Development Level

Tbio 153 | 10,625
Tchem 43 | 1,890
Tclin 25 | 602
Tdark 12 | 7,003

IMPC Term

preweaning lethality, complete... 16 | 633
abnormal bone mineralization 3 | 55
decreased bone mineral density 3 | 126
decreased lean body mass 3 | 195
enlarged heart 3 | 111
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal embryo size 2 | 112
decreased body weight 2 | 174
decreased circulating choleste... 2 | 85
decreased erythrocyte cell num... 2 | 43
decreased grip strength 2 | 123
decreased leukocyte cell numbe... 2 | 54
decreased prepulse inhibition 2 | 52
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
hyperactivity 2 | 108
increased blood urea nitrogen ... 2 | 44
increased circulating LDL chol... 2 | 15
increased circulating alkaline... 2 | 119
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
thrombocytopenia 2 | 46
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal femur morphology 1 | 14
abnormal glucose homeostasis 1 | 5
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal tail morphology 1 | 17
absent vibrissae 1 | 14
cataract 1 | 26
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased circulating LDL chol... 1 | 37
decreased circulating iron lev... 1 | 25
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased startle reflex 1 | 48
enlarged lymph nodes 1 | 27
female infertility 1 | 34
hydrops fetalis 1 | 22
hypoactivity 1 | 89
increased circulating HDL chol... 1 | 63
increased circulating amylase ... 1 | 13
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating glucose ... 1 | 16
increased circulating phosphat... 1 | 24
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
limb grasping 1 | 35
no spontaneous movement 1 | 1
prenatal lethality 1 | 16
prolonged QRS complex duration 1 | 2
prolonged RR interval 1 | 2
short tibia 1 | 82
small superior vagus ganglion 1 | 20
thick ventricular wall 1 | 7
thrombocytosis 1 | 23
tremors 1 | 34

Disease

Cancer 229 | 2,346
ovarian cancer 146 | 8,484
osteosarcoma 142 | 7,933
medulloblastoma, large-cell 108 | 6,234
glioblastoma 107 | 5,572
psoriasis 107 | 6,685
lung cancer 98 | 4,466
Breast cancer 82 | 3,094
atypical teratoid / rhabdoid tumor 68 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 64 | 2,988
lung adenocarcinoma 64 | 2,713
invasive ductal carcinoma 63 | 2,950
non-small cell lung cancer 62 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 60 | 3,289
malignant mesothelioma 58 | 3,162
intraductal papillary-mucinous adenoma (IPMA) 55 | 2,956
pancreatic cancer 55 | 2,300
primitive neuroectodermal tumor 55 | 3,031
Carcinoma 53 | 2,147
subependymal giant cell astrocytoma 52 | 2,287
pilocytic astrocytoma 50 | 3,086
oligodendroglioma 49 | 2,849
pediatric high grade glioma 49 | 2,712
lung carcinoma 47 | 2,844
ulcerative colitis 47 | 2,087
pituitary cancer 45 | 1,972
astrocytoma 44 | 1,493
ependymoma 41 | 2,514
interstitial cystitis 39 | 2,299
tuberculosis 38 | 1,557
colon cancer 37 | 1,475
adrenocortical carcinoma 35 | 1,427
breast carcinoma 35 | 1,614
astrocytic glioma 34 | 2,241
group 3 medulloblastoma 34 | 2,254
Rheumatoid Arthritis 33 | 1,160
group 4 medulloblastoma 33 | 1,875
Mammary Neoplasms 32 | 410
Pick disease 32 | 1,893
ductal carcinoma in situ 31 | 1,745
medulloblastoma 31 | 1,524
adult high grade glioma 30 | 2,148
Leukemia, Myelocytic, Acute 29 | 113
Multiple myeloma 29 | 1,327
acute quadriplegic myopathy 29 | 1,157
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,795
cutaneous lupus erythematosus 28 | 1,056
juvenile dermatomyositis 28 | 1,189
cystic fibrosis 26 | 1,665
primary pancreatic ductal adenocarcinoma 26 | 1,271
primary Sjogren syndrome 25 | 789
Leukemia 24 | 88
Waldenstrons macroglobulinemia 24 | 765
posterior fossa group A ependymoma 24 | 1,511
spina bifida 24 | 1,064
Atopic dermatitis 22 | 944
dermatomyositis 22 | 933
diabetes mellitus 22 | 1,663
sonic hedgehog group medulloblastoma 21 | 1,482
Prostatic Neoplasms 20 | 471
atypical teratoid/rhabdoid tumor 20 | 1,095
posterior fossa group B ependymoma 20 | 1,530
Renal Cell Carcinoma 19 | 199
acute myeloid leukemia 19 | 780
aldosterone-producing adenoma 19 | 664
gastric carcinoma 19 | 832
Stomach Neoplasms 17 | 282
Down syndrome 16 | 548
IGA Glomerulonephritis 16 | 454
Lung Neoplasms 16 | 171
Papillary thyroid carcinoma 16 | 37
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 499
nasopharyngeal carcinoma 16 | 1,056
non-small cell lung carcinoma 16 | 413
Adenoma 15 | 165
Liver carcinoma 15 | 217
active Crohn's disease 15 | 918
Schizophrenia 14 | 501
esophageal adenocarcinoma 14 | 737
gastric cancer 14 | 430
Alzheimer's disease 13 | 644
Chronic Lymphocytic Leukemia 13 | 242
Obesity 13 | 616
mucosa-associated lymphoid tissue lymphoma 13 | 480
non primary Sjogren syndrome sicca 13 | 840
LEUKEMIA, ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, 3 12 | 20
Sarcoma 12 | 49
chronic rhinosinusitis 12 | 512
pancreatic carcinoma 12 | 567
tuberculosis and treatment for 6 months 12 | 686
Adenocarcinoma 11 | 115
Amyotrophic Lateral Sclerosis 11 | 431
Cleft palate 11 | 125
Immune system cancer 11 | 38
Intellectual disability 11 | 573
Kidney disease 11 | 396
Melanoma 11 | 261
Neuroblastoma 11 | 78
hepatocellular carcinoma 11 | 532
progressive supranuclear palsy 11 | 674

Tissue

Endocrine System 229 | 18,512
Nervous System 229 | 18,561
Female tissues 228 | 18,647
Digestive Tract 227 | 18,473
Skin and soft tissues 227 | 18,115
Blood and immune system 226 | 17,995
Liver and Pancreas 226 | 18,136
Male tissues 225 | 17,969
Urinary Tract 225 | 18,444
Cardiovascular System 224 | 17,958
Respiratory system 218 | 17,484

Target Family

Non-IDG 102 | 11,971
Transcription Factor 53 | 1,400
Kinase 41 | 634
Enzyme 24 | 4,146
Epigenetic 7 | 242
Nuclear Receptor 3 | 48
TF/Epigenetic 2 | 38
GPCR 1 | 406

UniProt Keyword

Proto-oncogene 233 | 233
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.21092 1667.7 216
Fibroblast growth factor 5 FGF5 Tbio Non-IDG -2.00731 99.9 143
Transcription factor E2-alpha TCF3 Tbio Transcription Factor -2.76637 577.9 373
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
Tether containing UBX domain for GLUT4 ASPSCR1 Tbio Non-IDG -3.18322 1605.1 195
Myelodysplastic syndrome 2 translocation-associated protein MDS2 Tdark Non-IDG -1.61805 45.7 1
Guanine nucleotide exchange factor DBS MCF2L Tbio Non-IDG -0.93602 11.4 104