Development Level

Tbio 10 | 11,651
Tchem 5 | 1,388
Tdark 1 | 6,593

IMPC Phenotype

abnormal behavior 1 | 298
abnormal coat- hair morphology 1 | 19
abnormal vitreous body morphol... 1 | 10
absent vibrissae 1 | 12
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased heart left ventricle... 1 | 28
decreased total retina thickne... 1 | 17
hypoactivity 1 | 132
increased circulating glucose ... 1 | 24
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
short tibia 1 | 97

Disease

Carcinoma 11 | 11,493
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
ovarian cancer 7 | 8,520
Cancer 6 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung cancer 6 | 4,740
ulcerative colitis 6 | 1,819
glioblastoma 5 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Autoimmune lymphoproliferative syndrome type 2B 4 | 9
Vascular disease 4 | 319
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
lung adenocarcinoma 4 | 2,716
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Rheumatoid arthritis 3 | 1,191
breast carcinoma 3 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
Adenoma 2 | 167
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Arthritis, Rheumatoid 2 | 174
Asthma 2 | 385
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Colorectal Neoplasms 2 | 243
Kidney cancer 2 | 2,613
Lung Neoplasms 2 | 232
Neurodegenerative disease 2 | 414
Parkinson's disease 2 | 392
Retinitis pigmentosa 23 2 | 27
Schizophrenia 2 | 1,160
Systemic lupus erythematosus 2 | 194
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
diabetes mellitus 2 | 1,728
group 3 medulloblastoma 2 | 4,104
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung carcinoma 2 | 317
oligodendroglioma 2 | 2,850
subependymal giant cell astrocytoma 2 | 2,287
Actinic keratosis 1 | 21
Adenocarcinoma of lung (disorder) 1 | 60
Adrenal Gland Neoplasms 1 | 11
Ameloblastoma 1 | 24
Balkan Nephropathy 1 | 6
Biliary tract cancer 1 | 19
Bone cancer 1 | 16
Carotid Artery Diseases 1 | 11
Central Nervous System Neoplasms 1 | 2
Cervix carcinoma 1 | 10
Choroid Plexus Papilloma 1 | 10
Chronic Obstructive Airway Disease 1 | 37
DOID:3858 1 | 6
DOID:7919 1 | 1
DOID:8600 1 | 4
Demyelinating Diseases 1 | 7
Gastrointestinal stromal tumor 1 | 62
Genitourinary Neoplasms 1 | 3
Hemangiosarcoma 1 | 18
In situ carcinoma 1 | 3
Intestinal benign neoplasm 1 | 12
Ischemia 1 | 28
Liver Diseases, Parasitic 1 | 9
Malignant neoplasm of skin 1 | 15
Malignant peripheral nerve sheath tumor 1 | 12
Malignant tumor of colon 1 | 19
Nausea 1 | 20
Nervous System Neoplasms 1 | 8
Neurilemmoma 1 | 23
Papilledema 1 | 11
Pathological accumulation of air in tissues 1 | 10
Penile Neoplasms 1 | 4
Peritoneum cancer 1 | 3
Peutz-Jeghers syndrome 1 | 21
Polyploidy 1 | 4
Retroperitoneal cancer 1 | 4
Skin Neoplasms 1 | 69
Skin benign neoplasm 1 | 6
Small cell carcinoma of lung 1 | 45
T-Cell Lymphoma 1 | 13
Thymoma 1 | 16
Thymus cancer 1 | 1
Tumors of Adrenal Cortex 1 | 3
Upper respiratory tract disease 1 | 15
Urologic Neoplasms 1 | 8
Vulva cancer 1 | 1
Vulvar Lichen Sclerosus 1 | 2
gallbladder neoplasm 1 | 10

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192

Target Family

Non-IDG 6 | 12,091
Enzyme 5 | 4,145
Kinase 3 | 634
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

UniProt Keyword

Necrosis 16 | 16
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Receptor-interacting serine/threonine-protein kinase 3 RIPK3 Tchem Kinase -2.22748 161.7 603
Receptor-interacting serine/threonine-protein kinase 1 RIPK1 Tchem Kinase -2.33991 211.8 375
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
Gasdermin-E GSDME Tbio Non-IDG -1.63554 43.5 137
Caspase-4 CASP4 Tchem Enzyme -2.19377 147.3 520
Dynamin-1-like protein DNM1L Tbio Non-IDG -2.65717 476.9 426
Gasdermin-B GSDMB Tbio Non-IDG -1.51736 35.0 133
Transient receptor potential cation channel subfamily M member 7 TRPM7 Tbio Ion Channel -2.53154 365.5 317
Mixed lineage kinase domain-like protein MLKL Tbio Kinase -2.75630 549.8 171
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial ALKBH7 Tbio Enzyme -0.53812 4.36 42