Development Level

Tclin 63 | 602
Tbio 35 | 10,625
Tchem 13 | 1,890
Tdark 5 | 7,003

Collection

Eligible Ion Channel Proteins 29 | 117

IMPC Term

abnormal behavior 4 | 226
hyperactivity 3 | 108
abnormal epididymis morphology 2 | 31
abnormal retinal pigmentation 2 | 61
decreased body weight 2 | 174
decreased fasted circulating g... 2 | 49
decreased lean body mass 2 | 195
enlarged epididymis 2 | 27
impaired glucose tolerance 2 | 52
increased circulating HDL chol... 2 | 63
increased circulating magnesiu... 2 | 10
increased mean corpuscular vol... 2 | 91
preweaning lethality, complete... 2 | 633
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal gait 1 | 51
abnormal iris transilluminatio... 1 | 1
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased B cell number 1 | 30
decreased NK T cell number 1 | 28
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased erythrocyte cell num... 1 | 43
decreased gamma-delta T cell n... 1 | 18
decreased hemoglobin content 1 | 53
decreased mature B cell number 1 | 25
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
enlarged thymus 1 | 4
increased CD4-positive, CD25-p... 1 | 18
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased caudal vertebrae num... 1 | 8
increased circulating alkaline... 1 | 119
increased circulating amylase ... 1 | 13
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased vertical activity 1 | 18
kyphosis 1 | 5
limb grasping 1 | 35
preweaning lethality, incomple... 1 | 260
tremors 1 | 34
trunk curl 1 | 15

Disease

medulloblastoma, large-cell 57 | 6,234
glioblastoma 50 | 5,572
Multiple Sclerosis 43 | 498
pilocytic astrocytoma 41 | 3,086
Eaton-Lambert syndrome 40 | 40
primitive neuroectodermal tumor 39 | 3,031
atypical teratoid / rhabdoid tumor 38 | 4,369
oligodendroglioma 36 | 2,849
psoriasis 35 | 6,685
ependymoma 34 | 2,514
osteosarcoma 34 | 7,933
ovarian cancer 34 | 8,484
Carcinoma 32 | 2,147
pediatric high grade glioma 29 | 2,712
astrocytic glioma 27 | 2,241
subependymal giant cell astrocytoma 27 | 2,287
Atrial Fibrillation 25 | 110
Epilepsy 23 | 346
lung cancer 23 | 4,466
lung carcinoma 23 | 2,844
medulloblastoma 23 | 1,524
Long QT syndrome 22 | 52
adult high grade glioma 22 | 2,148
malignant mesothelioma 22 | 3,162
pituitary cancer 22 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
posterior fossa group A ependymoma 17 | 1,511
Breast cancer 16 | 3,094
Pick disease 16 | 1,893
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
atypical teratoid/rhabdoid tumor 15 | 1,095
sonic hedgehog group medulloblastoma 15 | 1,482
cystic fibrosis 14 | 1,665
lung adenocarcinoma 14 | 2,713
ductal carcinoma in situ 13 | 1,745
group 3 medulloblastoma 13 | 2,254
interstitial cystitis 12 | 2,299
invasive ductal carcinoma 12 | 2,950
Chronic heart failure 11 | 46
group 4 medulloblastoma 11 | 1,875
non-small cell lung cancer 11 | 2,798
pancreatic cancer 11 | 2,300
adrenocortical carcinoma 10 | 1,427
Episodic ataxia 9 | 17
Intellectual disability 9 | 573
Schnyder corneal dystrophy 9 | 23
active Crohn's disease 9 | 918
astrocytoma 9 | 1,493
posterior fossa group B ependymoma 9 | 1,530
Congestive heart failure 8 | 30
Poisoning by digitalis glycoside 8 | 8
active ulcerative colitis 8 | 477
colon cancer 8 | 1,475
Heart disease 7 | 279
Hyperaldosteronism 7 | 27
Hypertension 7 | 287
Hypokalemia 7 | 40
breast carcinoma 7 | 1,614
diabetes mellitus 7 | 1,663
gastric carcinoma 7 | 832
primary pancreatic ductal adenocarcinoma 7 | 1,271
progressive supranuclear palsy 7 | 674
ulcerative colitis 7 | 2,087
Brugada syndrome 6 | 26
Down syndrome 6 | 548
Parkinson's disease 6 | 364
cutaneous lupus erythematosus 6 | 1,056
Alzheimer's disease 5 | 644
Cancer 5 | 2,346
Congenital long QT syndrome 5 | 8
Conn's syndrome 5 | 22
General anesthesia 5 | 53
Heart conduction disease 5 | 65
Hypertensive disease 5 | 193
Osteoporosis 5 | 257
Romano-Ward Syndrome 5 | 12
Sensorineural hearing loss 5 | 107
Short QT syndrome 5 | 12
Type 2 diabetes mellitus 5 | 189
aldosterone-producing adenoma 5 | 664
fibroadenoma 5 | 557
nasopharyngeal carcinoma 5 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
tuberculosis and treatment for 6 months 5 | 686
Angina pectoris 4 | 21
Brugada Syndrome (disorder) 4 | 15
Diabetes Mellitus, Non-Insulin-Dependent 4 | 157
Duchenne muscular dystrophy 4 | 602
Familial atrial fibrillation 4 | 16
Kidney disease 4 | 396
Migraine 4 | 79
Muscle Weakness 4 | 92
Neurodegenerative disease 4 | 383
Paroxysmal atrial fibrillation 4 | 6
Seizures 4 | 95
chronic rhinosinusitis 4 | 512
glioblastoma multiforme 4 | 347
nephrosclerosis 4 | 329
tuberculosis 4 | 1,557

Tissue

Nervous System 116 | 18,561
Digestive Tract 115 | 18,473
Endocrine System 115 | 18,512
Urinary Tract 115 | 18,444
Female tissues 113 | 18,647
Liver and Pancreas 113 | 18,136
Cardiovascular System 112 | 17,958
Male tissues 112 | 17,969
Skin and soft tissues 112 | 18,115
Blood and immune system 111 | 17,995
Respiratory system 110 | 17,484

Target Family

Ion Channel 92 | 341
Transporter 22 | 473
Enzyme 1 | 4,146
Non-IDG 1 | 11,971

UniProt Keyword

Potassium transport 116 | 116
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Potassium-transporting ATPase subunit beta ATP4B Tclin Transporter -0.76953 6.01 159
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.04732 117.9 108
Potassium voltage-gated channel subfamily A member 3 KCNA3 Tclin Ion Channel -2.64735 493.0 284
Sodium/potassium-transporting ATPase subunit alpha-3 ATP1A3 Tclin Transporter -2.09703 131.9 103
G protein-activated inward rectifier potassium channel 4 KCNJ5 Tchem Ion Channel -2.24687 186.6 114
G protein-activated inward rectifier potassium channel 1 KCNJ3 Tchem Ion Channel -2.31340 205.5 237
Potassium voltage-gated channel subfamily C member 1 KCNC1 Tclin Ion Channel -2.42317 260.8 283
Potassium voltage-gated channel subfamily H member 5 KCNH5 Tclin Ion Channel -1.18796 17.3 34
Voltage-gated potassium channel subunit beta-3 KCNAB3 Tdark Ion Channel -0.68945 4.88 108