Development Level

Tbio 59 | 10,625
Tdark 15 | 7,003
Tchem 6 | 1,890
Tclin 3 | 602

IMPC Term

embryonic lethality prior to o... 3 | 148
preweaning lethality, complete... 3 | 633
embryonic lethality prior to t... 2 | 187
increased bone mineral content 2 | 92
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
abnormal QRS complex 1 | 25
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal embryo size 1 | 112
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal tail movements 1 | 12
decreased CD4-positive, CD25-p... 1 | 24
decreased body weight 1 | 174
decreased circulating aspartat... 1 | 27
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased total body fat amoun... 1 | 186
enlarged lymph nodes 1 | 27
enlarged urinary bladder 1 | 4
increased circulating HDL chol... 1 | 63
increased circulating aspartat... 1 | 17
increased circulating choleste... 1 | 53
increased circulating iron lev... 1 | 25
increased mean platelet volume 1 | 19
male infertility 1 | 62
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
tremors 1 | 34

Disease

osteosarcoma 46 | 7,933
ovarian cancer 37 | 8,484
glioblastoma 25 | 5,572
medulloblastoma, large-cell 25 | 6,234
psoriasis 24 | 6,685
lung cancer 19 | 4,466
malignant mesothelioma 19 | 3,162
primitive neuroectodermal tumor 19 | 3,031
group 3 medulloblastoma 18 | 2,254
atypical teratoid / rhabdoid tumor 17 | 4,369
Cancer 14 | 2,346
pediatric high grade glioma 14 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
invasive ductal carcinoma 13 | 2,950
pilocytic astrocytoma 13 | 3,086
Breast cancer 12 | 3,094
non-small cell lung cancer 12 | 2,798
Carcinoma 10 | 2,147
ependymoma 9 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
juvenile dermatomyositis 9 | 1,189
sonic hedgehog group medulloblastoma 9 | 1,482
subependymal giant cell astrocytoma 9 | 2,287
astrocytic glioma 8 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
lung carcinoma 8 | 2,844
oligodendroglioma 8 | 2,849
acute myeloid leukemia 7 | 780
adrenocortical carcinoma 7 | 1,427
hepatocellular carcinoma 7 | 532
pancreatic cancer 7 | 2,300
tuberculosis 7 | 1,557
Multiple myeloma 6 | 1,327
Pick disease 6 | 1,893
colon cancer 6 | 1,475
lung adenocarcinoma 6 | 2,713
medulloblastoma 6 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
posterior fossa group A ependymoma 6 | 1,511
primary Sjogren syndrome 6 | 789
ulcerative colitis 6 | 2,087
Waldenstrons macroglobulinemia 5 | 765
adult high grade glioma 5 | 2,148
cystic fibrosis 5 | 1,665
Influenza 4 | 142
breast carcinoma 4 | 1,614
diabetes mellitus 4 | 1,663
ductal carcinoma in situ 4 | 1,745
gastric cancer 4 | 430
group 4 medulloblastoma 4 | 1,875
interstitial cystitis 4 | 2,299
nasopharyngeal carcinoma 4 | 1,056
pituitary cancer 4 | 1,972
posterior fossa group B ependymoma 4 | 1,530
progressive supranuclear palsy 4 | 674
spina bifida 4 | 1,064
systemic lupus erythematosus 4 | 156
Acute lymphoid leukemia 3 | 25
Acute myeloid leukemia, disease 3 | 16
Acute promyelocytic leukemia, FAB M3 3 | 10
Adenocarcinoma of pancreas 3 | 12
Atopic dermatitis 3 | 944
Attention deficit hyperactivity disorder 3 | 156
Colorectal Neoplasms 3 | 217
Leukodystrophy 3 | 30
Lymphomatous meningitis 3 | 3
Malignant tumor of ovary 3 | 25
Meningeal Leukemia 3 | 7
Metastatic Breast Carcinoma 3 | 21
Multiple Sclerosis 3 | 498
Neurodegenerative disease 3 | 383
Perlman syndrome 3 | 9
Sleeping sickness 3 | 37
Treacher Collins syndrome 3 | 29
West Nile encephalitis 3 | 8
acute quadriplegic myopathy 3 | 1,157
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
cutaneous lupus erythematosus 3 | 1,056
non primary Sjogren syndrome sicca 3 | 840
pancreatic carcinoma 3 | 567
Adenoma 2 | 165
Bipolar Disorder 2 | 266
Bladder Neoplasm 2 | 109
Chronic progressive external ophthalmoplegia 2 | 18
Cockayne syndrome 2 | 54
Congenital muscular dystrophy 2 | 25
Inflammatory dermatosis 2 | 38
Kidney Diseases 2 | 86
Liver carcinoma 2 | 217
Malignant neoplasm of prostate 2 | 67
Muscular dystrophy 2 | 48
Neuropathy 2 | 210
Peripheral Neuropathy 2 | 303
dermatomyositis 2 | 933
fibroadenoma 2 | 557
gastric carcinoma 2 | 832
limb-girdle muscular dystrophy 2 | 36
substance-related disorder 2 | 105
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 72 | 17,995
Digestive Tract 72 | 18,473
Endocrine System 72 | 18,512
Female tissues 72 | 18,647
Liver and Pancreas 72 | 18,136
Male tissues 72 | 17,969
Nervous System 72 | 18,561
Respiratory system 72 | 17,484
Skin and soft tissues 72 | 18,115
Urinary Tract 72 | 18,444
Cardiovascular System 71 | 17,958

Target Family

Enzyme 78 | 4,146
Non-IDG 5 | 11,971

UniProt Keyword

Nucleotidyltransferase 83 | 83
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

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