Development Level

Tbio 138 | 10,625
Tclin 70 | 602
Tchem 65 | 1,890
Tdark 49 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 9 | 143
Eligible Ion Channel Proteins 4 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
preweaning lethality, incomple... 8 | 260
decreased body weight 6 | 174
abnormal behavior 5 | 226
decreased bone mineral content 4 | 157
decreased prepulse inhibition 4 | 52
decreased total body fat amoun... 4 | 186
hyperactivity 4 | 108
decreased circulating triglyce... 3 | 83
decreased neutrophil cell numb... 3 | 37
embryonic lethality prior to t... 3 | 187
increased circulating HDL chol... 3 | 63
increased circulating chloride... 3 | 43
increased circulating sodium l... 3 | 71
increased fasted circulating g... 3 | 68
increased total body fat amoun... 3 | 57
limb grasping 3 | 35
tremors 3 | 34
abnormal bone mineralization 2 | 55
abnormal coat/hair pigmentatio... 2 | 54
abnormal embryo size 2 | 112
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
abnormal sleep behavior 2 | 63
convulsive seizures 2 | 11
decreased anxiety-related resp... 2 | 12
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased circulating glycerol... 2 | 19
decreased circulating insulin ... 2 | 75
decreased circulating phosphat... 2 | 15
decreased exploration in new e... 2 | 9
decreased fasted circulating g... 2 | 49
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
decreased mean corpuscular vol... 2 | 50
decreased startle reflex 2 | 48
decreased threshold for audito... 2 | 32
enlarged spleen 2 | 26
hypoactivity 2 | 89
impaired pupillary reflex 2 | 14
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased bone mineral content 2 | 92
increased circulating calcium ... 2 | 32
increased erythrocyte cell num... 2 | 26
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal lip morphology 1 | 2
abnormal rib morphology 1 | 28
abnormal spleen morphology 1 | 36
abnormal whole-body plethysmog... 1 | 4
cardiovascular system phenotyp... 1 | 35
decreased CD4-positive, CD25-p... 1 | 24
decreased CD5-positive Ly6C-po... 1 | 4
decreased Ly6C low monocyte nu... 1 | 23
decreased body length 1 | 108
decreased cervical vertebrae n... 1 | 12
decreased effector memory CD8-... 1 | 24
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean platelet volume 1 | 12
decreased monocyte cell number 1 | 28
decreased pulmonary respirator... 1 | 4
dilated heart left ventricle 1 | 10
enlarged ovary 1 | 1
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased body weight 1 | 42
increased caudal vertebrae num... 1 | 8
increased circulating alkaline... 1 | 119
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased exploration in new e... 1 | 56
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased rib number 1 | 41
increased vertical activity 1 | 18
iris synechia 1 | 1
mydriasis 1 | 9
oligodactyly 1 | 14
pallor 1 | 13
polydactyly 1 | 22
short tibia 1 | 82
small spleen 1 | 11
small thymus 1 | 11
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

medulloblastoma, large-cell 147 | 6,234
glioblastoma 143 | 5,572
ovarian cancer 142 | 8,484
osteosarcoma 139 | 7,933
psoriasis 127 | 6,685
atypical teratoid / rhabdoid tumor 98 | 4,369
pilocytic astrocytoma 91 | 3,086
lung cancer 85 | 4,466
oligodendroglioma 77 | 2,849
primitive neuroectodermal tumor 75 | 3,031
lung carcinoma 73 | 2,844
Cancer 70 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 67 | 2,956
invasive ductal carcinoma 67 | 2,950
Breast cancer 66 | 3,094
pediatric high grade glioma 65 | 2,712
ependymoma 64 | 2,514
astrocytic glioma 63 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 61 | 2,988
lung adenocarcinoma 60 | 2,713
intraductal papillary-mucinous neoplasm (IPMN) 59 | 3,289
non-small cell lung cancer 59 | 2,798
subependymal giant cell astrocytoma 59 | 2,287
interstitial cystitis 57 | 2,299
malignant mesothelioma 54 | 3,162
pancreatic cancer 52 | 2,300
adult high grade glioma 50 | 2,148
ulcerative colitis 50 | 2,087
Pick disease 47 | 1,893
ductal carcinoma in situ 47 | 1,745
medulloblastoma 47 | 1,524
colon cancer 44 | 1,475
group 4 medulloblastoma 43 | 1,875
astrocytoma 41 | 1,493
pituitary cancer 39 | 1,972
atypical teratoid/rhabdoid tumor 38 | 1,095
diabetes mellitus 38 | 1,663
group 3 medulloblastoma 38 | 2,254
Carcinoma 37 | 2,147
posterior fossa group A ependymoma 35 | 1,511
Schizophrenia 34 | 501
juvenile dermatomyositis 34 | 1,189
tuberculosis 34 | 1,557
cutaneous lupus erythematosus 33 | 1,056
posterior fossa group B ependymoma 33 | 1,530
Obesity 31 | 616
breast carcinoma 30 | 1,614
adrenocortical carcinoma 29 | 1,427
cystic fibrosis 29 | 1,665
Down syndrome 27 | 548
Epilepsy 27 | 346
Alzheimer's disease 25 | 644
Multiple myeloma 24 | 1,327
Parkinson's disease 24 | 364
dermatomyositis 24 | 933
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
sonic hedgehog group medulloblastoma 24 | 1,482
Rheumatoid Arthritis 22 | 1,160
primary Sjogren syndrome 22 | 789
primary pancreatic ductal adenocarcinoma 21 | 1,271
Heart disease 20 | 279
Hypertension 20 | 287
Multiple Sclerosis 20 | 498
active Crohn's disease 20 | 918
Cerebrovascular disease 19 | 231
acute quadriplegic myopathy 19 | 1,157
spina bifida 19 | 1,064
nasopharyngeal carcinoma 18 | 1,056
Duchenne muscular dystrophy 17 | 602
gastric carcinoma 17 | 832
pancreatic carcinoma 17 | 567
progressive supranuclear palsy 17 | 674
Asthma 16 | 349
Autistic Disorder 16 | 320
Hypertensive disease 16 | 193
Intellectual disability 16 | 573
Atherosclerosis 15 | 275
Coronary artery disease 15 | 240
mucosa-associated lymphoid tissue lymphoma 15 | 480
Chronic Lymphocytic Leukemia 14 | 242
IGA Glomerulonephritis 14 | 454
fibroadenoma 14 | 557
Alcohol dependence 13 | 107
Cocaine-Related Disorders 13 | 88
Kidney disease 13 | 396
Mammary Neoplasms 13 | 410
Pain agnosia 13 | 99
Substance Withdrawal Syndrome 13 | 52
Waldenstrons macroglobulinemia 13 | 765
esophageal adenocarcinoma 13 | 737
non primary Sjogren syndrome sicca 13 | 840
Amyotrophic Lateral Sclerosis 12 | 431
Atopic dermatitis 12 | 944
Attention deficit hyperactivity disorder 12 | 156
Common cold 12 | 63
Endometriosis 12 | 535
Local anesthesia 12 | 40
Neurodegenerative disease 12 | 383
Stomach Neoplasms 12 | 282
Vascular disease 12 | 281

Tissue

Nervous System 308 | 18,561
Digestive Tract 307 | 18,473
Endocrine System 307 | 18,512
Urinary Tract 307 | 18,444
Female tissues 305 | 18,647
Cardiovascular System 303 | 17,958
Male tissues 303 | 17,969
Liver and Pancreas 302 | 18,136
Skin and soft tissues 302 | 18,115
Blood and immune system 297 | 17,995
Respiratory system 295 | 17,484

Target Family

Non-IDG 138 | 11,971
GPCR 73 | 406
Enzyme 66 | 4,146
Ion Channel 21 | 341
Kinase 14 | 634
Transporter 6 | 473
Nuclear Receptor 3 | 48
Epigenetic 1 | 242

UniProt Keyword

Palmitate 322 | 322
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Apolipoprotein A-I APOA1 Tchem Non-IDG -3.60439 3516.7 901
Neuropeptides B/W receptor type 2 NPBWR2 Tbio GPCR -1.14202 8.84 57
Stathmin-2 STMN2 Tbio Non-IDG -1.95188 90.0 305
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Cytoskeleton-associated protein 4 CKAP4 Tbio Non-IDG -1.40375 25.5 174
Band 3 anion transport protein SLC4A1 Tbio Transporter -3.02453 1271.7 133
Endothelin B receptor EDNRB Tclin GPCR -3.24561 1672.0 289
Regulator of G-protein signaling 16 RGS16 Tbio Non-IDG -1.59717 42.2 162