Development Level

Tbio 162 | 11,651
Tclin 70 | 612
Tchem 53 | 1,388
Tdark 46 | 6,593

Collection

RFA-RM-18-021 10 | 328
GPCR: IDG Consortium (Targets) 6 | 126
Ion Channel: IDG Consortium (T... 3 | 99
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 12 | 499
abnormal embryo size 7 | 220
abnormal behavior 6 | 298
decreased total body fat amoun... 6 | 207
decreased vertical activity 6 | 208
embryonic lethality prior to t... 6 | 278
hyperactivity 6 | 148
decreased body weight 5 | 161
enlarged heart 5 | 210
improved glucose tolerance 5 | 79
decreased hemoglobin content 4 | 68
decreased lean body mass 4 | 135
increased circulating chloride... 4 | 41
increased circulating sodium l... 4 | 71
increased startle reflex 4 | 112
abnormal sleep behavior 3 | 70
decreased bone mineral content 3 | 151
decreased hematocrit 3 | 46
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
decreased prepulse inhibition 3 | 82
decreased startle reflex 3 | 75
embryonic growth retardation 3 | 106
enlarged spleen 3 | 41
impaired pupillary reflex 3 | 26
increased erythrocyte cell num... 3 | 39
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
increased total body fat amoun... 3 | 134
limb grasping 3 | 41
prenatal lethality 3 | 28
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
cardiovascular system phenotyp... 2 | 36
convulsive seizures 2 | 13
decreased anxiety-related resp... 2 | 12
decreased circulating HDL chol... 2 | 68
decreased circulating aspartat... 2 | 34
decreased circulating insulin ... 2 | 76
decreased circulating sodium l... 2 | 22
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased exploration in new e... 2 | 11
decreased fasted circulating g... 2 | 65
decreased heart left ventricle... 2 | 28
decreased mean corpuscular vol... 2 | 79
hypoactivity 2 | 132
increased blood urea nitrogen ... 2 | 48
increased fasted circulating g... 2 | 76
increased mean corpuscular hem... 2 | 36
pallor 2 | 34
short tibia 2 | 97
thin ventricular wall 2 | 24
tremors 2 | 39
abnormal gait 1 | 69
abnormal spleen morphology 1 | 55
anophthalmia 1 | 33
cataract 1 | 92
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged ovary 1 | 2
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
iris synechia 1 | 3
polycystic kidney 1 | 15
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small thymus 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 204 | 11,493
glioblastoma 150 | 5,792
medulloblastoma, large-cell 150 | 6,241
ovarian cancer 146 | 8,520
osteosarcoma 144 | 7,950
psoriasis 131 | 6,694
atypical teratoid / rhabdoid tumor 127 | 5,112
ependymoma 118 | 4,679
adult high grade glioma 99 | 3,801
Astrocytoma, Pilocytic 93 | 3,081
lung cancer 91 | 4,740
group 3 medulloblastoma 85 | 4,104
oligodendroglioma 79 | 2,850
astrocytic glioma 77 | 2,597
lung carcinoma 77 | 2,843
primitive neuroectodermal tumor 76 | 3,035
Cancer 74 | 2,499
Breast cancer 70 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 68 | 2,955
invasive ductal carcinoma 67 | 2,951
Schizophrenia 64 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 64 | 2,989
lung adenocarcinoma 63 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 62 | 3,291
non-small cell lung cancer 62 | 2,890
subependymal giant cell astrocytoma 61 | 2,287
interstitial cystitis 58 | 2,312
malignant mesothelioma 58 | 3,232
pancreatic cancer 56 | 2,398
group 4 medulloblastoma 50 | 1,855
Pick disease 49 | 1,894
ductal carcinoma in situ 48 | 1,745
colon cancer 47 | 1,478
tuberculosis 44 | 2,010
ulcerative colitis 43 | 1,819
diabetes mellitus 41 | 1,728
pituitary cancer 40 | 1,972
Kidney cancer 39 | 2,613
Autosomal recessive predisposition 37 | 1,442
Bipolar Disorder 37 | 666
Epilepsy 37 | 792
Obesity 34 | 678
cutaneous lupus erythematosus 34 | 1,057
juvenile dermatomyositis 34 | 1,187
Depressive disorder 32 | 409
breast carcinoma 32 | 1,638
cystic fibrosis 31 | 1,696
Hypertension 30 | 396
adrenocortical carcinoma 30 | 1,428
Alcoholic Intoxication, Chronic 28 | 289
Alzheimer's disease 28 | 658
astrocytoma 28 | 1,146
Down syndrome 27 | 499
Mental Depression 27 | 333
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
Intellectual disability 26 | 1,016
Liver Cirrhosis, Experimental 25 | 769
Multiple myeloma 24 | 1,332
Parkinson's disease 24 | 392
dermatomyositis 24 | 966
Multiple Sclerosis 23 | 540
Rheumatoid arthritis 22 | 1,191
primary Sjogren syndrome 21 | 735
spina bifida 21 | 1,074
Heart disease 20 | 306
Seizures 20 | 596
active Crohn's disease 20 | 922
acute quadriplegic myopathy 20 | 1,158
primary pancreatic ductal adenocarcinoma 20 | 1,109
Mood Disorders 19 | 184
Coronary artery disease 18 | 268
Hypertensive disease 18 | 292
Vascular disease 18 | 319
nasopharyngeal carcinoma 18 | 1,058
progressive supranuclear palsy 18 | 676
Asthma 17 | 385
Cerebrovascular disease 17 | 238
Duchenne muscular dystrophy 17 | 601
Dull intelligence 17 | 645
Low intelligence 17 | 645
Major Depressive Disorder 17 | 301
Mental Retardation 17 | 645
Mental deficiency 17 | 645
Poor school performance 17 | 645
gastric carcinoma 17 | 807
pediatric high grade glioma 17 | 1,064
Atherosclerosis 16 | 291
Attention deficit hyperactivity disorder 16 | 278
Melanoma 16 | 711
fibroadenoma 16 | 559
pancreatic carcinoma 16 | 562
Autistic Disorder 15 | 364
Neurodegenerative disease 15 | 414
mucosa-associated lymphoid tissue lymphoma 15 | 484
non primary Sjogren syndrome sicca 15 | 891
Chronic Lymphocytic Leukemia 14 | 262
Cocaine-Related Disorders 14 | 92
Liver cancer 14 | 604
Polycystic ovary syndrome 14 | 360
Waldenstrons macroglobulinemia 14 | 765

Tissue

Endocrine System 323 | 18,159
Digestive Tract 308 | 17,369
Female tissues 306 | 17,400
Nervous System 304 | 16,725
Skin and soft tissues 302 | 17,230
Male tissues 300 | 17,142
Blood and immune system 299 | 16,909
Liver and Pancreas 292 | 16,750
Urinary Tract 292 | 16,678
Respiratory system 287 | 16,393
Cardiovascular System 265 | 15,192

Target Family

Non-IDG 144 | 12,091
GPCR 73 | 408
Enzyme 67 | 4,145
Ion Channel 23 | 344
Kinase 14 | 634
Transporter 6 | 473
Nuclear Receptor 3 | 48
Epigenetic 1 | 242

UniProt Keyword

Palmitate 331 | 331
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paralemmin-3 PALM3 Tbio Non-IDG -0.66901 5.71 76
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Disks large homolog 2 DLG2 Tbio Non-IDG -1.75838 53.6 227
Claudin-15 CLDN15 Tbio Non-IDG -1.33932 19.3 154
Opsin-5 OPN5 Tbio GPCR -1.19753 14.2 151
Palmitoyltransferase ZDHHC5 ZDHHC5 Tbio Enzyme -0.94454 9.00 61
DnaJ homolog subfamily C member 5B DNAJC5B Tdark Non-IDG -0.62006 4.33 67
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Sphingosine 1-phosphate receptor 4 S1PR4 Tclin GPCR -1.78966 58.4 256
Palmitoyltransferase ZDHHC7 ZDHHC7 Tbio Enzyme -1.01816 7.69 109