Development Level

Tclin 65 | 602
Tbio 44 | 10,625
Tchem 15 | 1,890
Tdark 5 | 7,003

Collection

Eligible Ion Channel Proteins 29 | 117

IMPC Term

abnormal behavior 4 | 226
hyperactivity 3 | 108
preweaning lethality, complete... 3 | 633
abnormal epididymis morphology 2 | 31
abnormal retinal pigmentation 2 | 61
decreased body weight 2 | 174
decreased fasted circulating g... 2 | 49
decreased lean body mass 2 | 195
decreased prepulse inhibition 2 | 52
enlarged epididymis 2 | 27
impaired glucose tolerance 2 | 52
increased circulating HDL chol... 2 | 63
increased circulating magnesiu... 2 | 10
increased mean corpuscular vol... 2 | 91
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal gait 1 | 51
abnormal iris transilluminatio... 1 | 1
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased B cell number 1 | 30
decreased NK T cell number 1 | 28
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased erythrocyte cell num... 1 | 43
decreased gamma-delta T cell n... 1 | 18
decreased hemoglobin content 1 | 53
decreased mature B cell number 1 | 25
decreased rib number 1 | 59
enlarged thymus 1 | 4
immune system phenotype 1 | 17
increased CD4-positive, CD25-p... 1 | 18
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased caudal vertebrae num... 1 | 8
increased circulating alkaline... 1 | 119
increased circulating amylase ... 1 | 13
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased vertical activity 1 | 18
kyphosis 1 | 5
limb grasping 1 | 35
preweaning lethality, incomple... 1 | 260
tremors 1 | 34
trunk curl 1 | 15

Disease

medulloblastoma, large-cell 63 | 6,234
glioblastoma 53 | 5,572
Multiple Sclerosis 43 | 498
atypical teratoid / rhabdoid tumor 41 | 4,369
osteosarcoma 41 | 7,933
pilocytic astrocytoma 41 | 3,086
Eaton-Lambert syndrome 40 | 40
ovarian cancer 40 | 8,484
primitive neuroectodermal tumor 40 | 3,031
psoriasis 40 | 6,685
oligodendroglioma 39 | 2,849
ependymoma 36 | 2,514
Carcinoma 32 | 2,147
astrocytic glioma 30 | 2,241
pediatric high grade glioma 30 | 2,712
subependymal giant cell astrocytoma 27 | 2,287
lung cancer 26 | 4,466
Atrial Fibrillation 25 | 110
lung carcinoma 24 | 2,844
malignant mesothelioma 24 | 3,162
medulloblastoma 24 | 1,524
Epilepsy 23 | 346
Long QT syndrome 22 | 52
adult high grade glioma 22 | 2,148
pituitary cancer 22 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,289
Breast cancer 18 | 3,094
Pick disease 18 | 1,893
lung adenocarcinoma 18 | 2,713
posterior fossa group A ependymoma 18 | 1,511
pancreatic cancer 17 | 2,300
atypical teratoid/rhabdoid tumor 16 | 1,095
sonic hedgehog group medulloblastoma 16 | 1,482
ductal carcinoma in situ 15 | 1,745
invasive ductal carcinoma 15 | 2,950
cystic fibrosis 14 | 1,665
adrenocortical carcinoma 13 | 1,427
group 3 medulloblastoma 13 | 2,254
group 4 medulloblastoma 13 | 1,875
non-small cell lung cancer 13 | 2,798
interstitial cystitis 12 | 2,299
posterior fossa group B ependymoma 12 | 1,530
Chronic heart failure 11 | 46
astrocytoma 11 | 1,493
active Crohn's disease 10 | 918
colon cancer 10 | 1,475
ulcerative colitis 10 | 2,087
Episodic ataxia 9 | 17
Intellectual disability 9 | 573
Schnyder corneal dystrophy 9 | 23
gastric carcinoma 9 | 832
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
primary pancreatic ductal adenocarcinoma 9 | 1,271
Congestive heart failure 8 | 30
Poisoning by digitalis glycoside 8 | 8
active ulcerative colitis 8 | 477
breast carcinoma 8 | 1,614
diabetes mellitus 8 | 1,663
progressive supranuclear palsy 8 | 674
Down syndrome 7 | 548
Heart disease 7 | 279
Hyperaldosteronism 7 | 27
Hypertension 7 | 287
Hypokalemia 7 | 40
cutaneous lupus erythematosus 7 | 1,056
Alzheimer's disease 6 | 644
Brugada syndrome 6 | 26
Cancer 6 | 2,346
Osteoporosis 6 | 257
Parkinson's disease 6 | 364
fibroadenoma 6 | 557
nasopharyngeal carcinoma 6 | 1,056
tuberculosis and treatment for 6 months 6 | 686
Congenital long QT syndrome 5 | 8
Conn's syndrome 5 | 22
Diabetes Mellitus, Non-Insulin-Dependent 5 | 157
Duchenne muscular dystrophy 5 | 602
General anesthesia 5 | 53
Heart conduction disease 5 | 65
Hypertensive disease 5 | 193
Romano-Ward Syndrome 5 | 12
Seizures 5 | 95
Sensorineural hearing loss 5 | 107
Short QT syndrome 5 | 12
Type 2 diabetes mellitus 5 | 189
aldosterone-producing adenoma 5 | 664
chronic rhinosinusitis 5 | 512
nephrosclerosis 5 | 329
tuberculosis 5 | 1,557
Kidney disease 4 | 396
Migraine 4 | 79
Multiple myeloma 4 | 1,327
Waldenstrons macroglobulinemia 4 | 765
dermatomyositis 4 | 933
glioblastoma multiforme 4 | 347
hepatocellular carcinoma 4 | 532
pancreatic carcinoma 4 | 567
spina bifida 4 | 1,064

Tissue

Nervous System 129 | 18,561
Digestive Tract 128 | 18,473
Endocrine System 128 | 18,512
Urinary Tract 128 | 18,444
Female tissues 126 | 18,647
Liver and Pancreas 126 | 18,136
Cardiovascular System 125 | 17,958
Male tissues 125 | 17,969
Skin and soft tissues 125 | 18,115
Blood and immune system 124 | 17,995
Respiratory system 123 | 17,484

Target Family

Ion Channel 92 | 341
Transporter 22 | 473
Enzyme 11 | 4,146
Kinase 3 | 634
Non-IDG 1 | 11,971

UniProt Keyword

Potassium 129 | 129
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pyruvate kinase PKM PKM Tchem Kinase -3.09101 1313.5 672
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Potassium-transporting ATPase subunit beta ATP4B Tclin Transporter -0.76953 6.01 159
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.04732 117.9 108
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial BCKDHA Tbio Enzyme -2.78922 658.4 61
Tubulin--tyrosine ligase TTL Tchem Enzyme -1.29724 15.2 55
Potassium voltage-gated channel subfamily A member 3 KCNA3 Tclin Ion Channel -2.64735 493.0 284
Sodium/potassium-transporting ATPase subunit alpha-3 ATP1A3 Tclin Transporter -2.09703 131.9 103
G protein-activated inward rectifier potassium channel 4 KCNJ5 Tchem Ion Channel -2.24687 186.6 114
G protein-activated inward rectifier potassium channel 1 KCNJ3 Tchem Ion Channel -2.31340 205.5 237