Development Level

Tclin 65 | 613
Tbio 47 | 11,445
Tchem 22 | 1,598
Tdark 3 | 6,588

Collection

Ion Channel: IDG Consortium (T... 28 | 99

IMPC Phenotype

abnormal behavior 8 | 298
hyperactivity 6 | 148
preweaning lethality, complete... 6 | 979
impaired glucose tolerance 3 | 75
increased bone mineral content 3 | 108
increased mean corpuscular vol... 3 | 92
abnormal behavioral response t... 2 | 66
abnormal epididymis morphology 2 | 42
decreased body weight 2 | 161
decreased fasted circulating g... 2 | 65
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
decreased vertical activity 2 | 208
enlarged epididymis 2 | 31
increased blood urea nitrogen ... 2 | 48
increased mean platelet volume 2 | 45
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal coat-hair pigmentatio... 1 | 64
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal iris transilluminatio... 1 | 2
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac stroke volum... 1 | 6
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased granulocyte number 1 | 6
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased mean platelet volume 1 | 25
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
enlarged thymus 1 | 5
hydroencephaly 1 | 14
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 22
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased vertical activity 1 | 24
kyphosis 1 | 5
limb grasping 1 | 41
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened QT interval 1 | 4
shortened ST segment 1 | 10
tremors 1 | 39

Disease

Carcinoma 108 | 11,493
medulloblastoma, large-cell 68 | 6,241
ependymoma 62 | 4,679
glioblastoma 60 | 5,792
atypical teratoid / rhabdoid tumor 59 | 5,112
adult high grade glioma 53 | 3,801
group 3 medulloblastoma 47 | 4,104
ovarian cancer 45 | 8,520
Astrocytoma, Pilocytic 44 | 3,081
Multiple Sclerosis 44 | 540
osteosarcoma 43 | 7,950
primitive neuroectodermal tumor 43 | 3,035
psoriasis 42 | 6,694
oligodendroglioma 41 | 2,850
Eaton-Lambert syndrome 40 | 40
Kidney cancer 38 | 2,613
astrocytic glioma 35 | 2,597
Epilepsy 34 | 792
lung cancer 34 | 4,740
subependymal giant cell astrocytoma 29 | 2,287
Atrial Fibrillation 27 | 124
lung carcinoma 27 | 2,843
malignant mesothelioma 26 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
pituitary cancer 23 | 1,972
Breast cancer 22 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
Pick disease 21 | 1,894
Seizures 21 | 596
Intellectual disability 19 | 1,016
pancreatic cancer 19 | 2,398
invasive ductal carcinoma 18 | 2,951
lung adenocarcinoma 18 | 2,716
ductal carcinoma in situ 17 | 1,745
Long QT syndrome 16 | 39
Schizophrenia 16 | 1,160
cystic fibrosis 15 | 1,696
Autosomal recessive predisposition 14 | 1,442
Bipolar Disorder 14 | 666
adrenocortical carcinoma 14 | 1,428
interstitial cystitis 14 | 2,312
non-small cell lung cancer 14 | 2,890
Dull intelligence 13 | 645
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Poor school performance 13 | 645
group 4 medulloblastoma 12 | 1,855
Chronic heart failure 11 | 46
Muscle hypotonia 11 | 571
active ulcerative colitis 11 | 764
colon cancer 11 | 1,478
Cognitive delay 10 | 608
Congestive heart failure 10 | 113
Episodic ataxia 10 | 22
Global developmental delay 10 | 608
Hypertension 10 | 396
Mental and motor retardation 10 | 608
active Crohn's disease 10 | 922
gastric carcinoma 10 | 807
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
progressive supranuclear palsy 10 | 676
Brugada syndrome 9 | 29
Heart disease 9 | 306
Mental Depression 9 | 333
breast carcinoma 9 | 1,638
primary pancreatic ductal adenocarcinoma 9 | 1,109
tuberculosis 9 | 2,010
Cerebellar Ataxia 8 | 304
Hyperaldosteronism 8 | 35
Hypokalemia 8 | 52
Liver cancer 8 | 604
Melanoma 8 | 711
Parkinson's disease 8 | 392
Poisoning by digitalis glycoside 8 | 8
Schnyder Corneal Dystrophy 8 | 23
Skin cancer 8 | 469
astrocytoma 8 | 1,146
cutaneous lupus erythematosus 8 | 1,057
diabetes mellitus 8 | 1,728
ulcerative colitis 8 | 1,819
Birk-Barel syndrome 7 | 8
Cancer 7 | 2,499
Depressive disorder 7 | 409
Neurodegenerative disease 7 | 414
Osteoporosis 7 | 363
Paroxysmal atrial fibrillation 7 | 14
fibroadenoma 7 | 559
Alzheimer's disease 6 | 658
Amyotrophic lateral sclerosis 6 | 451
Down syndrome 6 | 499
Failure to gain weight 6 | 365
Hypertensive disease 6 | 292
Kidney disease 6 | 430
Pediatric failure to thrive 6 | 365
Type 2 diabetes mellitus 6 | 272
Vascular disease 6 | 319
nasopharyngeal carcinoma 6 | 1,058
sonic hedgehog group medulloblastoma 6 | 467

Tissue

Endocrine System 136 | 18,159
Nervous System 129 | 16,725
Digestive Tract 125 | 17,369
Female tissues 125 | 17,400
Male tissues 124 | 17,142
Skin and soft tissues 122 | 17,230
Liver and Pancreas 118 | 16,750
Urinary Tract 117 | 16,678
Blood and immune system 115 | 16,909
Respiratory system 110 | 16,393
Cardiovascular System 98 | 15,192

Target Family

Ion Channel 95 | 344
Transporter 26 | 473
Enzyme 12 | 4,145
Kinase 3 | 634
Non-IDG 1 | 12,091

UniProt Keyword

Potassium 137 | 137
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 HCN2 Tclin Ion Channel -1.16715 13.3 162
Solute carrier family 12 member 7 SLC12A7 Tbio Transporter -1.46102 28.2 156
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Potassium voltage-gated channel subfamily H member 3 KCNH3 Tclin Ion Channel -1.07866 11.8 67
Potassium voltage-gated channel subfamily A member 7 KCNA7 Tclin Ion Channel -0.87978 7.43 59
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.63683 41.4 75
Solute carrier family 12 member 1 SLC12A1 Tclin Transporter -2.37125 226.3 178
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.34610 217.9 162
Potassium voltage-gated channel subfamily E member 4 KCNE4 Tbio Ion Channel -1.17671 15.9 99
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205