Development Level

Tbio 78 | 10,625
Tclin 57 | 602
Tchem 24 | 1,890
Tdark 19 | 7,003

Collection

Eligible Ion Channel Proteins 22 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

decreased body weight 4 | 174
decreased total body fat amoun... 4 | 186
decreased lean body mass 3 | 195
enlarged heart 3 | 111
increased mean corpuscular vol... 3 | 91
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased exploration in new e... 2 | 9
decreased grip strength 2 | 123
decreased heart weight 2 | 44
increased or absent threshold ... 2 | 128
preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
abnormal QRS complex 1 | 25
abnormal bone mineralization 1 | 55
abnormal coat appearance 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal iris pigmentation 1 | 3
abnormal locomotor activation 1 | 26
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating creatini... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased fasted circulating g... 1 | 49
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased bone mineral content 1 | 92
increased caudal vertebrae num... 1 | 8
increased circulating chloride... 1 | 43
increased circulating phosphat... 1 | 24
increased heart rate 1 | 17
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased startle reflex 1 | 38
persistence of hyaloid vascula... 1 | 22
shortened RR interval 1 | 19
shortened ST segment 1 | 9
small superior vagus ganglion 1 | 20
small testis 1 | 37
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

medulloblastoma, large-cell 117 | 6,234
atypical teratoid / rhabdoid tumor 92 | 4,369
glioblastoma 92 | 5,572
psoriasis 70 | 6,685
pilocytic astrocytoma 69 | 3,086
oligodendroglioma 66 | 2,849
primitive neuroectodermal tumor 66 | 3,031
ovarian cancer 63 | 8,484
osteosarcoma 57 | 7,933
ependymoma 55 | 2,514
pediatric high grade glioma 52 | 2,712
Carcinoma 49 | 2,147
medulloblastoma 49 | 1,524
astrocytic glioma 48 | 2,241
Schizophrenia 47 | 501
adult high grade glioma 45 | 2,148
lung carcinoma 44 | 2,844
lung cancer 43 | 4,466
subependymal giant cell astrocytoma 41 | 2,287
General anesthesia 40 | 53
Epilepsy 39 | 346
Pick disease 38 | 1,893
Autistic Disorder 34 | 320
Breast cancer 34 | 3,094
pituitary cancer 33 | 1,972
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,289
posterior fossa group A ependymoma 28 | 1,511
invasive ductal carcinoma 27 | 2,950
malignant mesothelioma 27 | 3,162
group 4 medulloblastoma 26 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,988
Tonic-clonic epilepsy 25 | 47
astrocytoma 25 | 1,493
lung adenocarcinoma 24 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
Intellectual disability 21 | 573
Alcohol dependence 20 | 107
Bipolar Disorder 20 | 266
Local anesthesia 20 | 40
colon cancer 20 | 1,475
ductal carcinoma in situ 20 | 1,745
interstitial cystitis 19 | 2,299
non-small cell lung cancer 19 | 2,798
sonic hedgehog group medulloblastoma 19 | 1,482
Parkinson's disease 18 | 364
cystic fibrosis 18 | 1,665
Nicotine dependence 17 | 53
Amyotrophic Lateral Sclerosis 16 | 431
Anxiety 16 | 24
Insomnia 16 | 20
breast carcinoma 16 | 1,614
group 3 medulloblastoma 16 | 2,254
Lennox-Gastaut syndrome 15 | 34
Alzheimer's disease 14 | 644
Simple partial seizure 14 | 26
atypical teratoid/rhabdoid tumor 14 | 1,095
posterior fossa group B ependymoma 14 | 1,530
Cocaine-Related Disorders 13 | 88
Sedation as Adjunct to Anesthesia 13 | 15
pancreatic cancer 13 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
Epilepsy characterized by intractable complex partial seizures 12 | 28
Migraine Prevention 12 | 22
Peptic ulcer 12 | 22
Irritable bowel syndrome 11 | 59
Status Epilepticus 11 | 85
acute quadriplegic myopathy 11 | 1,157
tuberculosis 11 | 1,557
ulcerative colitis 11 | 2,087
Alcoholism 10 | 14
Down syndrome 10 | 548
Neuropathy 10 | 210
active Crohn's disease 10 | 918
adrenocortical carcinoma 10 | 1,427
Cancer 9 | 2,346
Seizures 9 | 95
Tetanus 9 | 66
Toxic encephalopathy 9 | 131
aldosterone-producing adenoma 9 | 664
gastric carcinoma 9 | 832
juvenile dermatomyositis 9 | 1,189
non primary Sjogren syndrome sicca 9 | 840
Alcohol withdrawal delirium 8 | 9
Arteriosclerotic Parkinsonism 8 | 8
Congenital myasthenic syndrome 8 | 28
Duchenne muscular dystrophy 8 | 602
Extrapyramidal disease 8 | 8
Induce Anterograde Amnesia 8 | 9
Major Depressive Disorder 8 | 106
Obesity 8 | 616
Panic disorder 8 | 55
Parkinsonism 8 | 19
Postencephalitic parkinsonism 8 | 12
Schizoaffective disorder 8 | 33
Spasticity 8 | 26
Substance Withdrawal Syndrome 8 | 52
dermatomyositis 8 | 933
glioblastoma multiforme 8 | 347
primary pancreatic ductal adenocarcinoma 8 | 1,271
progressive supranuclear palsy 8 | 674

Tissue

Female tissues 177 | 18,647
Endocrine System 176 | 18,512
Nervous System 176 | 18,561
Digestive Tract 175 | 18,473
Cardiovascular System 174 | 17,958
Liver and Pancreas 174 | 18,136
Urinary Tract 174 | 18,444
Blood and immune system 173 | 17,995
Male tissues 171 | 17,969
Skin and soft tissues 171 | 18,115
Respiratory system 170 | 17,484

Target Family

Non-IDG 86 | 11,971
Ion Channel 66 | 341
Enzyme 13 | 4,146
GPCR 8 | 406
Kinase 4 | 634
Epigenetic 1 | 242

UniProt Keyword

Postsynaptic cell membrane 178 | 178
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tchem Ion Channel -1.68717 47.7 33
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.70715 50.4 134
Acetylcholine receptor subunit delta CHRND Tclin Ion Channel -1.23749 17.4 128
Cytoplasmic polyadenylation element-binding protein 3 CPEB3 Tbio Non-IDG -1.28920 20.4 75
PH and SEC7 domain-containing protein 3 PSD3 Tbio Non-IDG -1.18771 15.6 120
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.39539 267.3 178
Calsyntenin-1 CLSTN1 Tbio Non-IDG -1.08669 14.3 106
Glycine receptor subunit beta GLRB Tclin Ion Channel -1.15613 15.9 85
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.23686 16.0 235