Development Level

Tbio 52 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal femur morphology 1 | 14
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal tail morphology 1 | 25
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
cataract 1 | 92
decreased circulating bilirubi... 1 | 19
decreased circulating serum al... 1 | 82
decreased exploration in new e... 1 | 11
decreased food intake 1 | 13
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
mydriasis 1 | 6
pale yolk sac 1 | 25
premature death 1 | 5
short tibia 1 | 97
small adrenal glands 1 | 16
small kidney 1 | 16

Disease

Carcinoma 44 | 11,493
ovarian cancer 36 | 8,520
glioblastoma 31 | 5,792
psoriasis 31 | 6,694
lung cancer 26 | 4,740
Breast cancer 25 | 3,578
atypical teratoid / rhabdoid tumor 25 | 5,112
ependymoma 25 | 4,679
Astrocytoma, Pilocytic 24 | 3,081
lung carcinoma 22 | 2,843
medulloblastoma, large-cell 22 | 6,241
adult high grade glioma 21 | 3,801
invasive ductal carcinoma 21 | 2,951
osteosarcoma 21 | 7,950
pituitary cancer 21 | 1,972
Cancer 19 | 2,499
malignant mesothelioma 19 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
interstitial cystitis 17 | 2,312
Kidney cancer 16 | 2,613
cystic fibrosis 16 | 1,696
non-small cell lung cancer 16 | 2,890
oligodendroglioma 16 | 2,850
pancreatic cancer 16 | 2,398
lung adenocarcinoma 15 | 2,716
primitive neuroectodermal tumor 15 | 3,035
adrenocortical carcinoma 14 | 1,428
ductal carcinoma in situ 14 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
astrocytic glioma 12 | 2,597
breast carcinoma 12 | 1,638
group 3 medulloblastoma 12 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
ulcerative colitis 12 | 1,819
cutaneous lupus erythematosus 11 | 1,057
juvenile dermatomyositis 11 | 1,187
Down syndrome 10 | 499
Duchenne muscular dystrophy 10 | 601
subependymal giant cell astrocytoma 10 | 2,287
Pick disease 9 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
diabetes mellitus 9 | 1,728
esophageal adenocarcinoma 9 | 737
group 4 medulloblastoma 9 | 1,855
medulloblastoma 9 | 720
primary pancreatic ductal adenocarcinoma 9 | 1,109
Myopia 8 | 176
Rheumatoid arthritis 8 | 1,191
Schizophrenia 8 | 1,160
gastric carcinoma 8 | 807
sonic hedgehog group medulloblastoma 8 | 467
Atopic dermatitis 7 | 952
Autosomal recessive predisposition 7 | 1,442
Liver Cirrhosis, Experimental 7 | 769
Liver cancer 7 | 604
Melanoma 7 | 711
colon cancer 7 | 1,478
dermatomyositis 7 | 966
limb girdle muscular dystrophy 2A 7 | 213
tuberculosis 7 | 2,010
Arthritis 6 | 290
Atherosclerosis 6 | 291
Kidney disease 6 | 430
Osteoarthritis 6 | 184
acute quadriplegic myopathy 6 | 1,158
aldosterone-producing adenoma 6 | 665
nasopharyngeal carcinoma 6 | 1,058
pediatric high grade glioma 6 | 1,064
primary Sjogren syndrome 6 | 735
Bipolar Disorder 5 | 666
Degenerative disc disease 5 | 35
Ehlers-Danlos syndrome 5 | 43
Polycystic ovary syndrome 5 | 360
Simpson-Golabi-Behmel syndrome 5 | 19
Skin cancer 5 | 469
Umbilical hernia 5 | 93
astrocytoma 5 | 1,146
fascioscapulohumeral muscular dystrophy 5 | 100
nephrosclerosis 5 | 333
Adenoma 4 | 167
Atrial Septal Defects 4 | 85
Broad flat nasal bridge 4 | 236
Cleft Palate 4 | 271
Cryptorchidism 4 | 296
Hypersensitivity reaction type II disease 4 | 253
Intellectual disability 4 | 1,016
Muscle hypotonia 4 | 571
Nasal bridge wide 4 | 236
Osteoporosis 4 | 363
Platyspondyly 4 | 56
Short hands 4 | 50
Short neck 4 | 140
Short stature 4 | 531
Uranostaphyloschisis 4 | 167
active ulcerative colitis 4 | 764
hereditary spastic paraplegia 4 | 318
non-small cell lung carcinoma 4 | 317
spina bifida 4 | 1,074
urothelial carcinoma 4 | 318

Tissue

Endocrine System 54 | 18,159
Urinary Tract 53 | 16,678
Blood and immune system 52 | 16,909
Female tissues 52 | 17,400
Liver and Pancreas 52 | 16,750
Male tissues 52 | 17,142
Nervous System 52 | 16,725
Skin and soft tissues 52 | 17,230
Digestive Tract 51 | 17,369
Respiratory system 51 | 16,393
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 52 | 12,091
Enzyme 3 | 4,145
GPCR 1 | 408

UniProt Keyword

Proteoglycan 56 | 56
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
MICOS complex subunit MIC26 APOO Tbio Non-IDG -1.25338 18.9 141
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38
Epiphycan EPYC Tbio Non-IDG -1.62043 40.7 82
Protein AMBP AMBP Tbio Non-IDG -2.61031 420.1 396
Testican-1 SPOCK1 Tbio Non-IDG -1.99465 104.6 92
Syndecan-3 SDC3 Tbio Non-IDG -1.86172 78.8 179
Versican core protein VCAN Tbio Non-IDG -2.88501 795.4 190
Inter-alpha-trypsin inhibitor heavy chain H3 ITIH3 Tbio Non-IDG -1.14795 14.5 38