Development Level

Tbio 13 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

female infertility 2 | 60
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart left ventricle ... 1 | 16
abnormal seminal vesicle morph... 1 | 114
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating iron lev... 1 | 32
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
improved glucose tolerance 1 | 79
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Premature ovarian failure 14 | 65
Carcinoma 11 | 11,493
Premature Menopause 8 | 31
Infertility 7 | 188
Amenorrhea 5 | 58
Elevated gonadotropins 5 | 15
Kidney cancer 5 | 2,613
ovarian cancer 5 | 8,520
Male infertility 4 | 206
Ovarian dysfunction 4 | 18
adult high grade glioma 4 | 3,801
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Delayed bone age 3 | 136
Gonadal Dysgenesis 3 | 28
Hypogonadism 3 | 173
Ovarian Failure, Premature 3 | 9
Primary physiologic amenorrhea 3 | 55
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
non-small cell lung cancer 3 | 2,890
46 XX gonadal dysgenesis 2 | 5
Aplasia/Hypoplasia of the breasts 2 | 10
Aplasia/hypoplasia of the uterus 2 | 4
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Cryptorchidism 2 | 296
Decreased fertility 2 | 33
Delayed Puberty 2 | 97
Generalized osteopenia 2 | 99
Gonadal Dysgenesis, 46,XX 2 | 5
Gonadal Dysgenesis, Mixed 2 | 19
Gynecomastia 2 | 64
Intellectual disability 2 | 1,016
Low serum estradiol levels 2 | 22
Male infertility with azoospermia or oligozoospermia due to single gene mutation 2 | 9
Nystagmus 2 | 317
Osteopenia 2 | 99
Osteoporosis of vertebrae 2 | 5
Polycystic ovary syndrome 2 | 360
Primary Ovarian Insufficiency 2 | 6
Primary hypogonadism 2 | 37
Pure Gonadal Dysgenesis, 46, XX 2 | 5
Pure gonadal dysgenesis 2 | 19
Sertoli-Leydig cell tumor 2 | 5
Small testicle 2 | 75
Sparse pubic hair 2 | 31
Streak ovary 2 | 15
blepharophimosis, ptosis, and epicanthus inversus syndrome 2 | 8
cystic fibrosis 2 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
46,XY partial gonadal dysgenesis 1 | 9
Abnormal sex determination 1 | 11
Abnormality of the labia 1 | 9
Abnormality of the scrotum 1 | 9
Androgen insensitivity syndrome 1 | 12
Atypical autism 1 | 26
Childhood Ataxia with Central Nervous System Hypomyelinization 1 | 6
Decreased fertility in females 1 | 20
Depressive Symptoms 1 | 28
Dysesthesia 1 | 6
Elevated follicle stimulating hormone 1 | 15
Elevated luteinizing hormone 1 | 14
Female external genitalia in males 1 | 13
High pitched voice 1 | 23
Hypertrophic cardiomyopathy 20 1 | 12
Hypoplasia of vagina 1 | 14
Macroorchidism 1 | 7
Mixed anxiety and depressive disorder 1 | 12
Myalgia 1 | 54
OVARIOLEUKODYSTROPHY 1 | 6
Oophoritis 1 | 10
Ossifying fibroma 1 | 15
PREMATURE OVARIAN FAILURE 10 1 | 1
Periarthritis 1 | 6
Photosensitive trichothiodystrophy 1 | 30
Premature Ovarian Failure 8 1 | 2
Rudimentary vagina 1 | 14
Sex reversal 1 | 10
Spastic hemiplegia 1 | 7
Streaky metaphyseal sclerosis 1 | 2
Terminal tremor 1 | 20
Testicular regression syndrome 1 | 9
UV-sensitive syndrome 1 | 10
Urogenital sinus anomaly 1 | 15
X-linked adrenal hypoplasia congenita 1 | 11
menstrual periods stopped for over 6 months 1 | 13

Tissue

Endocrine System 14 | 18,159
Female tissues 13 | 17,400
Skin and soft tissues 12 | 17,230
Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Male tissues 11 | 17,142
Respiratory system 11 | 16,393
Nervous System 10 | 16,725
Liver and Pancreas 9 | 16,750
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 7 | 12,091
Enzyme 3 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

UniProt Keyword

Premature ovarian failure 15 | 15
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cohesin subunit SA-3 STAG3 Tbio Non-IDG -1.30055 20.0 104
Factor in the germline alpha FIGLA Tbio Transcription Factor -1.53789 36.4 71
Alanine--tRNA ligase, mitochondrial AARS2 Tbio Enzyme -1.57311 34.3 75
Probable ATP-dependent DNA helicase HFM1 HFM1 Tbio Enzyme -1.67709 47.0 59
Chimeric ERCC6-PGBD3 protein ERCC6 Tbio Non-IDG -2.31776 361.5 0
Steroidogenic factor 1 NR5A1 Tchem Nuclear Receptor -2.91071 877.0 279
Homeobox protein NOBOX NOBOX Tbio Transcription Factor -1.72297 50.9 87
Protein diaphanous homolog 2 DIAPH2 Tbio Non-IDG -1.70372 49.0 172
DNA helicase MCM8 MCM8 Tbio Enzyme -1.42239 28.6 195
Protein POF1B POF1B Tbio Non-IDG -0.76627 6.14 74