Development Level

Tbio 82 | 10,625
Tchem 38 | 1,890
Tdark 14 | 7,003

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal bone structure 4 | 131
preweaning lethality, incomple... 4 | 260
abnormal embryo size 3 | 112
abnormal sleep behavior 3 | 63
decreased body weight 3 | 174
decreased total body fat amoun... 3 | 186
abnormal behavior 2 | 226
abnormal coat/hair pigmentatio... 2 | 54
decreased body length 2 | 108
decreased circulating glucose ... 2 | 121
decreased circulating magnesiu... 2 | 11
decreased circulating triglyce... 2 | 83
decreased fasted circulating g... 2 | 49
decreased lean body mass 2 | 195
decreased lumbar vertebrae num... 2 | 62
decreased rib number 2 | 59
decreased thoracic vertebrae n... 2 | 7
embryonic lethality prior to o... 2 | 148
hydrops fetalis 2 | 22
impaired glucose tolerance 2 | 52
increased lean body mass 2 | 107
increased or absent threshold ... 2 | 128
increased total body fat amoun... 2 | 57
limb grasping 2 | 35
abnormal QRS complex 1 | 25
abnormal coat appearance 1 | 25
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal humerus morphology 1 | 11
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal posture 1 | 5
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating potassiu... 1 | 17
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased grip strength 1 | 123
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased threshold for audito... 1 | 32
dilated heart left ventricle 1 | 10
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
female infertility 1 | 34
hyperactivity 1 | 108
hypoactivity 1 | 89
increased bone mineral content 1 | 92
increased caudal vertebrae num... 1 | 8
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 93
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
increased vertical activity 1 | 18
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
small adrenal glands 1 | 15
small testis 1 | 37
vertebral fusion 1 | 23

Disease

osteosarcoma 73 | 7,933
ovarian cancer 73 | 8,484
medulloblastoma, large-cell 60 | 6,234
glioblastoma 57 | 5,572
psoriasis 46 | 6,685
atypical teratoid / rhabdoid tumor 45 | 4,369
lung cancer 45 | 4,466
malignant mesothelioma 36 | 3,162
Breast cancer 31 | 3,094
pediatric high grade glioma 30 | 2,712
lung adenocarcinoma 28 | 2,713
non-small cell lung cancer 28 | 2,798
ulcerative colitis 28 | 2,087
Pick disease 27 | 1,893
interstitial cystitis 27 | 2,299
invasive ductal carcinoma 27 | 2,950
ependymoma 26 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,289
oligodendroglioma 26 | 2,849
pilocytic astrocytoma 26 | 3,086
primitive neuroectodermal tumor 26 | 3,031
astrocytic glioma 25 | 2,241
group 3 medulloblastoma 25 | 2,254
adult high grade glioma 24 | 2,148
group 4 medulloblastoma 24 | 1,875
subependymal giant cell astrocytoma 24 | 2,287
Cancer 22 | 2,346
colon cancer 21 | 1,475
Carcinoma 20 | 2,147
lung carcinoma 20 | 2,844
pituitary cancer 20 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
medulloblastoma 18 | 1,524
pancreatic cancer 17 | 2,300
tuberculosis 17 | 1,557
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
breast carcinoma 15 | 1,614
spina bifida 15 | 1,064
posterior fossa group A ependymoma 14 | 1,511
Multiple myeloma 13 | 1,327
acute quadriplegic myopathy 13 | 1,157
cystic fibrosis 13 | 1,665
ductal carcinoma in situ 13 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
posterior fossa group B ependymoma 13 | 1,530
Rheumatoid Arthritis 12 | 1,160
adrenocortical carcinoma 12 | 1,427
juvenile dermatomyositis 12 | 1,189
astrocytoma 11 | 1,493
esophageal adenocarcinoma 11 | 737
Waldenstrons macroglobulinemia 10 | 765
cutaneous lupus erythematosus 10 | 1,056
diabetes mellitus 10 | 1,663
gastric carcinoma 10 | 832
active Crohn's disease 9 | 918
dermatomyositis 9 | 933
progressive supranuclear palsy 9 | 674
Duchenne muscular dystrophy 8 | 602
IGA Glomerulonephritis 8 | 454
aldosterone-producing adenoma 8 | 664
non primary Sjogren syndrome sicca 8 | 840
primary pancreatic ductal adenocarcinoma 8 | 1,271
sonic hedgehog group medulloblastoma 8 | 1,482
tuberculosis and treatment for 6 months 8 | 686
Crohn's disease 7 | 304
Endometriosis 7 | 535
acute myeloid leukemia 7 | 780
atypical teratoid/rhabdoid tumor 7 | 1,095
hereditary spastic paraplegia 7 | 313
urothelial carcinoma 7 | 318
Alzheimer's disease 6 | 644
Down syndrome 6 | 548
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
hepatocellular carcinoma 6 | 532
nasopharyngeal carcinoma 6 | 1,056
pancreatic carcinoma 6 | 567
Atopic dermatitis 5 | 944
Chronic Lymphocytic Leukemia 5 | 242
Melanoma 5 | 261
Myocardial Ischemia 5 | 169
Parkinson's disease 5 | 364
Peripheral Neuropathy 5 | 303
active ulcerative colitis 5 | 477
chronic rhinosinusitis 5 | 512
fibroadenoma 5 | 557
gastric cancer 5 | 430
inflammatory breast cancer 5 | 404
primary Sjogren syndrome 5 | 789
Acquired metabolic disease 4 | 267
Amyotrophic Lateral Sclerosis 4 | 431
Asthma 4 | 349
Barrett's esophagus 4 | 183
Colorectal Neoplasms 4 | 217
Nonsyndromic deafness 4 | 121
Schizophrenia 4 | 501
Vascular disease 4 | 281
chronic lymphosyte leukemia 4 | 232
tuberculosis and treatment for 3 months 4 | 327
Prostatic Neoplasms 3 | 471
nephrosclerosis 3 | 329

Tissue

Blood and immune system 131 | 17,995
Nervous System 131 | 18,561
Urinary Tract 131 | 18,444
Cardiovascular System 130 | 17,958
Digestive Tract 130 | 18,473
Endocrine System 130 | 18,512
Liver and Pancreas 130 | 18,136
Male tissues 130 | 17,969
Female tissues 129 | 18,647
Skin and soft tissues 129 | 18,115
Respiratory system 128 | 17,484

Target Family

Enzyme 129 | 4,146
Non-IDG 5 | 11,971

UniProt Keyword

Protein phosphatase 134 | 134
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein phosphatase non-receptor type 13 PTPN13 Tchem Enzyme -2.20613 177.9 120
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.94494 110.6 235
Dual specificity protein phosphatase 18 DUSP18 Tbio Enzyme -0.67210 5.47 19
Protein phosphatase Slingshot homolog 1 SSH1 Tbio Enzyme -1.41770 25.0 106
Dual specificity protein phosphatase 23 DUSP23 Tbio Enzyme -0.95604 11.5 79
Protein phosphatase PTC7 homolog PPTC7 Tdark Enzyme 0.85 0.09 72
Protein phosphatase Slingshot homolog 2 SSH2 Tchem Enzyme -0.70039 3.84 25
Low molecular weight phosphotyrosine protein phosphatase ACP1 Tchem Enzyme -2.42254 282.0 209
Protein phosphatase 1D PPM1D Tchem Enzyme -2.07873 162.2 195
PH domain leucine-rich repeat-containing protein phosphatase 2 PHLPP2 Tbio Enzyme -1.27425 16.1 120