Development Level

Tbio 90 | 11,651
Tclin 58 | 612
Tdark 20 | 6,593
Tchem 17 | 1,388

Collection

Ion Channel: IDG Consortium (T... 15 | 99
RFA-RM-18-021 14 | 328
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

decreased total body fat amoun... 7 | 207
abnormal behavior 4 | 298
decreased body weight 4 | 161
increased mean corpuscular vol... 4 | 92
increased or absent threshold ... 4 | 101
preweaning lethality, complete... 4 | 979
increased lean body mass 3 | 172
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal cornea morphology 2 | 31
abnormal epididymis morphology 2 | 42
abnormal joint morphology 2 | 23
abnormal retina morphology 2 | 71
brachydactyly 2 | 19
decreased circulating HDL chol... 2 | 68
decreased exploration in new e... 2 | 11
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hyperactivity 2 | 148
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased circulating chloride... 2 | 41
increased heart weight 2 | 62
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
syndactyly 2 | 23
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal brain morphology 1 | 13
abnormal cecum morphology 1 | 7
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal iris pigmentation 1 | 4
abnormal locomotor behavior 1 | 24
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased cardiac muscle contr... 1 | 11
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged cecum 1 | 5
hydroencephaly 1 | 14
improved glucose tolerance 1 | 79
increased IgG2b level 1 | 1
increased cardiac muscle contr... 1 | 8
increased caudal vertebrae num... 1 | 7
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 149 | 11,493
medulloblastoma, large-cell 120 | 6,241
atypical teratoid / rhabdoid tumor 107 | 5,112
glioblastoma 100 | 5,792
ependymoma 90 | 4,679
adult high grade glioma 85 | 3,801
Schizophrenia 75 | 1,160
psoriasis 73 | 6,694
Astrocytoma, Pilocytic 68 | 3,081
oligodendroglioma 68 | 2,850
primitive neuroectodermal tumor 67 | 3,035
group 3 medulloblastoma 66 | 4,104
ovarian cancer 65 | 8,520
osteosarcoma 62 | 7,950
astrocytic glioma 61 | 2,597
Kidney cancer 59 | 2,613
lung cancer 55 | 4,740
lung carcinoma 45 | 2,843
Bipolar Disorder 44 | 666
Epilepsy 42 | 792
subependymal giant cell astrocytoma 42 | 2,287
General anesthesia 40 | 53
Breast cancer 39 | 3,578
Pick disease 39 | 1,894
Autistic Disorder 35 | 364
pituitary cancer 35 | 1,972
Alcoholic Intoxication, Chronic 32 | 289
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
Intellectual disability 27 | 1,016
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
invasive ductal carcinoma 27 | 2,951
malignant mesothelioma 27 | 3,232
group 4 medulloblastoma 26 | 1,855
Tonic-clonic epilepsy 25 | 47
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
lung adenocarcinoma 25 | 2,716
Depressive disorder 22 | 409
Mental Depression 22 | 333
non-small cell lung cancer 22 | 2,890
Autosomal recessive predisposition 21 | 1,442
Alcohol dependence 20 | 107
Local anesthesia 20 | 40
colon cancer 20 | 1,478
ductal carcinoma in situ 20 | 1,745
interstitial cystitis 20 | 2,312
Anxiety 19 | 136
Liver cancer 19 | 604
Major Depressive Disorder 19 | 301
Amyotrophic lateral sclerosis 18 | 451
Muscle hypotonia 18 | 571
Parkinson's disease 18 | 392
Seizures 18 | 596
cystic fibrosis 18 | 1,696
Melanoma 17 | 711
Mood Disorders 17 | 184
Nicotine dependence 17 | 54
breast carcinoma 17 | 1,638
Insomnia 16 | 20
Skin cancer 16 | 469
medulloblastoma 16 | 720
pancreatic cancer 16 | 2,398
tuberculosis 16 | 2,010
Alcoholism 15 | 45
Lennox-Gastaut syndrome 15 | 34
Cocaine-Related Disorders 14 | 92
Simple partial seizure 14 | 26
Unipolar Depression 14 | 250
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
pediatric high grade glioma 14 | 1,064
Alzheimer's disease 13 | 658
Dull intelligence 13 | 645
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Poor school performance 13 | 645
Sedation as Adjunct to Anesthesia 13 | 15
astrocytoma 13 | 1,146
Cognitive delay 12 | 608
Epilepsy characterized by intractable complex partial seizures 12 | 28
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
Migraine Prevention 12 | 23
Peptic Ulcer 12 | 27
Schizoaffective Disorder 12 | 55
acute quadriplegic myopathy 12 | 1,158
ulcerative colitis 12 | 1,819
Autism spectrum disorder 11 | 101
Infantile onset 11 | 238
Irritable bowel syndrome 11 | 60
Status Epilepticus 11 | 98
adrenocortical carcinoma 11 | 1,428
Endometrial cancer 10 | 311
Toxic encephalopathy 10 | 141
active Crohn's disease 10 | 922
aldosterone-producing adenoma 10 | 665
non primary Sjogren syndrome sicca 10 | 891
Cleft Palate 9 | 271
dermatomyositis 9 | 966
gastric carcinoma 9 | 807
juvenile dermatomyositis 9 | 1,187

Tissue

Endocrine System 181 | 18,159
Nervous System 178 | 16,725
Digestive Tract 172 | 17,369
Female tissues 171 | 17,400
Skin and soft tissues 170 | 17,230
Male tissues 166 | 17,142
Blood and immune system 162 | 16,909
Urinary Tract 160 | 16,678
Liver and Pancreas 157 | 16,750
Respiratory system 149 | 16,393
Cardiovascular System 128 | 15,192

Target Family

Non-IDG 90 | 12,091
Ion Channel 67 | 344
Enzyme 14 | 4,145
GPCR 9 | 408
Kinase 4 | 634
Epigenetic 1 | 242

UniProt Keyword

Postsynaptic cell membrane 185 | 185
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Protein TANC1 TANC1 Tdark Non-IDG -1.18264 15.5 31
Disks large homolog 2 DLG2 Tbio Non-IDG -1.75838 53.6 227
Leucine-rich repeat and fibronectin type-III domain-containing protein 2 LRFN2 Tbio Non-IDG -0.81315 6.12 97
Leucine-rich repeat and fibronectin type-III domain-containing protein 3 LRFN3 Tdark Non-IDG -0.48565 2.89 63
SHC-transforming protein 4 SHC4 Tbio Non-IDG -2.45096 295.5 129
Leucine-rich repeat-containing protein 4C LRRC4C Tbio Non-IDG -2.22551 163.3 161
Leucine-rich repeat transmembrane neuronal protein 2 LRRTM2 Tbio Non-IDG -0.86860 8.30 115
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.06393 1238.4 694
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.45026 285.7 241