Development Level

Tbio 8 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
tremors 2 | 39
abnormal embryo size 1 | 220
abnormal stomach morphology 1 | 10
decreased blood urea nitrogen ... 1 | 51
decreased lean body mass 1 | 135
embryonic lethality prior to o... 1 | 239
hemorrhage 1 | 23
increased body weight 1 | 25
vertebral fusion 1 | 23

Disease

Myopathy 9 | 185
Carcinoma 7 | 11,493
Myofibrillar Myopathy 7 | 9
Cardiomyopathy 6 | 116
psoriasis 6 | 6,694
Creatine phosphokinase serum increased 5 | 110
EMG: myopathic abnormalities 5 | 22
Elevated creatine kinase 5 | 110
Muscular dystrophy 5 | 75
ovarian cancer 5 | 8,520
Cardiomyopathy, Dilated 4 | 83
Dilated cardiomyopathy 4 | 56
Familial isolated dilated cardiomyopathy 4 | 41
LEFT VENTRICULAR NONCOMPACTION 10 4 | 40
LEFT VENTRICULAR NONCOMPACTION 8 4 | 40
Muscle biopsy shows dystrophic changes 4 | 39
Muscle fiber splitting 4 | 7
colon cancer 4 | 1,478
Adult onset 3 | 82
Cardiomyopathies 3 | 110
Decreased tendon reflex 3 | 122
Distal limb muscle weakness due to peripheral neuropathy 3 | 62
Distal muscle weakness 3 | 62
Hypertrophic Cardiomyopathy 3 | 117
Hyporeflexia of lower limbs 3 | 10
Peripheral Neuropathy 3 | 134
Slow progression 3 | 89
astrocytoma 3 | 1,146
lung cancer 3 | 4,740
Astrocytoma, Pilocytic 2 | 3,081
Autophagic vaculoes (finding) 2 | 3
Autosomal recessive predisposition 2 | 1,442
Bell Palsy 2 | 58
Facial Paresis 2 | 59
Facial muscle weakness of muscles innervated by CN VII 2 | 58
Foot dorsiflexor weakness 2 | 27
Foot-drop 2 | 27
Hypernasal voice 2 | 39
Late-onset proximal muscle weakness 2 | 2
Muscle Weakness 2 | 170
Muscle fiber cytoplasmatic inclusion bodies 2 | 2
Muscle weakness, distal, progressive 2 | 2
Nasal voice 2 | 39
Neck muscle weakness 2 | 17
Pick disease 2 | 1,894
Polyneuropathy 2 | 64
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Rapidly progressive 2 | 27
Rapidly progressive disorder 2 | 27
Respiratory Failure 2 | 104
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Respiratory insufficiency due to muscle weakness 2 | 37
Waddling gait 2 | 34
atypical teratoid / rhabdoid tumor 2 | 5,112
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
esophageal adenocarcinoma 2 | 737
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
limb-girdle muscular dystrophy 2 | 37
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
non diabetic and post-ischemic heart failure 2 | 200
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
Alexander disease 1 | 11
Aspergillosis 1 | 26
Avian influenza 1 | 7
Bronchiectasis 1 | 64
CARDIOMYOPATHY, DILATED, 1I 1 | 1
Congenital Fiber Type Disproportion 1 | 7
Congenital myopathy with fiber type disproportion 1 | 9
Flexion contracture - elbow 1 | 32
Glomerulonephritis 1 | 46
Hernias, Diaphragmatic, Congenital 1 | 17
MYOPATHY, MYOFIBRILLAR, DESMIN-RELATED 1 | 1
Muscular stiffness 1 | 12
Myofibrillar myopathy 4 1 | 4
Neurodegenerative Diseases 1 | 38
Peroneal muscle atrophy 1 | 2
Pneumocystosis 1 | 17
Restrictive heart failure 1 | 1
Rigid spine muscular dystrophy 1 1 | 14
Rimmed vacuoles on biopsy 1 | 15
Scapular weakness 1 | 23
Scapuloperoneal Syndrome, Neurogenic, Kaeser Type 1 | 1
Scapuloperoneal weakness 1 | 3
Shoulder girdle muscle atrophy 1 | 6
Sinusitis 1 | 65
Weak cry 1 | 17
Winged scapula 1 | 23
alcohol use disorder 1 | 12

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 2 | 4,145

UniProt Keyword

Myofibrillar myopathy 9 | 9
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmin DES Tbio Non-IDG -1.56068 36.6 991
BAG family molecular chaperone regulator 3 BAG3 Tbio Non-IDG -2.26339 208.9 289
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 PYROXD1 Tdark Enzyme 0.36 0.20 47
Selenoprotein N SELENON Tbio Non-IDG -1.95384 87.6 96
Kyphoscoliosis peptidase KY Tbio Enzyme -0.33579 2.14 68
Myotilin MYOT Tbio Non-IDG -1.90038 80.3 177
Alpha-crystallin B chain CRYAB Tbio Non-IDG -2.29243 192.0 1100
LIM domain-binding protein 3 LDB3 Tbio Non-IDG -2.87973 736.4 182
Filamin-C FLNC Tbio Non-IDG -2.91122 814.9 94