Development Level

Tbio 28 | 11,445
Tdark 5 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

abnormal seminal vesicle morph... 2 | 114
abnormal testis morphology 2 | 43
decreased vertical activity 2 | 208
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
decreased circulating insulin ... 1 | 76
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased mean corpuscular vol... 1 | 79
enlarged heart 1 | 210
enlarged testis 1 | 6
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
small testis 1 | 58

Disease

Carcinoma 24 | 11,493
lung cancer 19 | 4,740
ovarian cancer 19 | 8,520
glioblastoma 18 | 5,792
atypical teratoid / rhabdoid tumor 17 | 5,112
psoriasis 17 | 6,694
non-small cell lung cancer 16 | 2,890
osteosarcoma 16 | 7,950
lung adenocarcinoma 14 | 2,716
invasive ductal carcinoma 13 | 2,951
malignant mesothelioma 13 | 3,232
medulloblastoma, large-cell 13 | 6,241
ependymoma 12 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Astrocytoma, Pilocytic 11 | 3,081
colon cancer 11 | 1,478
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
pancreatic cancer 11 | 2,398
breast carcinoma 10 | 1,638
cystic fibrosis 10 | 1,696
ductal carcinoma in situ 10 | 1,745
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Cancer 9 | 2,499
adult high grade glioma 9 | 3,801
lung carcinoma 9 | 2,843
ulcerative colitis 9 | 1,819
Atopic dermatitis 8 | 952
Breast cancer 8 | 3,578
primary pancreatic ductal adenocarcinoma 8 | 1,109
Duchenne muscular dystrophy 7 | 601
Osteoporosis 7 | 363
adrenocortical carcinoma 7 | 1,428
fibroadenoma 7 | 559
pituitary cancer 7 | 1,972
Autosomal recessive predisposition 6 | 1,442
Osteoarthritis 6 | 184
astrocytic glioma 6 | 2,597
gastric carcinoma 6 | 807
interstitial lung disease 6 | 298
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Mental and motor retardation 5 | 608
Rheumatoid arthritis 5 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
cutaneous lupus erythematosus 5 | 1,057
esophageal adenocarcinoma 5 | 737
group 4 medulloblastoma 5 | 1,855
oligodendroglioma 5 | 2,850
pediatric high grade glioma 5 | 1,064
Abortion, Spontaneous 4 | 109
Cleft Lip 4 | 141
Cleft Palate 4 | 271
Endometriosis 4 | 540
Hypertension 4 | 396
Hypoplastic mandible condyle 4 | 275
Hypotrophic malar bone 4 | 129
Kidney cancer 4 | 2,613
Malar flattening 4 | 129
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Muscle hypotonia 4 | 571
Spontaneous abortion 4 | 113
active Crohn's disease 4 | 922
chronic rhinosinusitis 4 | 512
juvenile dermatomyositis 4 | 1,187
limb girdle muscular dystrophy 2A 4 | 213
tuberculosis 4 | 2,010
Acquired scoliosis 3 | 281
Alzheimer's disease 3 | 658
Arthritis, Rheumatoid 3 | 174
Atherosclerosis 3 | 291
Breast Neoplasms 3 | 445
Byzanthine arch palate 3 | 194
Concave bridge of nose 3 | 195
Coronary artery disease 3 | 268
Curvature of spine 3 | 282
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Epilepsy 3 | 792
Exophthalmos 3 | 112
Frontal bossing 3 | 157
Liver Cirrhosis, Experimental 3 | 769
Mammary Neoplasms 3 | 425
Orbital separation excessive 3 | 244
Pick disease 3 | 1,894
Polycystic ovary syndrome 3 | 360
Prominent eyes 3 | 96
Prominent globes 3 | 96
Protruding eyes 3 | 96
Schizophrenia 3 | 1,160
Seizures 3 | 596
Short stature 3 | 531
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
head and neck cancer 3 | 271
posterior fossa group A ependymoma 3 | 468

Tissue

Blood and immune system 37 | 16,909
Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Female tissues 37 | 17,400
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678
Cardiovascular System 36 | 15,192
Liver and Pancreas 36 | 16,750

Target Family

Non-IDG 31 | 12,091
Kinase 3 | 634
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

UniProt Keyword

Osteogenesis 37 | 37
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Extracellular tyrosine-protein kinase PKDCC PKDCC Tbio Kinase -1.15951 16.2 51
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Bone morphogenetic protein 3 BMP3 Tbio Non-IDG -2.11354 130.5 361
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Collagen alpha-1(XIII) chain COL13A1 Tbio Non-IDG -1.17587 14.7 63
Bone morphogenetic protein 8A BMP8A Tbio Non-IDG -0.75681 5.87 138
Discoidin domain-containing receptor 2 DDR2 Tchem Kinase -2.12297 152.1 302
Chordin-like protein 2 CHRDL2 Tbio Non-IDG -1.69212 48.9 100
SUN domain-containing ossification factor SUCO Tdark Non-IDG -2.13361 126.0 4
Kazal-type serine protease inhibitor domain-containing protein 1 KAZALD1 Tdark Enzyme -0.50068 4.33 42