Development Level

Tbio 21 | 11,651
Tchem 9 | 1,388
Tdark 1 | 6,593

IMPC Phenotype

decreased circulating serum al... 2 | 82
increased blood urea nitrogen ... 2 | 48
increased circulating alkaline... 2 | 122
abnormal lens morphology 1 | 81
abnormal spine curvature 1 | 9
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
pallor 1 | 34
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15

Disease

ovarian cancer 17 | 8,520
Carcinoma 15 | 11,493
Cancer 14 | 2,499
diabetes mellitus 13 | 1,728
psoriasis 13 | 6,694
glioblastoma 10 | 5,792
osteosarcoma 10 | 7,950
Breast cancer 9 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
atypical teratoid / rhabdoid tumor 8 | 5,112
cystic fibrosis 8 | 1,696
group 3 medulloblastoma 8 | 4,104
lung adenocarcinoma 8 | 2,716
Alzheimer's disease 7 | 658
Autosomal recessive predisposition 7 | 1,442
Carcinoma, Hepatocellular 7 | 228
Kidney disease 7 | 430
Liver carcinoma 7 | 240
ependymoma 7 | 4,679
invasive ductal carcinoma 7 | 2,951
malignant mesothelioma 7 | 3,232
Coronary artery disease 6 | 268
Endometriosis 6 | 540
Obesity 6 | 678
Schizophrenia 6 | 1,160
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
juvenile dermatomyositis 6 | 1,187
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
pancreatic cancer 6 | 2,398
Atherosclerosis 5 | 291
Cerebrovascular disease 5 | 238
Hypertension 5 | 396
Intellectual disability 5 | 1,016
Liver Cirrhosis, Experimental 5 | 769
Neurodegenerative disease 5 | 414
Polycystic ovary syndrome 5 | 360
adrenocortical carcinoma 5 | 1,428
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
primary pancreatic ductal adenocarcinoma 5 | 1,109
primitive neuroectodermal tumor 5 | 3,035
Amyloidosis 4 | 67
Arthritis 4 | 290
Astrocytoma, Pilocytic 4 | 3,081
Atopic dermatitis 4 | 952
Brain disease 4 | 96
Cardiomyopathy, Dilated 4 | 83
Cataract 4 | 297
Cognitive delay 4 | 608
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Dull intelligence 4 | 645
Esophageal Neoplasms 4 | 69
Global developmental delay 4 | 608
Hypertensive disease 4 | 292
Hypoxia 4 | 33
Inflammation 4 | 120
Low intelligence 4 | 645
Lung Neoplasms 4 | 232
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Multiple Sclerosis 4 | 540
Multiple myeloma 4 | 1,332
Parkinson's disease 4 | 392
Poor school performance 4 | 645
Seizures 4 | 596
Toxic encephalopathy 4 | 141
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
nasopharyngeal carcinoma 4 | 1,058
non-small cell lung cancer 4 | 2,890
non-small cell lung carcinoma 4 | 317
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
ulcerative colitis 4 | 1,819
Amyotrophic lateral sclerosis 3 | 451
Bipolar Disorder 3 | 666
Colonic Neoplasms 3 | 142
Epilepsy 3 | 792
Heart disease 3 | 306
Lipid metabolism disorder 3 | 114
Lung disease 3 | 142
Neoplasm Invasiveness 3 | 161
Pick disease 3 | 1,894
Vascular disease 3 | 319
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
dermatomyositis 3 | 966
nephrosclerosis 3 | 333
pituitary cancer 3 | 1,972
pterygium 3 | 76
tuberculosis 3 | 2,010

Tissue

Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678
Blood and immune system 26 | 16,909
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Cardiovascular System 25 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 8 | 4,145
Transcription Factor 3 | 1,400

UniProt Keyword

Oxidation 31 | 31
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 ALKBH3 Tchem Enzyme -1.51372 33.2 194
Arylsulfatase I ARSI Tbio Enzyme -2.01048 99.4 129
Alpha-crystallin A chain CRYAA Tbio Non-IDG -2.84905 682.1 234
Glyceraldehyde-3-phosphate dehydrogenase GAPDH Tchem Enzyme -3.68189 4548.4 1886
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976
Apolipoprotein A-II APOA2 Tbio Non-IDG -2.81123 595.2 420
Beta-actin-like protein 2 ACTBL2 Tbio Non-IDG -0.75651 5.61 47
Mitochondrial brown fat uncoupling protein 1 UCP1 Tbio Non-IDG -3.12565 1273.2 279
Alpha-crystallin B chain CRYAB Tbio Non-IDG -2.29243 192.0 1100