Development Level

Tbio 37 | 11,445
Tchem 15 | 1,598
Tdark 7 | 6,588
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
increased bone mineral content 2 | 108
abnormal behavior 1 | 298
abnormal glucose homeostasis 1 | 4
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal tail movements 1 | 12
brachydactyly 1 | 19
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
preweaning lethality, incomple... 1 | 499
syndactyly 1 | 23
thin ventricular wall 1 | 24

Disease

Carcinoma 42 | 11,493
ovarian cancer 31 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,962
psoriasis 25 | 6,694
medulloblastoma, large-cell 24 | 6,241
osteosarcoma 23 | 7,950
glioblastoma 21 | 5,792
group 3 medulloblastoma 19 | 4,104
adult high grade glioma 18 | 3,801
atypical teratoid / rhabdoid tumor 18 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
Autosomal recessive predisposition 16 | 1,442
lung cancer 16 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
ependymoma 14 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
oligodendroglioma 14 | 2,850
Astrocytoma, Pilocytic 13 | 3,081
primitive neuroectodermal tumor 13 | 3,035
Liver Cirrhosis, Experimental 12 | 769
lung carcinoma 12 | 2,843
non-small cell lung cancer 12 | 2,890
tuberculosis 12 | 2,010
Schizophrenia 11 | 1,160
invasive ductal carcinoma 11 | 2,951
pituitary cancer 11 | 1,972
adrenocortical carcinoma 10 | 1,428
interstitial cystitis 10 | 2,312
Breast cancer 9 | 3,578
Cancer 9 | 2,499
Intellectual disability 9 | 1,016
malignant mesothelioma 9 | 3,232
subependymal giant cell astrocytoma 9 | 2,287
Epilepsy 8 | 792
Seizures 8 | 596
lung adenocarcinoma 8 | 2,716
pancreatic cancer 8 | 2,398
Major Depressive Disorder 7 | 301
Bipolar Disorder 6 | 666
Cognitive delay 6 | 608
Dull intelligence 6 | 645
Global developmental delay 6 | 608
Kidney cancer 6 | 2,613
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Poor school performance 6 | 645
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
Down syndrome 5 | 499
Multiple myeloma 5 | 1,332
Pick disease 5 | 1,894
Unipolar Depression 5 | 250
active ulcerative colitis 5 | 764
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
gastric carcinoma 5 | 807
group 4 medulloblastoma 5 | 1,855
nephrosclerosis 5 | 333
pediatric high grade glioma 5 | 1,064
posterior fossa group A ependymoma 5 | 468
ulcerative colitis 5 | 1,819
Adenocarcinoma of lung 4 | 142
Atherosclerosis 4 | 291
Disease Models, Animal 4 | 155
Hyperreflexia 4 | 209
Infantile onset 4 | 238
Neurodegenerative disease 4 | 414
Osteoporosis 4 | 363
aldosterone-producing adenoma 4 | 665
breast carcinoma 4 | 1,638
cutaneous lupus erythematosus 4 | 1,057
esophageal adenocarcinoma 4 | 737
inflammatory breast cancer 4 | 286
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
spina bifida 4 | 1,074
Acquired scoliosis 3 | 281
Alzheimer's disease 3 | 658
Atopic dermatitis 3 | 952
Curvature of spine 3 | 282
Kidney disease 3 | 430
Polycystic ovary syndrome 3 | 360
Primary hyperoxaluria 3 | 15
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
chronic rhinosinusitis 3 | 512
dermatomyositis 3 | 966
hepatocellular carcinoma 3 | 547
mucosa-associated lymphoid tissue lymphoma 3 | 484
pancreatic carcinoma 3 | 562
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676

Tissue

Digestive Tract 60 | 17,369
Liver and Pancreas 60 | 16,750
Skin and soft tissues 60 | 17,230
Endocrine System 59 | 18,159
Female tissues 59 | 17,400
Urinary Tract 59 | 16,678
Blood and immune system 57 | 16,909
Male tissues 57 | 17,142
Nervous System 57 | 16,725
Respiratory system 54 | 16,393
Cardiovascular System 51 | 15,192

Target Family

Enzyme 61 | 4,145
Non-IDG 1 | 12,091

UniProt Keyword

Pyridoxal phosphate 62 | 62
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 Tbio Enzyme -1.80580 61.7 153
Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 Tbio Enzyme -1.47858 32.0 77
Pyridoxine-5'-phosphate oxidase PNPO Tchem Enzyme -1.95803 90.7 200
O-phosphoseryl-tRNA(Sec) selenium transferase SEPSECS Tbio Enzyme -2.11362 120.5 120
1-aminocyclopropane-1-carboxylate synthase-like protein 1 ACCS Tbio Enzyme -2.31602 195.2 154
Formimidoyltransferase-cyclodeaminase FTCD Tbio Enzyme -2.23276 170.0 418
Cysteine desulfurase, mitochondrial NFS1 Tbio Enzyme -1.70267 46.3 131
Cysteine sulfinic acid decarboxylase CSAD Tbio Enzyme -2.16604 143.8 134
Threonine synthase-like 2 THNSL2 Tbio Enzyme -1.56098 37.5 97
Glycine dehydrogenase (decarboxylating), mitochondrial GLDC Tbio Enzyme -1.79392 65.7 131