Development Level

Tbio 42 | 11,445
Tclin 5 | 613
Tchem 3 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal behavioral response t... 1 | 66
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased fluid intake 1 | 3
decreased food intake 1 | 13
decreased respiratory quotient 1 | 16
decreased vertical activity 1 | 208
increased circulating choleste... 1 | 66
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

ovarian cancer 42 | 8,520
Multiple myeloma 28 | 1,332
lung cancer 26 | 4,740
Carcinoma 25 | 11,493
psoriasis 25 | 6,694
osteosarcoma 24 | 7,950
glioblastoma 18 | 5,792
HIV Infections 15 | 102
dermatomyositis 12 | 966
Waldenstrons macroglobulinemia 11 | 765
ependymoma 10 | 4,679
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Breast cancer 9 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
Cancer 8 | 2,499
adult high grade glioma 8 | 3,801
atypical teratoid / rhabdoid tumor 8 | 5,112
malignant mesothelioma 8 | 3,232
medulloblastoma, large-cell 8 | 6,241
non-small cell lung cancer 8 | 2,890
diabetes mellitus 7 | 1,728
group 3 medulloblastoma 7 | 4,104
astrocytic glioma 6 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
oligodendroglioma 6 | 2,850
subependymal giant cell astrocytoma 6 | 2,287
Mantle cell lymphoma 5 | 23
astrocytoma 5 | 1,146
non primary Sjogren syndrome sicca 5 | 891
primary Sjogren syndrome 5 | 735
Astrocytoma, Pilocytic 4 | 3,081
Kidney cancer 4 | 2,613
Liver Cirrhosis, Experimental 4 | 769
Pick disease 4 | 1,894
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung adenocarcinoma 4 | 2,716
tuberculosis 4 | 2,010
Osteoporosis 3 | 363
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
Acquired metabolic disease 2 | 336
Alzheimer's disease 2 | 658
Animal Mammary Neoplasms 2 | 136
Attention deficit hyperactivity disorder 2 | 278
Cockayne syndrome 2 | 60
Congestive heart failure 2 | 113
Craniofacial Abnormalities 2 | 151
Duchenne muscular dystrophy 2 | 601
Esophageal Squamous Cell Carcinoma 2 | 77
Intellectual disability 2 | 1,016
Macroglossia 2 | 65
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Photosensitive trichothiodystrophy 2 | 30
Prostate cancer 2 | 175
Squamous cell carcinoma of esophagus 2 | 77
Vascular disease 2 | 319
Xeroderma pigmentosum 2 | 43
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
chronic kidney disease 2 | 90
cutaneous lupus erythematosus 2 | 1,057
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
inflammatory breast cancer 2 | 286
interstitial cystitis 2 | 2,312
pituitary cancer 2 | 1,972
substance-related disorder 2 | 162
Amenorrhea 1 | 58
Carcinoma, Squamous Cell 1 | 110
Cervical cancer 1 | 24
Cocaine Dependence 1 | 51
Conjunctivitis 1 | 53
Drooling 1 | 27
Erythema 1 | 58
Exanthema 1 | 43
Exotropia 1 | 35
Fatty Liver 1 | 70
Flushing 1 | 60
Full lower lip 1 | 64
Hepatitis A 1 | 11
Hereditary renal cell carcinoma 1 | 3
Hypertriglyceridemia result 1 | 37
JMP syndrome 1 | 2
Obsessive compulsive behavior 1 | 25
Peripheral Neuropathy 1 | 134
Pitt-Hopkins syndrome 1 | 20
Progressive mental retardation 1 | 37
Prominent lower lip 1 | 64
Protrusion of tongue 1 | 11
Sialorrhea 1 | 28
Syndactyly of fingers 1 | 48
Waterhouse-Friderichsen syndrome 1 | 11
obsessive-compulsive disorder 1 | 61

Tissue

Endocrine System 53 | 18,159
Blood and immune system 52 | 16,909
Digestive Tract 52 | 17,369
Female tissues 52 | 17,400
Male tissues 52 | 17,142
Nervous System 52 | 16,725
Respiratory system 52 | 16,393
Urinary Tract 52 | 16,678
Cardiovascular System 51 | 15,192
Liver and Pancreas 51 | 16,750
Skin and soft tissues 51 | 17,230

Target Family

Enzyme 41 | 4,145
Non-IDG 12 | 12,091

UniProt Keyword

Proteasome 53 | 53
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
Proteasomal ATPase-associated factor 1 PAAF1 Tbio Enzyme -1.66158 45.6 80
Ubiquilin-1 UBQLN1 Tbio Non-IDG -1.92650 87.0 256
Thioredoxin-like protein 1 TXNL1 Tbio Non-IDG -2.32888 224.7 143
Proteasome subunit alpha type-7 PSMA7 Tbio Enzyme -2.71627 496.7 288
26S proteasome non-ATPase regulatory subunit 11 PSMD11 Tbio Enzyme -1.13234 13.3 211
Proteasome subunit alpha type-6 PSMA6 Tbio Enzyme -2.80973 614.4 288
Proteasome subunit alpha type-2 PSMA2 Tbio Enzyme -0.82346 5.78 245