Development Level

Tbio 30 | 11,445
Tchem 18 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 3 | 278
abnormal sensory capabilities-... 1 | 8
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased eosinophil cell numb... 1 | 24
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased granulocyte number 1 | 1
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 40 | 11,493
osteosarcoma 28 | 7,950
ovarian cancer 28 | 8,520
glioblastoma 23 | 5,792
medulloblastoma, large-cell 20 | 6,241
psoriasis 19 | 6,694
adult high grade glioma 18 | 3,801
ependymoma 18 | 4,679
atypical teratoid / rhabdoid tumor 17 | 5,112
lung cancer 16 | 4,740
astrocytic glioma 14 | 2,597
group 3 medulloblastoma 14 | 4,104
lung carcinoma 13 | 2,843
pancreatic cancer 13 | 2,398
primitive neuroectodermal tumor 13 | 3,035
tuberculosis 13 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
malignant mesothelioma 12 | 3,232
Astrocytoma, Pilocytic 11 | 3,081
colon cancer 11 | 1,478
diabetes mellitus 11 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
oligodendroglioma 11 | 2,850
Breast cancer 10 | 3,578
Pick disease 10 | 1,894
Schizophrenia 10 | 1,160
acute quadriplegic myopathy 9 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
non-small cell lung cancer 9 | 2,890
subependymal giant cell astrocytoma 9 | 2,287
Atopic dermatitis 8 | 952
Cancer 8 | 2,499
Obesity 8 | 678
Kidney cancer 7 | 2,613
Multiple myeloma 7 | 1,332
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
group 4 medulloblastoma 7 | 1,855
juvenile dermatomyositis 7 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primary pancreatic ductal adenocarcinoma 7 | 1,109
Amyotrophic lateral sclerosis 6 | 451
Condyloma acuminatum 6 | 7
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
dermatomyositis 6 | 966
ductal carcinoma in situ 6 | 1,745
pituitary cancer 6 | 1,972
ulcerative colitis 6 | 1,819
Alzheimer's disease 5 | 658
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
Breast Neoplasms 5 | 445
Diabetes Mellitus, Experimental 5 | 108
Down syndrome 5 | 499
Epilepsy 5 | 792
Mammary Neoplasms 5 | 425
Myocardial Infarction 5 | 151
Osteoporosis 5 | 363
Rheumatoid arthritis 5 | 1,191
Seizures 5 | 596
Waldenstrons macroglobulinemia 5 | 765
active Crohn's disease 5 | 922
cutaneous lupus erythematosus 5 | 1,057
interstitial cystitis 5 | 2,312
spina bifida 5 | 1,074
Acute coronary syndrome 4 | 39
Asthma 4 | 385
Duchenne muscular dystrophy 4 | 601
Mammary Neoplasms, Experimental 4 | 154
Muscle hypotonia 4 | 571
Neurodegenerative Disorders 4 | 79
Prostatic Neoplasms 4 | 495
Stomach Neoplasms 4 | 300
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
progressive supranuclear palsy 4 | 676
Allergic hypersensitivity disease 3 | 126
Allergic rhinitis 3 | 94
Atherosclerosis 3 | 291
Depressive disorder 3 | 409
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Diarrhea 3 | 253
Hypereosinophilic syndrome 3 | 71
Lipid metabolism disorder 3 | 114
Liver Cirrhosis, Experimental 3 | 769
Myopathy 3 | 185
Neurodegenerative disease 3 | 414
Parkinson's disease 3 | 392
Vascular disease 3 | 319
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
cystic fibrosis 3 | 1,696
fibroadenoma 3 | 559
hereditary spastic paraplegia 3 | 318
medulloblastoma 3 | 720
mucosa-associated lymphoid tissue lymphoma 3 | 484

Tissue

Blood and immune system 50 | 16,909
Digestive Tract 49 | 17,369
Endocrine System 49 | 18,159
Female tissues 49 | 17,400
Skin and soft tissues 49 | 17,230
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Nervous System 48 | 16,725
Urinary Tract 47 | 16,678
Respiratory system 46 | 16,393
Cardiovascular System 43 | 15,192

Target Family

Non-IDG 28 | 12,091
Enzyme 18 | 4,145
Kinase 2 | 634
Transcription Factor 2 | 1,400
Transporter 2 | 473

UniProt Keyword

Nitration 52 | 52
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Pantothenate kinase 4 PANK4 Tdark Kinase -0.46453 3.01 101
Dynein light chain Tctex-type 3 DYNLT3 Tbio Non-IDG -0.83800 6.25 70
Zinc finger protein 432 ZNF432 Tdark Transcription Factor -0.08814 1.23 61
Aspartate aminotransferase, mitochondrial GOT2 Tbio Enzyme -3.23630 1435.0 450
Eosinophil peroxidase EPX Tbio Enzyme -2.73913 553.5 186
Dihydropyrimidinase-related protein 1 CRMP1 Tbio Enzyme -1.60377 40.8 318
Microsomal glutathione S-transferase 1 MGST1 Tbio Enzyme -2.30082 197.5 146