Development Level

Tbio 30 | 11,445
Tchem 10 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased bone mineral content 4 | 151
decreased lean body mass 3 | 135
decreased vertical activity 3 | 208
increased total body fat amoun... 3 | 134
abnormal heart morphology 2 | 162
enlarged heart 2 | 210
increased monocyte cell number 2 | 63
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased erythrocyte cell num... 1 | 39
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
prolonged ST segment 1 | 36
small testis 1 | 58
tremors 1 | 39

Disease

Cancer 31 | 2,499
psoriasis 23 | 6,694
Carcinoma 21 | 11,493
diabetes mellitus 18 | 1,728
lung cancer 17 | 4,740
osteosarcoma 17 | 7,950
glioblastoma 16 | 5,792
Diarrhea 13 | 253
Hypertension 13 | 396
Kidney disease 13 | 430
Obesity 13 | 678
Rheumatoid arthritis 13 | 1,191
Schizophrenia 13 | 1,160
ovarian cancer 13 | 8,520
Thrombocytopenia 12 | 197
colon cancer 12 | 1,478
interstitial cystitis 12 | 2,312
Bipolar Disorder 11 | 666
Hypertensive disease 11 | 292
Liver disease 11 | 237
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
invasive ductal carcinoma 11 | 2,951
malignant mesothelioma 11 | 3,232
medulloblastoma, large-cell 11 | 6,241
Anemia 10 | 365
Autosomal recessive predisposition 10 | 1,442
Breast cancer 10 | 3,578
Depressive disorder 10 | 409
Heart disease 10 | 306
Heart failure 10 | 162
Hypersensitivity reaction type II disease 10 | 253
Liver Cirrhosis, Experimental 10 | 769
Vascular disease 10 | 319
lung carcinoma 10 | 2,843
pancreatic cancer 10 | 2,398
Arthritis 9 | 290
Asthma 9 | 385
Astrocytoma, Pilocytic 9 | 3,081
Cerebrovascular disease 9 | 238
Hepatitis C 9 | 94
Lung disease 9 | 142
Melanoma 9 | 711
Myocardial Infarction 9 | 151
adult high grade glioma 9 | 3,801
cystic fibrosis 9 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
tuberculosis 9 | 2,010
Acquired immunodeficiency syndrome 8 | 197
Adenoma 8 | 167
Arthritis, Rheumatoid 8 | 174
Atherosclerosis 8 | 291
Hepatitis B 8 | 108
Hypoglycemia 8 | 152
Hypotension 8 | 82
Hypothyroidism 8 | 122
Inflammation 8 | 120
Pulmonary Fibrosis 8 | 106
Seizures 8 | 596
Weight decreased 8 | 103
group 4 medulloblastoma 8 | 1,855
lung adenocarcinoma 8 | 2,716
non-small cell lung cancer 8 | 2,890
Coronary artery disease 7 | 268
Fever 7 | 138
Hepatitis 7 | 67
Hypopituitarism 7 | 40
Major Depressive Disorder 7 | 301
Multiple Sclerosis 7 | 540
Pain 7 | 103
Unipolar Depression 7 | 250
Venous Thrombosis 7 | 47
cutaneous lupus erythematosus 7 | 1,057
ductal carcinoma in situ 7 | 1,745
ulcerative colitis 7 | 1,819
Acromegaly 6 | 51
Anorexia nervosa 6 | 80
Atopic dermatitis 6 | 952
Brain Ischemia 6 | 110
Chemical and Drug Induced Liver Injury 6 | 195
Dermatitis 6 | 157
Epilepsy 6 | 792
Inflammatory bowel disease 6 | 151
Leukopenia 6 | 72
Liver Cirrhosis 6 | 181
Mammary Neoplasms 6 | 425
Mental Depression 6 | 333
Neuropathy 6 | 261
Pituitary adenoma 6 | 38
Pneumonia 6 | 174
Prostatic Neoplasms 6 | 495
Proteinuria 6 | 144
Pulmonary embolism 6 | 55
adrenocortical carcinoma 6 | 1,428
gastric carcinoma 6 | 807
nasopharyngeal carcinoma 6 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
periodontitis 6 | 293

Tissue

Digestive Tract 41 | 17,369
Endocrine System 40 | 18,159
Female tissues 40 | 17,400
Liver and Pancreas 40 | 16,750
Blood and immune system 39 | 16,909
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Male tissues 37 | 17,142
Respiratory system 37 | 16,393
Nervous System 34 | 16,725
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 36 | 12,091
Enzyme 9 | 4,145
Transcription Factor 1 | 1,400

UniProt Keyword

Pharmaceutical 46 | 46
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Somatostatin SST Tbio Non-IDG -4.14886 13572.0 397
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
Forkhead box protein O4 FOXO4 Tbio Transcription Factor -2.43923 278.0 720
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Coagulation factor VIII F8 Tbio Non-IDG -3.59602 3983.5 652
Alpha-galactosidase A GLA Tclin Enzyme -3.00418 985.0 249
B-lymphocyte antigen CD20 MS4A1 Tclin Non-IDG -1.94302 79.5 2278
Apoptosis regulatory protein Siva SIVA1 Tbio Non-IDG -1.84195 71.7 191
Interleukin-2 IL2 Tchem Non-IDG -4.37903 24027.6 1518
Deoxyribonuclease-1 DNASE1 Tchem Enzyme -2.60894 369.4 173