Development Level

Tbio 13 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
preweaning lethality, incomple... 2 | 499
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal outer ear morphology 1 | 3
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
decreased circulating insulin ... 1 | 76
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
increased startle reflex 1 | 112
microphthalmia 1 | 26
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

ovarian cancer 11 | 8,520
psoriasis 11 | 6,694
medulloblastoma, large-cell 10 | 6,241
glioblastoma 9 | 5,792
osteosarcoma 9 | 7,950
lung cancer 8 | 4,740
malignant mesothelioma 7 | 3,232
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
Astrocytoma, Pilocytic 5 | 3,081
Carcinoma 5 | 11,493
adrenocortical carcinoma 5 | 1,428
astrocytic glioma 5 | 2,597
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
non-small cell lung cancer 5 | 2,890
Breast cancer 4 | 3,578
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
non primary Sjogren syndrome sicca 4 | 891
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
primary pancreatic ductal adenocarcinoma 4 | 1,109
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Cancer 3 | 2,499
Hypercalcemia 3 | 59
Lung Neoplasms 3 | 232
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
fibroadenoma 3 | 559
head and neck cancer 3 | 271
tuberculosis 3 | 2,010
Abdominal pain, episodic 2 | 9
Acromegaly 2 | 51
Adenoma 2 | 167
Adrenal cortical adenoma 2 | 19
Angiofibroma 2 | 7
Chronic Lymphocytic Leukemia 2 | 262
Diarrhea 2 | 253
Esophagitis 2 | 35
Growth hormone excess 2 | 14
Heart disease 2 | 306
Hyperinsulinaemic hypoglycaemia 2 | 16
Hyperinsulinemia, fasting 2 | 7
Hyperparathyroidism 2 | 48
Increased serum parathyroid hormone 2 | 14
Insulinoma 2 | 24
Intestinal Neoplasms 2 | 12
Kidney Diseases 2 | 114
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Multiple Endocrine Neoplasia Type 1 2 | 29
Multiple myeloma 2 | 1,332
Non-Functioning Pituitary Gland Neoplasm 2 | 6
Parathyroid Adenoma 2 | 19
Parathyroid hyperplasia 2 | 6
Peptic Ulcer 2 | 27
Pituitary growth hormone cell adenoma 2 | 8
Prolactinoma 2 | 11
Prostatic Neoplasms 2 | 495
Stomach Neoplasms 2 | 300
Subcutaneous lipomas 2 | 9
Thyroid Gland Follicular Adenoma 2 | 9
Zollinger-Ellison syndrome 2 | 18
acute quadriplegic myopathy 2 | 1,158
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,478
gastric cancer 2 | 459
group 4 medulloblastoma 2 | 1,855
intermittent abdominal pain 2 | 9
interstitial lung disease 2 | 298
lung carcinoma 2 | 2,843
nephrosclerosis 2 | 333
non diabetic and post-ischemic heart failure 2 | 200
Barrett's esophagus 1 | 182
Cardiomegaly 1 | 116
Esophageal Squamous Cell Carcinoma 1 | 77
HIV Infections 1 | 102
Kidney Neoplasm 1 | 29
Kidney Neoplasms 1 | 37
Neonatal hypoglycemia 1 | 17
Pseudohypoaldosteronism 1 | 23
Squamous cell carcinoma of esophagus 1 | 77
inflammatory breast cancer 1 | 286

Tissue

Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Urinary Tract 13 | 16,678

Target Family

Enzyme 8 | 4,145
Kinase 4 | 634
Non-IDG 2 | 12,091

UniProt Keyword

Protein kinase inhibitor 14 | 14
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.63966 41.9 162
Calcium/calmodulin-dependent protein kinase II inhibitor 2 CAMK2N2 Tbio Enzyme -1.13578 13.4 52
Cyclin-dependent kinase inhibitor 1C CDKN1C Tbio Enzyme -2.81199 631.0 665
Serine/threonine-protein kinase WNK1 WNK1 Tchem Kinase -2.79557 617.6 414
Calcineurin B homologous protein 3 TESC Tbio Non-IDG -1.17248 18.3 110
cAMP-dependent protein kinase inhibitor alpha PKIA Tbio Enzyme -1.27058 17.1 34
Calcium/calmodulin-dependent protein kinase II inhibitor 1 CAMK2N1 Tbio Enzyme -0.51423 3.98 64
cAMP-dependent protein kinase inhibitor beta PKIB Tbio Enzyme -0.86549 8.17 63
Tribbles homolog 1 TRIB1 Tbio Kinase -1.74370 59.4 250
Tribbles homolog 3 TRIB3 Tbio Kinase -1.93599 97.7 421