervous System 634 | 18,561
Liver and Pancreas 633 | 18,136
Cardiovascular System 628 | 17,958
Skin and soft tissues 626 | 18,115
Respiratory system 624 | 17,484

Target Family

Non-IDG 468 | 11,971
Enzyme 163 | 4,146
Transcription Factor 14 | 1,400
Epigenetic 10 | 242
Kinase 6 | 634
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

RNA-binding 663 | 663
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear cap-binding protein subunit 3 NCBP3 Tbio Non-IDG -1.68208 49.3 22
Programmed cell death protein 4 PDCD4 Tchem Non-IDG -2.40380 284.9 546
mRNA decay activator protein ZFP36 ZFP36 Tbio Non-IDG -2.38153 220.3 0
Histone-lysine N-methyltransferase SETD1B SETD1B Tbio Epigenetic -1.20916 14.6 78
CUGBP Elav-like family member 4 CELF4 Tbio Non-IDG -1.46075 29.8 40
Small nuclear ribonucleoprotein F SNRPF Tdark Non-IDG -0.25254 1.81 65
Interleukin enhancer-binding factor 3 ILF3 Tbio Non-IDG -2.09543 135.8 239
Small nuclear ribonucleoprotein G SNRPG Tdark Non-IDG 1.33 95
Serine/arginine repetitive matrix protein 2 SRRM2 Tbio Non-IDG -1.90106 71.6 51
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 AIMP1 Tbio Enzyme -2.04569 136.6 321