Development Level

Tbio 116 | 10,625
Tdark 41 | 7,003
Tchem 24 | 1,890
Tclin 12 | 602

Collection

Eligible Kinase Proteins 6 | 134

IMPC Term

preweaning lethality, complete... 8 | 633
decreased total body fat amoun... 6 | 186
preweaning lethality, incomple... 5 | 260
abnormal behavior 4 | 226
decreased body length 4 | 108
decreased bone mineral content 4 | 157
decreased lean body mass 4 | 195
hyperactivity 4 | 108
abnormal bone structure 3 | 131
abnormal sleep behavior 3 | 63
decreased body weight 3 | 174
decreased circulating HDL chol... 3 | 77
decreased fasted circulating g... 3 | 49
enlarged heart 3 | 111
increased mean corpuscular hem... 3 | 93
increased or absent threshold ... 3 | 128
short tibia 3 | 82
abnormal coat appearance 2 | 25
abnormal epididymis morphology 2 | 31
abnormal heart morphology 2 | 51
abnormal retina morphology 2 | 100
abnormal retinal blood vessel ... 2 | 18
abnormal spleen morphology 2 | 36
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 85
decreased circulating free fat... 2 | 39
decreased circulating insulin ... 2 | 75
decreased mean corpuscular hem... 2 | 19
decreased startle reflex 2 | 48
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
immune system phenotype 2 | 17
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased bone mineral content 2 | 92
increased circulating alkaline... 2 | 119
increased circulating chloride... 2 | 43
increased circulating sodium l... 2 | 71
increased total body fat amoun... 2 | 57
limb grasping 2 | 35
male infertility 2 | 62
abnormal brain morphology 1 | 6
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal testis morphology 1 | 30
absent teeth 1 | 4
anophthalmia 1 | 20
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
decreased threshold for audito... 1 | 32
enlarged spleen 1 | 26
hydrops fetalis 1 | 22
hypoactivity 1 | 89
impaired righting response 1 | 19
increased KLRG1+ CD4 alpha bet... 1 | 5
increased bone mineral density 1 | 52
increased circulating amylase ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased coping response 1 | 3
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased sacral vertebrae num... 1 | 62
mydriasis 1 | 9
prenatal lethality prior to he... 1 | 64
small testis 1 | 37

Disease

ovarian cancer 94 | 8,484
osteosarcoma 92 | 7,933
medulloblastoma, large-cell 86 | 6,234
glioblastoma 82 | 5,572
atypical teratoid / rhabdoid tumor 62 | 4,369
psoriasis 60 | 6,685
pilocytic astrocytoma 52 | 3,086
primitive neuroectodermal tumor 47 | 3,031
oligodendroglioma 46 | 2,849
lung cancer 44 | 4,466
invasive ductal carcinoma 41 | 2,950
ependymoma 38 | 2,514
adult high grade glioma 36 | 2,148
lung adenocarcinoma 35 | 2,713
subependymal giant cell astrocytoma 35 | 2,287
interstitial cystitis 34 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,289
lung carcinoma 34 | 2,844
astrocytic glioma 33 | 2,241
Breast cancer 32 | 3,094
ulcerative colitis 32 | 2,087
astrocytoma 31 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,956
ductal carcinoma in situ 30 | 1,745
malignant mesothelioma 30 | 3,162
medulloblastoma 29 | 1,524
pediatric high grade glioma 29 | 2,712
Pick disease 28 | 1,893
group 4 medulloblastoma 28 | 1,875
non-small cell lung cancer 28 | 2,798
Cancer 27 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,988
tuberculosis 27 | 1,557
breast carcinoma 25 | 1,614
cystic fibrosis 25 | 1,665
pancreatic cancer 24 | 2,300
group 3 medulloblastoma 23 | 2,254
pituitary cancer 22 | 1,972
cutaneous lupus erythematosus 21 | 1,056
Multiple myeloma 20 | 1,327
colon cancer 20 | 1,475
posterior fossa group A ependymoma 18 | 1,511
Rheumatoid Arthritis 17 | 1,160
atypical teratoid/rhabdoid tumor 17 | 1,095
posterior fossa group B ependymoma 17 | 1,530
primary pancreatic ductal adenocarcinoma 17 | 1,271
juvenile dermatomyositis 16 | 1,189
sonic hedgehog group medulloblastoma 15 | 1,482
Carcinoma 14 | 2,147
Waldenstrons macroglobulinemia 14 | 765
spina bifida 14 | 1,064
dermatomyositis 13 | 933
esophageal adenocarcinoma 13 | 737
diabetes mellitus 12 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
primary Sjogren syndrome 12 | 789
active Crohn's disease 11 | 918
acute myeloid leukemia 11 | 780
adrenocortical carcinoma 11 | 1,427
fibroadenoma 11 | 557
non primary Sjogren syndrome sicca 11 | 840
tuberculosis and treatment for 6 months 11 | 686
Blastic phase chronic myeloid leukemia 10 | 58
Chronic Myelocytic Leukemia Accelerated Phase 10 | 59
Duchenne muscular dystrophy 10 | 602
acute quadriplegic myopathy 10 | 1,157
gastric carcinoma 10 | 832
Alzheimer's disease 9 | 644
Down syndrome 9 | 548
Mammary Neoplasms 9 | 410
progressive supranuclear palsy 9 | 674
Atopic dermatitis 8 | 944
Chronic Lymphocytic Leukemia 8 | 242
Chronic phase chronic myeloid leukemia 8 | 45
Crohn's disease 8 | 304
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 8 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 8 | 47
chronic lymphosyte leukemia 8 | 232
sarcoidosis 8 | 358
Kidney disease 7 | 396
Obesity 7 | 616
active ulcerative colitis 7 | 477
aldosterone-producing adenoma 7 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
mucosa-associated lymphoid tissue lymphoma 7 | 480
Acquired metabolic disease 6 | 267
Endometriosis 6 | 535
Heart disease 6 | 279
Retinitis pigmentosa 6 | 153
Schizophrenia 6 | 501
facioscapulohumeral dystrophy 6 | 286
Bipolar Disorder 5 | 266
Diarrhea 5 | 155
Myocardial Ischemia 5 | 169
Prostatic Neoplasms 5 | 471
Stomach Neoplasms 5 | 282
hereditary spastic paraplegia 5 | 313
periodontitis 5 | 269
nephrosclerosis 4 | 329
urothelial carcinoma 4 | 318

Tissue

Digestive Tract 182 | 18,473
Endocrine System 182 | 18,512
Female tissues 182 | 18,647
Liver and Pancreas 182 | 18,136
Urinary Tract 182 | 18,444
Cardiovascular System 181 | 17,958
Nervous System 181 | 18,561
Male tissues 180 | 17,969
Respiratory system 180 | 17,484
Blood and immune system 179 | 17,995
Skin and soft tissues 179 | 18,115

Target Family

Non-IDG 111 | 11,971
Enzyme 58 | 4,146
Kinase 21 | 634
Epigenetic 1 | 242
Ion Channel 1 | 341
Transporter 1 | 473

UniProt Keyword

Myristate 193 | 193
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dymeclin DYM Tbio Non-IDG -1.45800 31.6 59
Protein Niban FAM129A Tbio Non-IDG -1.03213 12.4 149
DCN1-like protein 3 DCUN1D3 Tdark Non-IDG -0.34242 2.58 44
Endogenous retrovirus group K member 9 Gag polyprotein ERVK-9 Tdark Non-IDG 0.00000 0
Endogenous retrovirus group K member 7 Gag polyprotein ERVK-7 Tdark Non-IDG 0.00000 0
Endogenous retrovirus group K member 24 Gag polyprotein ERVK-24 Tdark Non-IDG 0.00000 0
Endogenous retrovirus group K member 9 Pol protein ERVK-9 Tdark Non-IDG 0.00000 0
Phosphatase and actin regulator 2 PHACTR2 Tbio Enzyme -0.48667 0.00000 71
Recoverin RCVRN Tbio Non-IDG -2.41555 275.7 360
TLD domain-containing protein 1 TLDC1 Tdark Non-IDG 0.00000 110