Development Level

Tbio 41 | 11,445
Tdark 8 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
cataract 1 | 92
decreased circulating lipase l... 1 | 3
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210

Disease

Carcinoma 39 | 11,493
ovarian cancer 31 | 8,520
osteosarcoma 25 | 7,950
lung cancer 24 | 4,740
group 3 medulloblastoma 22 | 4,104
medulloblastoma, large-cell 22 | 6,241
atypical teratoid / rhabdoid tumor 17 | 5,112
glioblastoma 15 | 5,792
malignant mesothelioma 13 | 3,232
Kidney cancer 12 | 2,613
ependymoma 12 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Breast cancer 11 | 3,578
dermatomyositis 11 | 966
primitive neuroectodermal tumor 11 | 3,035
psoriasis 11 | 6,694
astrocytic glioma 10 | 2,597
oligodendroglioma 10 | 2,850
adult high grade glioma 9 | 3,801
non-small cell lung cancer 9 | 2,890
Cancer 7 | 2,499
Pick disease 7 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
Astrocytoma, Pilocytic 6 | 3,081
acute quadriplegic myopathy 6 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Multiple myeloma 5 | 1,332
Waldenstrons macroglobulinemia 5 | 765
colon cancer 5 | 1,478
invasive ductal carcinoma 5 | 2,951
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Autosomal recessive predisposition 4 | 1,442
breast carcinoma 4 | 1,638
lung carcinoma 4 | 2,843
pediatric high grade glioma 4 | 1,064
Amyotrophic lateral sclerosis 3 | 451
Atopic dermatitis 3 | 952
Gaucher disease type 1 3 | 180
Liver Cirrhosis, Experimental 3 | 769
Rheumatoid arthritis 3 | 1,191
astrocytoma 3 | 1,146
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
interstitial lung disease 3 | 298
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Dull intelligence 2 | 645
Galloway-Mowat syndrome 2 | 15
HIV Infections 2 | 102
Influenza 2 | 142
Intellectual disability 2 | 1,016
Leukemia 2 | 104
Leukemia, Myelocytic, Acute 2 | 120
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple Sclerosis 2 | 540
NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE 2 | 4
Nephrotic syndrome, idiopathic, steroid-resistant 2 | 4
Optic Atrophy 2 | 242
Poor school performance 2 | 645
Short stature 2 | 531
acute lymphocytic leukemia 2 | 33
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
interstitial cystitis 2 | 2,312
lung adenocarcinoma 2 | 2,716
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
sonic hedgehog group medulloblastoma 2 | 467
triple-A syndrome 2 | 17
46 XX gonadal dysgenesis 1 | 5
Abnormal cortical bone morphology 1 | 22
Amebiasis 1 | 21
Congenital dyserythropoietic anemia 1 | 18
Edema 1 | 81
Gonadal Dysgenesis, 46,XX 1 | 5
Inflammatory myofibroblastic tumor 1 | 8
Keloid 1 | 37
Lymphangioleiomyomatosis 1 | 16
Nail disease 1 | 9
Nystagmus, continuous pendular 1 | 14
Osteitis Deformans 1 | 11
Paget's disease of bone 1 | 36
Papillary thyroid carcinoma 1 | 43
Pendular Nystagmus 1 | 14
Pure Gonadal Dysgenesis, 46, XX 1 | 5
Spinocerebellar ataxia type 7 1 | 13
Stomatitis 1 | 21
Striatonigral Degeneration, Infantile 1 | 4
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34

Tissue

Blood and immune system 48 | 16,909
Cardiovascular System 48 | 15,192
Digestive Tract 48 | 17,369
Endocrine System 48 | 18,159
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Nervous System 48 | 16,725
Respiratory system 48 | 16,393
Skin and soft tissues 48 | 17,230
Urinary Tract 48 | 16,678

Target Family

Non-IDG 43 | 12,091
Enzyme 7 | 4,145

UniProt Keyword

Nuclear pore complex 50 | 50
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
Exportin-7 XPO7 Tbio Non-IDG -1.01893 10.2 101
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161
Nucleoporin GLE1 GLE1 Tbio Non-IDG -2.24700 173.6 150
Nuclear pore complex protein Nup160 NUP160 Tbio Non-IDG -1.13177 13.6 169
Eukaryotic translation initiation factor 5A-1 EIF5A Tbio Non-IDG -2.10288 142.0 231
Protein ELYS AHCTF1 Tbio Non-IDG -1.39546 23.9 74
Nuclear pore complex protein Nup85 NUP85 Tbio Non-IDG -1.23703 17.9 139
Nuclear pore complex-interacting protein family member A1 NPIPA1 Tdark Non-IDG -1.99373 94.6 22
Putative nuclear envelope pore membrane protein POM 121B POM121B Tdark Non-IDG 0.27 0.57 0