Development Level

Tbio 3 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased bone mineral density 1 | 72
increased lymphocyte cell numb... 1 | 32
thrombocytopenia 1 | 56

Disease

Carcinoma 5 | 11,493
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Breast cancer 2 | 3,578
Multiple myeloma 2 | 1,332
acute quadriplegic myopathy 2 | 1,158
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
psoriasis 2 | 6,694
Astrocytoma, Pilocytic 1 | 3,081
Corneal Dystrophy, Crystalline, of Schnyder 1 | 1
Corneal dystrophy 1 | 24
Cystinosis 1 | 14
Down syndrome 1 | 499
Edema, Cardiac 1 | 3
Familial partial lipodystrophy 1 | 12
Hermansky-Pudlak syndrome 1 | 42
Intracranial Hemorrhages 1 | 16
Lung Neoplasms 1 | 232
Pontocerebellar hypoplasia 1 | 36
Rift Valley fever 1 | 14
Schnyder Corneal Dystrophy 1 | 23
Schnyder crystalline corneal dystrophy 1 | 1
Waldenstrons macroglobulinemia 1 | 765
acute myeloid leukemia 1 | 783
adrenocortical carcinoma 1 | 1,428
adult high grade glioma 1 | 3,801
astrocytoma 1 | 1,146
colon cancer 1 | 1,478
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,728
esophageal adenocarcinoma 1 | 737
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
oligodendroglioma 1 | 2,850
pituitary cancer 1 | 1,972
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 7 | 4,145

UniProt Keyword

Prenyltransferase 7 | 7
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

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