Development Level

Tbio 42 | 11,445
Tdark 5 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
decreased bone mineral content 2 | 151
embryonic lethality prior to o... 2 | 239
abnormal embryo size 1 | 220
abnormal joint morphology 1 | 23
abnormal maxilla morphology 1 | 17
abnormal spleen morphology 1 | 55
brachydactyly 1 | 19
decreased body weight 1 | 161
decreased cardiac muscle contr... 1 | 11
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased circulating calcium ... 1 | 34
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased heart rate variabili... 1 | 7
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
small seminal vesicle 1 | 10
syndactyly 1 | 23

Disease

osteosarcoma 28 | 7,950
ovarian cancer 28 | 8,520
Carcinoma 27 | 11,493
medulloblastoma, large-cell 20 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
glioblastoma 18 | 5,792
atypical teratoid / rhabdoid tumor 16 | 5,112
psoriasis 16 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
invasive ductal carcinoma 15 | 2,951
ependymoma 14 | 4,679
group 3 medulloblastoma 13 | 4,104
lung cancer 12 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
adult high grade glioma 11 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung carcinoma 11 | 2,843
Breast cancer 10 | 3,578
group 4 medulloblastoma 10 | 1,855
malignant mesothelioma 10 | 3,232
subependymal giant cell astrocytoma 10 | 2,287
Pick disease 9 | 1,894
tuberculosis 9 | 2,010
Astrocytoma, Pilocytic 8 | 3,081
non-small cell lung cancer 8 | 2,890
oligodendroglioma 8 | 2,850
primitive neuroectodermal tumor 8 | 3,035
astrocytic glioma 7 | 2,597
ductal carcinoma in situ 7 | 1,745
pancreatic cancer 7 | 2,398
spina bifida 7 | 1,074
Rheumatoid arthritis 6 | 1,191
interstitial cystitis 6 | 2,312
non primary Sjogren syndrome sicca 6 | 891
pediatric high grade glioma 6 | 1,064
ulcerative colitis 6 | 1,819
Intellectual disability 5 | 1,016
active Crohn's disease 5 | 922
cystic fibrosis 5 | 1,696
lung adenocarcinoma 5 | 2,716
Autosomal recessive predisposition 4 | 1,442
Dull intelligence 4 | 645
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Newborn respiratory distress syndrome 4 | 10
Poor school performance 4 | 645
Sengers syndrome 4 | 18
Waldenstrons macroglobulinemia 4 | 765
breast carcinoma 4 | 1,638
gastric carcinoma 4 | 807
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
Barth syndrome 3 | 23
Hepatomegaly 3 | 285
Polycystic ovary syndrome 3 | 360
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
esophageal adenocarcinoma 3 | 737
3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome 2 | 2
Arthritis, Juvenile 2 | 126
Attention deficit hyperactivity disorder 2 | 278
Brachydactyly 2 | 156
Chemical and Drug Induced Liver Injury 2 | 195
Chronic Lymphocytic Leukemia 2 | 262
Juvenile arthritis 2 | 126
Leigh disease 2 | 100
Lipodystrophy 2 | 40
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Myopathy 2 | 185
Neutral lipid storage disease 2 | 12
Nystagmus 2 | 317
Obesity 2 | 678
Sensorineural Hearing Loss (disorder) 2 | 284
Sleeping sickness 2 | 37
Spinal Dysraphism 2 | 12
Steatohepatitis 2 | 44
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
pancreatic carcinoma 2 | 562
Anteriorly placed anus 1 | 7
Chromosome 1q21.1 deletion syndrome 1 | 12
Congenital ichthyosiform erythroderma 1 | 28
Cutis marmorata 1 | 32
Deafness dystonia syndrome 1 | 21
Ectropion 1 | 38
Flexion contracture - elbow 1 | 32
Hyperphagia 1 | 23
Increased appetite (finding) 1 | 23
Insulinoma 1 | 24
Neurodegenerative Diseases 1 | 38
Postnatal growth retardation 1 | 57

Tissue

Digestive Tract 49 | 17,369
Endocrine System 49 | 18,159
Female tissues 49 | 17,400
Nervous System 49 | 16,725
Blood and immune system 48 | 16,909
Cardiovascular System 48 | 15,192
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Respiratory system 48 | 16,393
Skin and soft tissues 48 | 17,230
Urinary Tract 48 | 16,678

Target Family

Enzyme 41 | 4,145
Kinase 4 | 634
Non-IDG 4 | 12,091

UniProt Keyword

Phospholipid metabolism 49 | 49
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Choline-phosphate cytidylyltransferase B PCYT1B Tbio Enzyme -1.46937 28.8 40
Cardiolipin synthase (CMP-forming) CRLS1 Tbio Enzyme -0.87118 6.24 100
Glycerol-3-phosphate acyltransferase 1, mitochondrial GPAM Tbio Enzyme -1.93041 83.4 177
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon AGPAT5 Tbio Enzyme -0.79526 4.42 180
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
Cholinephosphotransferase 1 CHPT1 Tbio Enzyme -1.42313 23.5 80
Ethanolamine kinase 1 ETNK1 Tbio Kinase -1.59702 38.8 152
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 PTPMT1 Tbio Enzyme -1.36243 23.0 109
Phospholipase ABHD3 ABHD3 Tbio Enzyme -0.41218 2.23 91
Serine incorporator 4 SERINC4 Tdark Non-IDG 0.00000 33